CoChat
Sign Up
Cited by 71melanin and skin pigmentationMelanoma and MAPK PathwaysHair Growth and Disorders

Comparative analysis of melanins and melanosomes produced by various coat color mutants

PROTA, GIUSEPPE, LAMOREUX, M. LYNN, MULLER, JACQUELINE, KOBAYASHI, TAKESHI, NAPOLITANO, ALESSANDRA, VINCENSI, M. ROSARIA, SAKAI, CHIE, HEARING, VINCENT J.·1995·Pigment Cell Research
DOI 10.1111/j.1600-0749.1995.tb00657.x
Open this paper in CoChat — free account

Abstract

Pigmentation in the skin, hair, and eyes of animals is influenced by a number of genes that modulate the activity of melanocytes, the intervention of enzymatic controls at different stages of the melanogenic process, and the physico-chemical properties of the final pigment. The results of combined phenotypic, ultrastructural, biochemical, and chemical analyses of hairs of a variety of defined genotypes on a common genetic background performed in this study are consistent with the view that pigmentation of dark to black hairs results from the incorporation of eumelanin pigments whereas that of yellow hairs results from the incorporation of eu- and pheomelanins. It is also clear that relatively minor differences in melanin content can have dramatic effects on visible hair color. A good correlation was found for expression of (and enzyme activities associated with) TRP1 and TRP2 with eumelanin synthesis and eumelanosome production.

Integrity signals

Registry

Crossref · 10.1111/j.1600-0749.1995.tb00657.x

Cites

52 of 52 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Combinatorial effects are observed in mouse models when double-mutant homozygous mice are compared to mice harboring homozygous mutations in either gene alone.

    “Combinatorial effects are also observed in mouse models, when mutant melanogenic gene alleles being considered in double-mutant homozygous mice are compared to mice harboring homozygous mutations in either gene alone (Prota et al., 1995;Lehman et al., 2000).”

    From Analysis of Cultured Human Melanocytes Based on Polymorphisms within the SLC45A2/MATP, SLC24A5/NCKX5, and OCA2/P Loci (2009) · cites this paper as Prota et al., 1995

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
PROTA, G., LAMOREUX, M. L., MULLER, J., KOBAYASHI, T., NAPOLITANO, A., VINCENSI, M. R., SAKAI, C., & HEARING, V. J.
Affiliations
  • University of Naples Federico II (IT)
  • Texas A&M University (US)
  • National Institutes of Health (US)
Corresponding author
HEARING, VINCENT J.
ORCID
Venue
Pigment Cell Research
Publisher
Wiley
Published
1995-06
Volume
8
Issue
3
Pages
153-163
ISSN
  • 0893-5785 (ISSN-L)
  • 1600-0749
DOI
10.1111/j.1600-0749.1995.tb00657.x
OpenAlex
W2074515433
Cited by
71
References
52
Citations by year
2024: 3 · 2018: 1 · 2017: 3 · 2015: 2 · 2013: 1
FWCI
2.30
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 4075 d)
Locations
  • Pigment Cell Research (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Melanoma and MAPK Pathways
  • Health Sciences › Medicine › Urology › Hair Growth and Disorders
Keywords
melanin, melanosomes, eumelanin, pheomelanin, hair pigmentation, melanocyte differentiation, TRP-1, TRP-2, melanogenesis, black hair
MeSH terms
Animals, Chemistry, Physical, Genotype, Hair, Hair Color, Melanins, Melanocytes, Mice, Inbred C57BL, Mice, Inbred DBA, Microscopy, Electron, Mutation, Phenotype, Pigments, Biological, Mice, Chemical Phenomena

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review