Cited by 49Oral microbiology and periodontitis researchDental Health and Care UtilizationDental Erosion and Treatment

Plaque control and reduction of gingivitis: The evidence for dentifrices

Open access
Valkenburg, Cees, Van der Weijden, Fridus A., Slot, Dagmar E.·2019·Periodontology 2000

Abstract

This paper focuses on plaque control and the management of gingivitis in adults and summarizes the evidence of commercially available dentifrices as gathered from existing systematic reviews. Three internet sources were used to search for appropriate papers (up to and including February 2017). The search strategy was designed to include any systematic review published on dentifrices that also included an evaluation of plaque and gingivitis scores. Characteristics of the individual reviews, such as methodological aspects, quantitative data and conclusions, were extracted. The potential risk of bias was estimated and the acquired evidence was graded. Independent screening of 205 unique reviews resulted in 10 published and eligible systematic reviews. One publication evaluated the mechanical contribution of dentifrice to plaque removal. Eight papers were identified that evaluated the efficacy of a proposed single active ingredients, of which two reviewed more than one potentially active ingredient. One study compared two active ingredients. This meta‐review appraised the current state of evidence and found that toothbrushing with a standard fluoride dentifrice does not provide an added effect for the mechanical removal of dental plaque. Evidence suggests that compared with a standard dentifrice, those containing triclosan or stannous fluoride have benefits with respect to gingival health and control of dental plaque.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1111/prd.12257

Cites

79 of 79 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Chemical adjuncts in dentifrices and mouthrinses provide additional benefits in prevention of gingivitis.

    “However, chemical adjuncts in dentifrices and mouthrinses have been demonstrated to provide additional benefits in the prevention of gingivitis.11,12”
  • Only dentifrices containing additional anti-inflammatory agents such as triclosan or stannous fluoride have been found to provide additional effects on plaque removal and gingival health, but not a standard fluoride dentifrice.

    “Only dentifrices containing additional anti-inflammatory agents such as triclosan or stannous fluoride have been found to provide additional effects on plaque removal and gingival health, but not a standard fluoride dentifrice.4,11,12,57”

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 3

  1. [34]Higgins JP, Green S. Cochrane Handbook for Systematic Reviews of Interventions. Chichester: Wiley‐Blackwell; 2008.
  2. [48]Food Drug Administration (FDA). Oral health care drug products for over‐the‐counter human use; tentative final monograph for oral antiseptic drug products. Fed Regist. 1994; 59: 6084– 6124.
  3. [78]Goodchild van Hilten L. Why it's time to publish research “failures”. https://www.elsevier.com/connect/scientists-we-want-your-negative-results-too. Accessed March 27, 2017.

Cited by

Sorted by citations

Authors
Valkenburg, C., Van der Weijden, F. A., & Slot, D. E.
Affiliations
  • Academic Center for Dentistry Amsterdam (NL)
  • Department of Periodontology Academic Centre for Dentistry Amsterdam (ACTA) University of Amsterdam and Vrije Universiteit Amsterdam Amsterdam The Netherlands
Corresponding author
Slot, Dagmar E.
Venue
Periodontology 2000
Publisher
Wiley
Published
2019-02
Volume
79
Issue
1
Pages
221-232
ISSN
  • 0906-6713 (ISSN-L)
  • 1600-0757
OpenAlex
W2924360996
Cited by
49
References
79
Citations by year
2026: 6 · 2025: 5 · 2024: 9 · 2023: 8 · 2022: 9 · 2021: 2 · 2020: 7 · 2019: 3
FWCI
0.74
Type
journal article
Language
en
Open access
Locations
  • Periodontology 2000 (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • VU Research Portal (publishedVersion, cc-by)
  • UvA-DARE (University of Amsterdam) (submittedVersion, cc-by)
  • Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
  • Data Archiving and Networked Services (DANS) (submittedVersion, cc-by)
Topics
  • Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
  • Health Sciences › Dentistry › Periodontics › Dental Health and Care Utilization
  • Health Sciences › Dentistry › Orthodontics › Dental Erosion and Treatment
Keywords
toothpaste, plaque control, gingivitis, toothbrushing, fluoride toothpaste, triclosan, stannous fluoride, gingival health, active ingredients
MeSH terms
Adult, Analysis of Variance, Dental Plaque, Dentifrices, Double-Blind Method, Gingivitis, Humans, Periodontal Index

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review