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The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis
Abstract
The new stereological methods for correct and efficient sampling and sizing of cells and other particles are reviewed. There is a hierarchy of methods starting from the simplest where even the microscopic magnification may be unknown to the most complex where typically both section thickness and the magnification must be known. Optical sections in suitably modified microscopes can be used to improve the ease and speed with which even the most demanding of these methods are performed. The methods are illustrated by practical examples of applications to a wide range of histological entities including synapses, neurons and cancer cells, glomerular corpuscles and ovarian follicles.
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Research works printed but not linked: 34
- Bendtsen T. F., 1988, Unbiased estimation of particle number using sections – a historical perspective with special reference to the stereology of glomeruli, J. Microsc.
- 10.1007/BF00412629 · doi:10.1007/bf00412629
- 10.1016/0165-0270(86)90112-3 · DOI · Paper page
- 10.1016/0304-3940(88)90180-2 · DOI
- 10.1007/BF00218208 · DOI
- 10.1002/cne.902660213 · DOI
- Cruz‐Orive L.‐M., 1987, Particle number can be estimated using a disector of unknown thickness: The selector, J. Microsc., 145, 121
- 10.3109/10520298309066814 · doi:10.3109/10520298309066814
- Diem K., 1970, Documenta Geigy. Scientific Tables
- 10.1111/j.1365-2818.1986.tb02764.x · DOI · Paper page
- Gundersen H. J. G., 1988, The nucleator. In press, J. Microsc., 150
- 10.1111/j.1365-2818.1983.tb04256.x · doi:10.1111/j.1365-2818.1983.tb04256.x
- 10.1111/j.1365-2818.1985.tb02607.x · DOI · Paper page
- 10.1111/j.1365-2818.1987.tb02837.x · DOI · Paper page
- Gundersen H. J. G., 1987, Estimation of moments of size distributions of arbitrary particles, Acta. Stereol., 6, 197
- 10.1111/j.1699-0463.1988.tb05320.x · DOI · Paper page
- 10.1007/BF00695228 · doi:10.1007/bf00695228
- Howard V., 1986, Quantitative Image Analysis in Cancer Cytology and Histology, 245
- 10.1111/j.1365-2818.1985.tb02613.x · DOI
- 10.1111/j.1365-2818.1982.tb00322.x · DOI
- Jensen E. B. KÊIu K.&Gundersen H. J. G.:On stereological estimation of moment measures. In: Research Report No. 175 1988 pp.1–20.Department of Theoretical Statistics University of Aarhus Aarhus.
- Jolly G. M.:Sampling of large objects. In:Cormack R. M. Patil G. P.&Robson D. S.(Eds.): Sampling Biological Populations.Int. Co‐operat. Publish. House Maryland1979 pp.193–201.
- 10.1111/j.1365-2818.1988.tb04603.x · DOI · Paper page
- 10.1161/01.RES.57.5.794 · DOI · Paper page
- 10.1007/BF00713520 · doi:10.1007/bf00713520
- 10.1007/BF02889949 · doi:10.1007/bf02889949
- Nielsen K., 1988, Stereological estimation of mean nuclear volume in prostatic cancer, the reproducibility and the possible value of estimations on repeated biopsies in the course of disease, J. Microsc
- Nielsen K., 1988, Stereological estimates of nuclear volume in non‐invasive bladder tumors (Ta) correlated with the recurrence pattern, J. Urol.
- 10.1111/j.1365-2559.1985.tb02831.x · doi:10.1111/j.1365-2559.1985.tb02831.x
- 10.1111/j.1365-2818.1988.tb04582.x · DOI · Paper page
- 10.1364/JOSA.58.000661 · doi:10.1364/josa.58.000661
- Sandau K., 1987, How to estimate the area of a surface using a spatial grid, Acta Stereologica, 6, 31
- 10.1111/j.1365-2818.1984.tb02501.x · DOI · Paper page
- SØRensen F. B.:Stereological estimation of nuclear volume in benign melanocytic lesions and cutaneous malignant melanomas.Submitted1989a. · doi:10.1097/00000372-198912000-00002
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Metadata
- Authors
- Gundersen, H. J. G., Bagger, P., Bendtsen, T. F., Evans, S. M., Korbo, L., Marcussen, N., MØLler, A., Nielsen, K., Nyengaard, J. R., Pakkenberg, B., SØRensen, F. B., Vesterby, A., & West, M. J.
- Venue
- APMIS
- Publisher
- Wiley
- Published
- 1988-07
- Volume
- 96
- Issue
- 7-12
- Pages
- 857-881
- ISSN
- 0903-4641 (ISSN-L)
- 1600-0463
- OpenAlex
- W2105382539
- Cited by
- 2,478
- References
- 0
- FWCI
- 47.33
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. https://app.cochat.ai/papers/10.1111/j.1699-0463.1988.tb00954.x
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- Gundersen, H. J. G., Bagger, P., Bendtsen, T. F., Evans, S. M., Korbo, L., Marcussen, N., MØLler, A., Nielsen, K., Nyengaard, J. R., Pakkenberg, B., SØRensen, F. B., Vesterby, A., & West, M. J. (1988). The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. APMIS. https://doi.org/10.1111/j.1699-0463.1988.tb00954.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.