Cited by 1,882Statistical Methods in EpidemiologyMeta-analysis and systematic reviewsClinical Laboratory Practices and Quality Control

The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.

Understanding diagnostic tests 3: receiver operating characteristic curves

Akobeng, Anthony K·2007·Acta Paediatrica

DOI 10.1111/j.1651-2227.2006.00178.x

Open this paper in CoChat — free account

Abstract

The results of many clinical tests are quantitative and are provided on a continuous scale. To help decide the presence or absence of disease, a cut‐off point for ‘normal’ or ‘abnormal’ is chosen. The sensitivity and specificity of a test vary according to the level that is chosen as the cut‐off point. The receiver operating characteristic (ROC) curve, a graphical technique for describing and comparing the accuracy of diagnostic tests, is obtained by plotting the sensitivity of a test on the y axis against 1‐specificity on the x axis. Two methods commonly used to establish the optimal cut‐off point include the point on the ROC curve closest to (0, 1) and the Youden index. The area under the ROC curve provides a measure of the overall performance of a diagnostic test. In this paper, the author explains how the ROC curve can be used to select optimal cut‐off points for a test result, to assess the diagnostic accuracy of a test, and to compare the usefulness of tests. Conclusion: The ROC curve is obtained by calculating the sensitivity and specificity of a test at every possible cut‐off point, and plotting sensitivity against 1‐specificity. The curve may be used to select optimal cut‐off values for a test result, to assess the diagnostic accuracy of a test, and to compare the usefulness of different tests.

Integrity signals

Registry

Crossref · 10.1111/j.1651-2227.2006.00178.x

Cites

17 of 17 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Estimation of the Youden Index and its Associated Cutoff Point
Fluss, R., Faraggi, D., & Reiser, B. (2005) · Biometrical Journal · doi:10.1002/bimj.200410135 · Cited by 2,656
Principles and practical application of the receiver-operating characteristic analysis for diagnostic tests
Greiner, M., Pfeiffer, D., & Smith, R. D. (2000) · Preventive Veterinary Medicine · doi:10.1016/s0167-5877(00)00115-x · Cited by 1,923
The Inconsistency of “Optimal” Cutpoints Obtained using Two Criteria based on the Receiver Operating Characteristic Curve
Perkins, N. J., & Schisterman, E. F. (2006) · American Journal of Epidemiology · doi:10.1093/aje/kwj063 · Cited by 1,794
A readers' guide to the interpretation of diagnostic test properties: clinical example of sepsis
Fischer, J. E., Bachmann, L. M., & Jaeschke, R. (2003) · Intensive Care Medicine · doi:10.1007/s00134-003-1761-8 · Cited by 890
Understanding diagnostic tests 1: sensitivity, specificity and predictive values
Akobeng, A. K. (2007) · Acta Paediatrica · doi:10.1111/j.1651-2227.2006.00180.x · Cited by 711
Self-citation
Statistics Notes: Diagnostic tests 3: receiver operating characteristic plots
Altman, D. G., & Bland, J. M. (1994) · BMJ · doi:10.1136/bmj.309.6948.188 · Cited by 599
ROC Curves in Clinical Chemistry: Uses, Misuses, and Possible Solutions
Obuchowski, N. A., Lieber, M. L., & Wians, F. H. (2004) · Clinical Chemistry · doi:10.1373/clinchem.2004.031823 · Cited by 358
How to report statistics in medicine: annotated guidelines for authors, editors, and reviewers
(1997) · Choice Reviews Online · doi:10.5860/choice.35-1556 · Cited by 309
Diagnostic markers of infection: comparison of procalcitonin with C reactive protein and leucocyte count
Hatherill, M., Tibby, S. M., Sykes, K., Turner, C., & Murdoch, I. (1999) · Archives of Disease in Childhood · doi:10.1136/adc.81.5.417 · Cited by 260
How to Report Statistics in Medicine
Lang, T. A., & Secic, M. (1997) · The Nurse Practitioner · doi:10.1097/00006205-199705000-00022 · Cited by 209

Show all 17 references

Research works printed but not linked: 1

Akobeng AK, Understanding diagnostic tests 2: using likelihood ratios to estimate probability of disease, Acta Paediatr

Sorted by citations

Items 701–800 of 1,001

Distinct acoustic features in spinal and bulbar muscular atrophy patients with laryngospasm
Tanaka, S., Banno, H., Katsuno, M., Suzuki, K., Suga, N., Hashizume, A., Mano, T., Araki, A., Watanabe, H., Adachi, H., et al. (2013) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2013.12.010 · Cited by 18
Preoperative Endoscopic and Radiologic Evaluation of Bariatric Patients: What Do They Add?
Ghaderi, I., Gondal, A. B., Samamé, J., Serrot, F. J., & Galvani, C. A. (2019) · Journal of Gastrointestinal Surgery · doi:10.1007/s11605-019-04219-8 · Cited by 18
Using relative handgrip strength to identify children at risk of sarcopenic obesity
Gontarev, S., Jakimovski, M., & Georgiev, G. (2020) · Nutrición Hospitalaria · doi:10.20960/nh.02977 · Cited by 18
Right ventriculo–pulmonary arterial uncoupling and poor outcomes in pulmonary arterial hypertension
Nakaya, T., Ohira, H., Sato, T., Watanabe, T., Nishimura, M., Oyama‐Manabe, N., Kato, M., Ito, Y. M., & Tsujino, I. (2020) · Pulmonary Circulation · doi:10.1177/2045894020957223 · Cited by 18
Effectiveness of HPV 16 viral load and the E2/E6 ratio for the prediction of cervical cancer risk among Chinese women
Chang, L., He, X., Yu, G., & Wu, Y. (2013) · Journal of Medical Virology · doi:10.1002/jmv.23490 · Cited by 18
Surgical outcomes after cardiac surgery in liver transplant recipients
Ota, T., Rocha, R. V., Wei, L. M., Toyoda, Y., Gleason, T. G., & Bermudez, C. A. (2012) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2012.09.099 · Cited by 18
A novel simplified thrombo-inflammatory prognostic score for predicting in-hospital complications and long-term mortality in patients with type A acute aortic dissection: a prospective cohort study
Li, D., Li, X. M., Sun, H., Yang, Y., Ma, Y.-T., Qu, Y.-M., Ma, X., & Liu, F. (2015) · European Heart Journal Supplements · doi:10.1093/eurheartj/suv032 · Cited by 18
Contribution of Age and Balance Confidence to Functional Mobility Test Performance
Medley, A., & Thompson, M. E. (2014) · Journal of Geriatric Physical Therapy · doi:10.1519/jpt.0000000000000015 · Cited by 18
The Multiple Hop Test
Eechaute, C., Bautmans, I., Hertogh, W. D., & Vaes, P. (2012) · Clinical Journal of Sport Medicine · doi:10.1097/jsm.0b013e31824a5761 · Cited by 18
Questionnaire-based algorithm for assessing occupational noise exposure of construction workers
Lewkowski, K., McCausland, K., Heyworth, J. S., Li, I. W., Williams, W., & Fritschi, L. (2017) · Occupational and Environmental Medicine · doi:10.1136/oemed-2017-104381 · Cited by 18
Waist-to-height ratio and body roundness index: superior predictors of insulin resistance in Chinese adults and take gender and age into consideration
Li, A., Liu, Y., Liu, Q., Peng, Y., Liang, Q., Tao, Y., Liu, Y., Cui, C., Ren, Q., Zhou, Y., et al. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1480707 · Cited by 20
Risk Factors for Falls in Patients with Alzheimer Disease: A Retrospective Study of Balance, Cognition, and Visuospatial Ability
Oki, M., Matsumoto, M., Yoshikawa, Y., Fukushima, M., Nagasawa, A., Takakura, T., & Suzuki, Y. (2021) · Dementia and Geriatric Cognitive Disorders Extra · doi:10.1159/000514285 · Cited by 17
Prediction of Reduced Gait Speed Using 5-Time Sit-to-Stand Test in Healthy Older Adults
de Abreu, D. C. C., Porto, J. M., Tofani, P. S., Braghin, R. D. M. B., & Júnior, R. C. F. (2021) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2021.11.002 · Cited by 17
Meckel’s Diverticulum in Children: A Monocentric Experience and Mini-Review of Literature
Nissen, M., Sander, V., Rogge, P., Alrefai, M., & Tröbs, R. (2022) · Children · doi:10.3390/children9010035 · Cited by 17
Value of Bile Acids in Diagnosing Hepatitis C Virus-Induced Liver Cirrhosis and Hepatocellular Carcinoma
Khalil, A. A., Elsheashaey, A., Abdelsameea, E., Obada, M., Mohamed Bayomy, F. F., & El‐Said, H. (2022) · British Journal of Biomedical Science · doi:10.3389/bjbs.2021.10191 · Cited by 17
sFlt-1 to PlGF ratio cut-offs to predict adverse pregnancy outcomes in early-onset FGR and SGA: a prospective observational study
Bonacina, E., Armengol‐Alsina, M., Hurtado, I., García‐Manau, P., Ferrer‐Oliveras, R., Monreal, S., Pancorbo, M., Mendoza, M., & Carreras, E. (2022) · Journal of Obstetrics and Gynaecology · doi:10.1080/01443615.2022.2109956 · Cited by 17
Assessment of QRISK3 as a predictor of cardiovascular disease events in type 2 diabetes mellitus
Mu, X., Wu, A., Hu, H., Zhou, H., & Yang, M. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.1077632 · Cited by 17
Comparison of the Prognostic Value of Inflammatory and Nutritional Indices in Nonmetastatic Renal Cell Carcinoma
Makino, T., Izumi, K., Iwamoto, H., Kadomoto, S., Kadono, Y., & Mizokami, A. (2023) · Biomedicines · doi:10.3390/biomedicines11020533 · Cited by 17
Detection of Autoantibodies Against the Acetylcholine Receptor, Evaluation of Commercially Available Methodologies: Fixed Cell-Based Assay, Radioimmunoprecipitation Assay and Enzyme-Linked Immunosorbent Assay
Diogenes, L., Dellavance, A., Baldo, D. C., Gozzi-Silva, S. C., Gomes, K., Prado, M. S., Andrade, L. E. C., & Keppeke, G. D. (2024) · Journal of Neuromuscular Diseases · doi:10.3233/jnd-230210 · Cited by 17
Human Chorionic Gonadotropin Stimulation Test in Prepubertal Children with Micropenis Can Accurately Predict Leydig Cell Function in Pubertal or Postpubertal Adolescents
Ishii, T., Matsuo, N., Sato, S., Ogata, T., Tamai, S., Anzo, M., Kamimaki, T., Sasaki, G., Inokuchi, M., Hori, N., et al. (2015) · Hormone Research in Paediatrics · doi:10.1159/000439234 · Cited by 17
Quantitative Tc-99m DTPA renal transplant scintigraphy predicts graft survival in the very early postoperative period
Gupta, S. K., LEWIS, G. W., Rogers, K., & Attia, J. (2012) · Nuclear Medicine Communications · doi:10.1097/mnm.0b013e328359db96 · Cited by 17
Utility of contrast-enhanced ultrasound with perflubutane for diagnosing the macroscopic type of small nodular hepatocellular carcinomas
Tada, T., Kumada, T., Toyoda, H., Ito, T., Sone, Y., Kaneoka, Y., Maeda, A., Okuda, S., Otobe, K., & Takahashi, K. P. (2014) · European Radiology · doi:10.1007/s00330-014-3254-2 · Cited by 17
Validation of normalized truncated navicular height as a clinical assessment measure of static foot posture to determine flatfoot in children and adolescents: A cross sectional study
Aboelnasr, E. A., Hegazy, F. A., Zaghloul, A. A. Z., Eltalawy, H. A., & Abdelazim, F. H. (2018) · The Foot · doi:10.1016/j.foot.2018.05.001 · Cited by 17
The Value of Pepsinogen in GC Screening: A Systematic Review and Meta-Analysis
Liu, L., Lang, J., Jin, Y., Chen, Y., Chang, W., Yao, Y., & Yu, J. (2019) · Gastroenterology Research and Practice · doi:10.1155/2019/7087232 · Cited by 17
A risk scoring system for predicting Streptococcus suis hearing loss: A 13-year retrospective cohort study
Rayanakorn, A., Katip, W., Goh, B. H., Oberdorfer, P., & Lee, L. (2020) · PLoS ONE · doi:10.1371/journal.pone.0228488 · Cited by 18
Diagnostic utility of measuring serum amyloid A with a latex agglutination turbidimetric immunoassay in bovine mastitis: Comparison with haptoglobin and alpha 1 acid glycoprotein
OTSUKA, M., SUGIYAMA, M., Ito, T., TSUKANO, K., Oikawa, S., & Suzuki, K. (2020) · Journal of Veterinary Medical Science · doi:10.1292/jvms.20-0550 · Cited by 17
Validation of the parent version of the Strengths and Difficulties Questionnaire (SDQ) to screen mental health problems among school-age children in Mongolia
Aoki, A., Ganchimeg, T., Nyam, N., Zuunnast, K., Gundegmaa, L., Bat-Erdene, S., Munkhbaatar, B., Mori, R., Kikuchi, A., Soya, H., et al. (2021) · BMC Psychiatry · doi:10.1186/s12888-021-03218-x · Cited by 18
MR Thermometry Accuracy and Prospective Imaging-Based Patient Selection in MR-Guided Hyperthermia Treatment for Locally Advanced Cervical Cancer
VilasBoas‐Ribeiro, I., Curto, S., van Rhoon, G. C., Franckena, M., & Paulides, M. M. (2021) · Cancers · doi:10.3390/cancers13143503 · Cited by 17
Identifying the best predictive diagnostic criteria for psoriasis in children (< 18 years): a UK multicentre case–control diagnostic accuracy study (DIPSOC study)*
Burden‐Teh, E., Murphy, R., Gran, S., Nijsten, T. E. C., Hughes, C., Abdul‐Wahab, A., Bewley, A., Burrows, N., Darné, S., Gach, J. E., et al. (2021) · British Journal of Dermatology · doi:10.1111/bjd.20689 · Cited by 20
Validation of the Revised Quick Cognitive Screening Test
Mate-Kole, C. C., Conway, J. M., Catayong, K., Bieu, R. K., Sackey, N. A., Wood, R. M., & Fellows, R. P. (2009) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2009.02.007 · Cited by 17
Comparing HbA1c, fasting and 2-h plasma glucose for screening for abnormal glucose regulation in patients undergoing coronary angiography
Wang, J., Lee, I., Lee, W., Lin, S., Fu, C., Lee, W.-L., Liang, K., & Sheu, W. H. (2014) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2014-0860 · Cited by 17
Characterization of Adulterated Milk by Two-Dimensional Infrared Correlation Spectroscopy
Yang, R., Zhang, W. Y., Yang, Y., Wu, Z., Dong, G., & Du, Y. H. (2014) · Analytical Letters · doi:10.1080/00032719.2014.915406 · Cited by 17
The sensitivity and specificity of the Falls Efficacy Scale and the Activities-specific Balance Confidence Scale for hemiplegic stroke patients
Park, E., Lee, Y., & Choi, Y.-I. (2018) · Journal of Physical Therapy Science · doi:10.1589/jpts.28.741 · Cited by 17
5-Aminolevulinic-acid-based fluorescence spectroscopy and conventional colposcopy for in vivo detection of cervical pre-malignancy
Vansevičiūtė-Petkevičienė, R., Venius, J., Žukovskaja, O., Kanopienė, D., Letautienė, S. R., & Rotomskis, R. (2015) · BMC Women s Health · doi:10.1186/s12905-015-0191-4 · Cited by 16
The rCAST score is useful for estimating the neurological prognosis in pediatric patients with post-cardiac arrest syndrome before ICU admission: External validation study using a nationwide prospective registry
Yasuda, Y., Nishikimi, M., Matsui, K., Numaguchi, A., Nishida, K., Emoto, R., Matsui, S., & Matsuda, N. (2021) · Resuscitation · doi:10.1016/j.resuscitation.2021.09.025 · Cited by 16
Association of alignment variables, posteromedial tibial cartilage wear and anterior cruciate ligament insufficiency in participants with varus knee osteoarthritis: a cross-sectional study
Mortazavi, S. M. J., & Vosoughi, F. (2022) · International Orthopaedics · doi:10.1007/s00264-022-05358-5 · Cited by 16
Discrimination in the clinical diagnosis between patients with schizophrenia and healthy controls using eye movement and cognitive functions
Okazaki, K., Miura, K., Matsumoto, J., Hasegawa, N., Fujimoto, M., Yamamori, H., Yasuda, Y., Makinodan, M., & Hashimoto, R. (2023) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.13553 · Cited by 17
Physical activity as a predictor of activities of daily living in older adults: a longitudinal study in China
Wang, L.-Y., Chen, H.-X., Zhu, H., Hu, Z., Zhou, C.-F., & Hu, X. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1444119 · Cited by 16
Post-transplant Renal Function and Cardiovascular Events Are Closely Associated With the Aortic Calcification Index in Renal Transplant Recipients
Imanishi, K., Hatakeyama, S., Yamamoto, H., Okamoto, A., Imai, A., Yoneyama, T., Hashimoto, Y., Koie, T., Fujita, T., Murakami, R., et al. (2014) · Transplantation Proceedings · doi:10.1016/j.transproceed.2013.09.039 · Cited by 16
Performance of HbA1c and Fasting Plasma Glucose in Screening for Diabetes in Patients Undergoing Coronary Angiography
Wang, J., Lee, I., Lee, W., Lin, S., Fu, C., Ting, C.-T., Lee, W.-L., Liang, K., & Sheu, W. H. (2012) · Diabetes Care · doi:10.2337/dc12-1434 · Cited by 16
A five-item screening version of the Eating Disorder Inventory (EDI-3)
Friborg, O., Clausen, L., & Rosenvinge, J. H. (2013) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2013.05.004 · Cited by 16
Relationship between Grooming Performance and Motor and Cognitive Functions in Stroke Patients with Receiver Operating Characteristic Analysis
Fujita, T., Sato, A., Tsuchiya, K., Ohashi, T., Yamane, K., Yamamoto, Y., Iokawa, K., Ohira, Y., Otsuki, K., & Tozato, F. (2017) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2017.06.054 · Cited by 16
Four Square Step Test With Foam Is More Accurate Than Those Without Foam for Discriminating Between Older Adults With and Without Fall History
Mathurapongsakul, P., & Siriphorn, A. (2018) · Journal of Aging and Physical Activity · doi:10.1123/japa.2017-0363 · Cited by 16
Elevated Expression of Transforming Acidic Coiled-Coil Containing Protein 3 (TACC3) Is Associated With a Poor Prognosis in Osteosarcoma
Matsuda, K., Miyoshi, H., Hiraoka, K., Hamada, T., Nakashima, K., Shiba, N. N., & Ohshima, K. (2018) · Clinical Orthopaedics and Related Research · doi:10.1097/corr.0000000000000379 · Cited by 16
Symphysis-fundal height to identify large-for-gestational-age and macrosomia: a meta-analysis
Goto, E. (2019) · Journal of Obstetrics and Gynaecology · doi:10.1080/01443615.2019.1673713 · Cited by 15
Pinch strength is associated with the prevalence of mild cognitive impairment in patients with cardiovascular disease
Ishihara, K., Izawa, K. P., Kitamura, M., Shimogai, T., Kanejima, Y., Morisawa, T., & Shimizu, I. (2020) · Journal of Cardiology · doi:10.1016/j.jjcc.2019.12.009 · Cited by 16
Vestibular Migraine Patients Show Lack of Habituation in Auditory Middle Latency Responses to Repetitive Stimuli: Comparison With Meniere's Disease Patients
Murofushi, T., Goto, F., & Tsubota, M. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.00024 · Cited by 16
Psychometric properties of the short version of the children of alcoholics screening test (CAST-6) among Swedish adolescents
Elgán, T. H., Berman, A. H., Jayaram‐Lindström, N., Hammarberg, A., Jalling, C., & Källmén, H. (2020) · Nordic Journal of Psychiatry · doi:10.1080/08039488.2020.1812000 · Cited by 16
Increased thyroid uptake on 18F-FDG PET/CT is associated with the development of permanent hypothyroidism in stage IV melanoma patients treated with anti-PD-1 antibodies
Frelau, A., Palard-Novello, X., Jali, E., Boussemart, L., Dupuy, A., James, P., Devillers, A., Jeune, F. L., Edeline, J., Lesimple, T., et al. (2020) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-020-02712-7 · Cited by 16
Which hemogram-derived indices might be useful in predicting the clinical outcomes of sepsis patients in the intensive care unit?
Çakır, E. Y., & Turan, İ. Ö. (2021) · Çukurova medical journal (Online)/Çukurova medical journal · doi:10.17826/cumj.856741 · Cited by 16
Developing and validating the personal risk assessment of musculoskeletal disorders (PRAMUD) tool among workers of a steel foundry
Yazdanirad, S., Pourtaghi, G., Raei, M., & Ghasemi, M. (2022) · International Journal of Industrial Ergonomics · doi:10.1016/j.ergon.2022.103276 · Cited by 16
Comparison of CATs, CURB-65 and PMEWS as Triage Tools in Pandemic Influenza Admissions to UK Hospitals: Case Control Analysis Using Retrospective Data
Myles, P. R., Nguyen‐Van‐Tam, J. S., Lim, W. S., Nicholson, K. G., Brett, S. J., Enstone, J. E., McMenamin, J., Openshaw, P., Read, R. C., Taylor, B. L., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034428 · Cited by 16
Prognosis of Elderly Japanese Patients Aged ≥80 Years Undergoing Hemodialysis
Hatakeyama, S., Murasawa, H., Hamano, I., Kusaka, A., Narita, T., Oikawa, M., Noro, D., Hagiwara, K., Ishimura, H., Yoneyama, T., et al. (2013) · The Scientific World JOURNAL · doi:10.1155/2013/693514 · Cited by 16
Development and validation of a new pattern identification scale for Stomach Qi Deficiency
Lee, J. H., Park, J.-W., Ko, S., & Kim, J. (2017) · European Journal of Integrative Medicine · doi:10.1016/j.eujim.2017.11.009 · Cited by 16
Determining a cut-off residual tumor volume threshold for patients with newly diagnosed glioblastoma treated with temozolomide chemoradiotherapy: A multicenter cohort study
Woo, P. Y. M., Ho, J. M. K., Tse, T. P. K., Lam, S. W., Mak, C. H., Chan, D. T. M., Lee, M. W. Y., Wong, S.-T., Chan, K., & Poon, W. S. (2019) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2019.01.022 · Cited by 16
Optimal Hospital and Surgeon Volume Thresholds to Improve 30-Day Readmission Rates, Costs, and Length of Stay for Total Hip Replacement
Chou, Y.-Y., & Tung, Y. (2019) · The Journal of Arthroplasty · doi:10.1016/j.arth.2019.04.049 · Cited by 16
Parallel detection of single nucleotide variants and copy number variants with exome analysis: Validation in a cohort of 700 undiagnosed patients
Suzuki, H., Yamada, M., Uehara, T., Takenouchi, T., & Kosaki, K. (2020) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.61822 · Cited by 16
Evaluation of Modified Estimation of Physiologic Ability and Surgical Stress in Colorectal Carcinoma Surgery
Haga, Y., Wada, Y., Ikenaga, M., TAKEUCHI, H., & Ikejiri, K. (2011) · Diseases of the Colon & Rectum · doi:10.1097/dcr.0b013e3182271a54 · Cited by 16
Co-expression modules construction by WGCNA and identify potential hub genes and regulation pathways of postpartum depression
Deng, Z., Cai, W., Liu, J., Deng, A., Yang, Y., Tu, J., Yuan, C., Xiao, H., & Gao, W. (2021) · Frontiers in Bioscience-Landmark · doi:10.52586/5006 · Cited by 15
Cross-sectional validation of the Rasch-based Depression Screening (DESC) in a mixed sample of patients with mental and somatic diseases
Vehren, T., Boecker, M., Norra, C., Wirtz, M. A., Gauggel, S., & Forkmann, T. (2013) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2013.05.001 · Cited by 15
Comparison of serological techniques for the diagnosis of equine infectious Anemia in an endemic area of Argentina
Espasandin, A. G., Cipolini, M. F., Forletti, A., Díaz, S., Soto, J. A., Martínez, D. E., Storani, C. A., Monzón, N. M., Beltrame, J. I., Lucchesi, E., et al. (2021) · Journal of Virological Methods · doi:10.1016/j.jviromet.2021.114101 · Cited by 15
The Reliability and Validity of the Mandarin Chinese Version of the Vocal Fatigue Index: Preliminary Validation
Chan, R. W., Lee, Y. H., Liao, C., Jen, J. H., Wu, C., Lin, F., & Wang, C. (2022) · Journal of Speech Language and Hearing Research · doi:10.1044/2022_jslhr-21-00492 · Cited by 15
PUMA screening tool to detect COPD in high-risk patients in Chinese primary care–A validation study
Au-Doung, P. L. W., Wong, C. K. M., Chan, D. C. C., Chung, J. W. H., Wong, S. Y. S., & Leung, M. K. W. (2022) · PLoS ONE · doi:10.1371/journal.pone.0274106 · Cited by 20
Surgical Versus Conservative Management for Treating Unstable Atlas Fractures: A Multicenter Study
Shin, J. J., Kim, K.-R., Shin, J., Kang, J., Lee, H. J., Kim, T. W., Hong, J. T., Kim, S. W., & Ha, Y. S. (2022) · Neurospine · doi:10.14245/ns.2244352.176 · Cited by 15
Characterizing NOx emissions from diesel trucks with tampered aftertreatment systems and its implications for identifying high emitters
Tian, M., He, L., Peng, D., Fu, M., Ma, S., Mu, J., Yu, Q., Wang, J., Yin, H., & Wang, J. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.170378 · Cited by 15
Absolute beat‐to‐beat variability and instability parameters of ECG intervals: biomarkers for predicting ischaemia‐induced ventricular fibrillation
Sarusi, A., Rárosi, F., Szűcs, M., Csík, N., Farkas, A. S., Papp, J. G., Varró, A., Forster, T., Curtis, M. J., & Farkas, A. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12579 · Cited by 15
Diagnostic value of maternal anthropometric measurements for predicting low birth weight in developing countries: a meta-analysis.
Goto, E. (2015) · PubMed · doi:10.6133/apjcn.2015.24.2.05 · Cited by 15
New Computer-Aided Diagnosis of Dementia Using Positron Emission Tomography: Brain Regional Sensitivity-Mapping Method
Kakimoto, A., Kamekawa, Y., Ito, S., Yoshikawa, E., Okada, H., Nishizawa, S., Minoshima, S., & Ouchi, Y. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025033 · Cited by 15
PTH inhibition rate is useful in the detection of early-stage primary hyperparathyroidism
Zhao, L., Zhang, M.-J., Zhao, H., Sun, L., Li, J.-L., Tao, B., Wang, W., Ning, G., & Liu, J. (2011) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2011.03.142 · Cited by 15
Antipsychotic Response in the First Week Predicts Later Efficacy
Giegling, I., Porcelli, S., Balzarro, B., Andrisano, C., Schäfer, M. K.-H., Möller, H., Rujescu, D., & Serretti, A. (2012) · Neuropsychobiology · doi:10.1159/000337739 · Cited by 15
Screening Accuracy and Clinical Application of the Brief Infant-Toddler Social and Emotional Assessment (BITSEA)
Kruizinga, I., Jansen, W., Mieloo, C. L., Carter, A. S., & Raat, H. (2013) · PLoS ONE · doi:10.1371/journal.pone.0072602 · Cited by 15
In Vitro Drug Sensitivity Tests to Predict Molecular Target Drug Responses in Surgically Resected Lung Cancer
Miyazaki, R., Anayama, T., Hirohashi, K., Okada, H., Kume, M., & Orihashi, K. (2016) · PLoS ONE · doi:10.1371/journal.pone.0152665 · Cited by 15
Intra-abdominal and subcutaneous abdominal fat as predictors of cardiometabolic risk in a sample of Mexican children
González-Álvarez, C., Ramos-Ibáñez, N., Azprioz-Leehan, J., & Ortiz-Hernández, L. (2017) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2017.28 · Cited by 15
Plethysmography variability index for prediction of fluid responsiveness during graded haemorrhage and transfusion in sevoflurane-anaesthetized mechanically ventilated dogs
Endo, Y., Kawase, K., Miyasho, T., Sano, T., YAMASHITA, K., & Muir, W. W. (2017) · Veterinary Anaesthesia and Analgesia · doi:10.1016/j.vaa.2017.07.007 · Cited by 15
Development and validation of an environmental heat strain risk assessment (EHSRA) index using structural equation modeling based on empirical relations
Yazdanirad, S., Golbabaei, F., Foroushani, A. R., Monazzam, M. R., & Dehghan, H. (2020) · Environmental Health and Preventive Medicine · doi:10.1186/s12199-020-00894-1 · Cited by 14
Predictors of activities of daily living at discharge in elderly patients with heart failure with preserved ejection fraction
Kitamura, M., Izawa, K. P., Ishihara, K., Yaekura, M., Nagashima, H., Yoshizawa, T., & Okamoto, N. (2020) · Heart and Vessels · doi:10.1007/s00380-020-01718-6 · Cited by 15
Rugby league ball carrier injuries: The relative importance of tackle characteristics during the European Super League
Hopkinson, M., Nicholson, G., Weaving, D., Hendricks, S., Fitzpatrick, A. C., Naylor, A. S., Robertson, C. M., Beggs, C. B., & Jones, B. L. (2020) · European Journal of Sport Science · doi:10.1080/17461391.2020.1853817 · Cited by 15
Development and Implementation of Autoverification Rules for ELISA Results of HBV Serological Markers
Li, J., Cheng, B., Yang, L., Zhao, Y. H., Pan, M., Zheng, G., Xu, X., Hu, J., Xiao, T., & Cai, Y. (2015) · SLAS TECHNOLOGY · doi:10.1177/2211068215601612 · Cited by 15
Caspase-cleaved fragments of cytokeratin 18 in patients with chronic hepatitis B
Eren, F., Yilmaz, Y. N., Köse, Ş., Özdemir, F. T., Yönal, O., Kurt, R., Ozdogan, O. C., & Avşar, E. (2010) · Clinica Chimica Acta · doi:10.1016/j.cca.2010.08.035 · Cited by 15
Elevated Levels of Angiopoietin-2 as a Biomarker for Respiratory Failure After Cardiac Surgery
Uchida, T., Ito, H., Yamamoto, H., Ohno, N., Asahara, M., Yamada, Y., Yamaguchi, O., Tomita, M., & Makita, K. (2014) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2014.03.004 · Cited by 16
The Predictive Value of Genetic Analyses in the Diagnosis of Tetrahydrobiopterin (BH4)-Responsiveness in Chinese Phenylalanine Hydroxylase Deficiency Patients
Zhu, T., Ye, J., Han, L., Qiu, W., Zhang, H., Liang, L., & Gu, X. (2017) · Scientific Reports · doi:10.1038/s41598-017-06462-y · Cited by 15
Appropriate Body Mass Index and Waist-hip Ratio Cutoff Points for Overweight and Obesity in Adults of Northeast China.
Yu, Q., Pang, B., Liu, R., Rao, W., Zhang, S., & Yu, Y. (2017) · Europe PMC (PubMed Central) · Cited by 15
Tumor Hypoxia Detected by 18F-fluoromisonidazole Positron Emission Tomography (FMISO PET) as a Prognostic Indicator of Radiotherapy (RT)
Tachibana, I., Nishimura, Y., Hanaoka, K., Inada, M., Fukuda, K., Tatebe, H., Ishikawa, K., Nakamatsu, K., Kanamori, S., & Hosono, M. (2018) · Anticancer Research · doi:10.21873/anticanres.12415 · Cited by 15
Measuring the quality of maternal and care processes at the time of delivery in sub-Saharan Africa: development and validation of a short index
Tripathi, V., Stanton, C., Strobino, D. M., & Bartlett, L. (2019) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-019-2281-z · Cited by 15
Identification of diagnostic markers for major depressive disorder by cross-validation of data from whole blood samples
Wang, H., Zhang, M., Xie, Q., Yu, J. M., Yan, Q., & Yue, Q. (2019) · PeerJ · doi:10.7717/peerj.7171 · Cited by 15
Importancia del cálculo de la sensibilidad, la especificidad y otros parámetros estadísticos en el uso de las pruebas de diagnóstico clínico y de laboratorio
Vizcaíno, G. (2017) · Medicina y Laboratorio · doi:10.36384/01232576.34 · Cited by 15
Minimal residual disease in high-risk neuroblastoma shows a dynamic and disease burden-dependent correlation between bone marrow and peripheral blood
Lin, K. S., Uemura, S., Thwin, K. K. M., Nakatani, N., Ishida, T., Yamamoto, N., Tamura, A., Saito, A., Mori, T., Hasegawa, D., et al. (2021) · Translational Oncology · doi:10.1016/j.tranon.2021.101019 · Cited by 15
Predicting risk factors for varicella zoster virus infection and postherpetic neuralgia after hematopoietic cell transplantation using ordered logistic regression analysis
Kanbayashi, Y., Matsumoto, Y., Kuroda, J., Kobayashi, T., Horiike, S., Hosokawa, T., & Taniwaki, M. (2016) · Annals of Hematology · doi:10.1007/s00277-016-2883-8 · Cited by 15
Novel physical performance-based models for activities of daily living disability prediction among Chinese older community population: a nationally representative survey in China
Zhang, L., Chen, Y., Liu, J., Yu, Y., Cui, H., Chen, Q., Chen, K., Yang, C., & Yang, Y. (2022) · BMC Geriatrics · doi:10.1186/s12877-022-02905-y · Cited by 15
Change of neutrophil-to-monocyte ratio to stratify the mortality risk of adult patients with trauma in the intensive care units
Tsai, C., Liu, H.-T., Hsieh, T.-M., Huang, C.-Y., Chou, S.-E., Su, W.-T., Li, C., Hsu, S.-Y., & Hsieh, C. (2022) · Formosan Journal of Surgery · doi:10.4103/fjs.fjs_88_22 · Cited by 14
Bulk and single-cell transcriptome analyses of islet tissue unravel gene signatures associated with pyroptosis and immune infiltration in type 2 diabetes
Song, Y., He, C., Jiang, Y., Yang, M., Zhao, X., Yuan, L., Zhang, W., & Xu, Y. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1132194 · Cited by 15
Noninvasive Raman spectroscopy for the detection of rice bacterial leaf blight and bacterial leaf streak
Ji, X., Xue, J., Shi, J., Wang, W., Zhang, X., Wang, Z., Lu, W., Liu, J., Fu, Y. V., & Xu, N. (2024) · Talanta · doi:10.1016/j.talanta.2024.126962 · Cited by 14
Which Part of a Short, Global Risk Assessment, the Risk Instrument for Screening in the Community, Predicts Adverse Healthcare Outcomes?
Ó’Caoimh, R., Fitzgerald, C., Cronin, U. M., Svendrovski, A., Gao, Y., Healy, E., O’Connell, E., O’Keeffe, G., O’Herlihy, E. A., Weathers, E., et al. (2015) · Journal of Aging Research · doi:10.1155/2015/256414 · Cited by 14
Strategies for digital mammography interpretation in a clinical patient population
van den Biggelaar, F. J. H. M., Kessels, A. G. H., van Engelshoven, J. M. A., & Flobbe, K. (2009) · International Journal of Cancer · doi:10.1002/ijc.24632 · Cited by 14
An individual scoring system for the prediction of postpartum anaemia
Allary, J., Soubirou, J.-F., Michel, J., Amiel, I., Silins, V., Brasher, C., Oury, J., Nivoche, Y., & Dahmani, S. (2012) · Annales Françaises d Anesthésie et de Réanimation · doi:10.1016/j.annfar.2012.11.002 · Cited by 14
Image analysis of the nuclear characteristics of emerin protein and the correlation with nuclear grooves and intranuclear cytoplasmic inclusions in lung adenocarcinoma
Kobayashi, S., Saio, M., Fukuda, T., Kimura, K., Hirato, J., & Oyama, T. (2018) · Oncology Reports · doi:10.3892/or.2018.6848 · Cited by 14
Evaluating the role of RAD52 and its interactors as novel potential molecular targets for hepatocellular carcinoma
Li, P., Xu, Y., Zhang, Q., Li, Y., Jia, W., Wang, X., Xie, Z., Liu, J., Zhao, D. H., Shao, M., et al. (2019) · Cancer Cell International · doi:10.1186/s12935-019-0996-6 · Cited by 14
Substantial clinical benefit, responsiveness, and sensitivity to change of three common outcome measures following shoulder arthroplasty
Razmjou, H., Rahnama, L., Holtby, R. M., Drosdowech, D. S., & Richards, R. R. (2020) · SAGE Open Medicine · doi:10.1177/2050312120946218 · Cited by 14
Serum iron concentration is a useful biomarker for assessing the level of inflammation that causes systemic symptoms in bovine acute mastitis similar to plasma haptoglobin
TSUKANO, K., & Suzuki, K. (2020) · Journal of Veterinary Medical Science · doi:10.1292/jvms.20-0388 · Cited by 14
The association between social emotional development and symptom presentation in autism spectrum disorder
Reid, K., Sacrey, L.-A. R., Zwaigenbaum, L., Raza, S., Brian, J. A., Smith, I. M., Bryson, S. E., Armstrong, V. L., Roberts, W., Szatmári, P., et al. (2020) · Development and Psychopathology · doi:10.1017/s0954579420000711 · Cited by 16

Authors: Akobeng, A. K.
Corresponding author: Akobeng, Anthony K
ORCID: Akobeng, Anthony K
Venue: Acta Paediatrica
Publisher: Wiley
Published: 2007-03-21
Volume: 96
Issue: 5
Pages: 644-647
ISSN: 0365-1436 (ISSN-L)
0803-5253
1651-2227
DOI: 10.1111/j.1651-2227.2006.00178.x
OpenAlex: W2073887351
Cited by: 1,882
References: 17
Citations by year: 2026: 53 · 2025: 95 · 2024: 135 · 2023: 138 · 2022: 167 · 2021: 156 · 2020: 131 · 2019: 116 · 2018: 102 · 2017: 120 · 2016: 113 · 2015: 117 · 2014: 117 · 2013: 98 · 2012: 76
FWCI: 29.05
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Acta Paediatrica (publishedVersion)
PubMed (publishedVersion)
Topics: Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Epidemiology
Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
Health Sciences › Health Professions › Medical Laboratory Technology › Clinical Laboratory Practices and Quality Control
Keywords: receiver operating characteristic, diagnostic accuracy, cut-point selection, sensitivity, specificity, Youden index, area under the ROC curve, diagnostic test comparison
MeSH terms: C-Reactive Protein, Calcitonin, Humans, Leukocyte Count, Protein Precursors, ROC Curve, Sensitivity and Specificity, Shock, Septic

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Understanding diagnostic tests 3: receiver operating characteristic curves

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks