The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
Effect of a chlorhexidine mouthrinse on plaque, gingival inflammation and staining in gingivitis patients: a systematic review
Abstract
Aim: To systematically evaluate the efficacy of chlorhexidine (CHX) mouthrinses on plaque, gingival inflammation and staining in gingivitis patients. Material & Methods: Medline, EMBASE and Cochrane Central Register of Controlled Trials were searched through April 2011. Randomized controlled clinical trials comparing CHX to placebo/control mouthrinses or oral hygiene (OH) ≥4 weeks were included. Results: Among 1355 titles, 30 publications fulfilled the selection criteria. Meta‐analysis (MA) showed significant weighted mean differences (WMD) favouring CHX. This was −0.39 [95% CI: −0.70; −0.08] for the Plaque Index Silness & Löe, −0.67 [95% CI: −0.82; −0.52] for the Plaque‐Index Quigley & Hein (PIQH), −0.32 [95% CI: −0.42; −0.23] for the Gingival Index (GI), −0.08 [95% CI: −0.10; −0.05] for the bleeding aspect of the GI, −0.21 [95% CI: −0.37; −0.04] for the Papillary BI eeding Index, −0.16 [95% CI: −0.26; −0.07] for Bleeding on Marginal Probing and 0.91 [95% CI: 0.12;1.70] for the L obene Stain Index. MA of studies with a low risk of author‐estimated bias showed a WMD of −0.68 [95% CI: −0.85; −0.51] for the PIQH and −0.24 [95% CI: −0.29; −0.20] for the GI in favour of CHX. Relative to control, the reduction with CHX for plaque was 33% and for gingivitis 26%. CHX rinsing groups demonstrated significantly more staining. Conclusions: In gingivitis patients, CHX mouthrinses together with OH versus placebo‐ or control mouthrinse provide significant reductions in plaque and gingivitis scores, but a significant increase in staining score.
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Cites
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Baijens, L. W., Clavé, P., Cras, P., Ekberg, O., Forster, A., Kolb, G., Leners, J. C., Masiero, S., Mateos del Nozal, J., Ortega, O., et al. (2016) · Clinical Interventions in Aging · doi:10.2147/cia.s107750 · Cited by 773
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Self-citation
Metadata
- Authors
- Van Strydonck, D. A. C., Slot, D. E., Van der Velden, U., & Van der Weijden, F.
- Venue
- Journal of Clinical Periodontology
- Publisher
- Wiley
- Published
- 2012-09-07
- Volume
- 39
- Issue
- 11
- Pages
- 1042-1055
- ISSN
- 0303-6979 (ISSN-L)
- 1600-051X
- OpenAlex
- W2095793607
- Cited by
- 353
- References
- 84
- FWCI
- 6.90
- Type
- journal article
- Language
- en
- Open access
- closed
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