The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Hypothermic Machine Preservation in Human Liver Transplantation: The First Clinical Series
Open accessAbstract
Hypothermic machine perfusion (HMP) is widely used to preserve kidneys for transplantation with improved results over cold storage (CS). To date, successful transplantation of livers preserved with HMP has been reported only in animal models. In this, the first prospective liver HMP study, 20 adults received HMP-preserved livers and were compared to a matched group transplanted with CS livers. HMP was performed for 3-7 h using centrifugal perfusion with Vasosol solution at 4-6 degrees C. There were no cases of primary nonfunction in either group. Early allograft dysfunction rates were 5% in the HMP group versus 25% in controls (p = 0.08). At 12 months, there were two deaths in each group, all unrelated to preservation or graft function. There were no vascular complications in HMP livers. Two biliary complications were observed in HMP livers compared with four in the CS group. Serum injury markers were significantly lower in the HMP group. Mean hospital stay was shorter in the HMP group (10.9 +/- 4.7 days vs. 15.3 +/- 4.9 days in the CS group, p = 0.006). HMP of donor livers provided safe and reliable preservation in this pilot case-controlled series. Further multicenter HMP trials are now warranted.
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Cites
RISK FACTORS FOR PRIMARY DYSFUNCTION AFTER LIVER TRANSPLANTATION—A MULTIVARIATE ANALYSIS
PLOEG, R. J., DʼALESSANDRO, A. M., KNECHTLE, S. J., STEGALL, M. D., PIRSCH, J. D., HOFFMANN, R. M., SASAKI, T., SOLLINGER, H. W., BELZER, F. O., & KALAYOGLU, M. (1993) · Transplantation · doi:10.1097/00007890-199304000-00024 · Cited by 1,026
Machine Perfusion or Cold Storage in Deceased-Donor Kidney Transplantation
Moers, C., Smits, J. M., Maathuis, M.-H. J., Treckmann, J., van Gelder, F., Napieralski, B. P., van Kasterop-Kutz, M., van der Heide, J. J. H., Squifflet, J.-P., van Heurn, E., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0802289 · Cited by 1,020
EARLY ALLOGRAFT DYSFUNCTION AFTER LIVER TRANSPLANTATION: A Definition and Predictors of Outcome1
Desch??nes, M., Belle, S. H., Krom, R. A. F., Zetterman, R. K., & Lake, J. R. (1998) · Transplantation · doi:10.1097/00007890-199808150-00005 · Cited by 251
Liver and kidney preservation by perfusion
St Peter, S. D., Imber, C. J., & Friend, P. J. (2002) · The Lancet · doi:10.1016/s0140-6736(02)07749-8 · Cited by 199
Biliary Complications and Outcomes of Liver Transplantation from Donors after Cardiac Death
Maheshwari, A., Maley, W., Li, Z., & Thuluvath, P. J. (2007) · Liver Transplantation · doi:10.1002/lt.21212 · Cited by 171
Schold, J. D., Kaplan, B. E., Howard, R. J., Reed, A., Foley, D. P., & Meier‐Kriesche, H. (2005) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2005.00910.x · Cited by 157
THE INFLUENCE OF PULSATILE PRESERVATION ON RENAL TRANSPLANTATION IN THE 1990s 1
Polyak, M. M. R., Arrington, B. O., Stubenbord, W. T., Boykin, J., Brown, T., Jean-Jacques, M. A., Estevez, J., Kapur, S., & Kinkhabwala, M. M. (2000) · Transplantation · doi:10.1097/00007890-200001270-00010 · Cited by 134
Self-citationSEVENTY-TWO-HOUR PRESERVATION OF THE CANINE LIVER BY MACHINE PERFUSION
Pienaar, B., Lindell, S. L., van Gulik, T. M., Southard, J. H., & Belzer, F. O. (1990) · Transplantation · doi:10.1097/00007890-199002000-00005 · Cited by 122
Machine Perfusion Preservation Improves Renal Allograft Survival
Kwiatkowski, A., Wszola, M., Kosieradzki, M., Danielewicz, R., Ostrowski, K., Domagała, P., Lisik, W., Nosek, R., Fesołowicz, S., Trzebicki, J., et al. (2007) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2007.01877.x · Cited by 80
van der Plaats, A., Maathuis, M. H. J., Hart, N. A. ‘., Bellekom, A. A., Hofker, H. S., van der Houwen, E. B., Verkerke, G. J., Leuvenink, H. G. D., Verdonck, P., Ploeg, R. J., et al. (2006) · Annals of Biomedical Engineering · doi:10.1007/s10439-006-9207-4 · Cited by 72
Cited by
Hypothermic Machine Perfusion in Liver Transplantation — A Randomized Trial
van Rijn, R., Schurink, I. J., de Vries, Y., van den Berg, A. P., Cortes Cerisuelo, M., Darwish Murad, S., Erdmann, J. I., Gilbo, N., de Haas, R. J., Heaton, N., et al. (2021) · New England Journal of Medicine · doi:10.1056/nejmoa2031532 · Cited by 649
Guarrera, J. V., Henry, S. D., Samstein, B., Reznik, E., Musat, C., Lukose, T. I., Ratner, L. E., Brown, R. S., Kato, T., & Emond, J. C. (2015) · American Journal of Transplantation · doi:10.1111/ajt.12958 · Cited by 323
Self-citationProtective mechanisms of end-ischemic cold machine perfusion in DCD liver grafts
Schlegel, A., Rougemont, O. D., Graf, R., Clavien, P.-A., & Dutkowski, P. (2013) · Journal of Hepatology · doi:10.1016/j.jhep.2012.10.004 · Cited by 274
Challenges to Liver Transplantation and Strategies to Improve Outcomes
Dutkowski, P., Linecker, M., DeOliveira, M. L., Müllhaupt, B., & Clavien, P.-A. (2015) · Gastroenterology · doi:10.1053/j.gastro.2014.08.045 · Cited by 270
Bruinsma, B. G., Yeh, H., Özer, S., Martins, P. N., Farmer, A., Wu, W., Saeidi, N., Op den Dries, S., Berendsen, T. A., Smith, R. N., et al. (2014) · American Journal of Transplantation · doi:10.1111/ajt.12727 · Cited by 187
Metadata
- Authors
- Guarrera, J. V., Henry, S. D., Samstein, B., Odeh-Ramadan, R., Kinkhabwala, M., Goldstein, M. J., Ratner, L. E., Renz, J. F., Lee, H. T., Brown, R. S., & Emond, J. C.
- Venue
- American Journal of Transplantation
- Publisher
- Elsevier BV
- Published
- 2010-02
- Volume
- 10
- Issue
- 2
- Pages
- 372-381
- ISSN
- 1600-6135 (ISSN-L)
- OpenAlex
- W2050387987
- Cited by
- 555
- References
- 11
- FWCI
- 22.14
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Guarrera, J. V., Henry, S. D., Samstein, B., Odeh-Ramadan, R., Kinkhabwala, M., Goldstein, M. J., Ratner, L. E., Renz, J. F., Lee, H. T., Brown, R. S., & Emond, J. C. (2010). Hypothermic Machine Preservation in Human Liver Transplantation: The First Clinical Series. American Journal of Transplantation. https://doi.org/10.1111/j.1600-6143.2009.02932.x
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