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The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis

Gundersen, H. J. G., Bagger, P., Bendtsen, T. F., Evans, S. M., Korbo, L., Marcussen, N., MØLler, A., Nielsen, K., Nyengaard, J. R., Pakkenberg, B., SØRensen, F. B., Vesterby, A., West, M. J.·1988·APMIS

Abstract

The new stereological methods for correct and efficient sampling and sizing of cells and other particles are reviewed. There is a hierarchy of methods starting from the simplest where even the microscopic magnification may be unknown to the most complex where typically both section thickness and the magnification must be known. Optical sections in suitably modified microscopes can be used to improve the ease and speed with which even the most demanding of these methods are performed. The methods are illustrated by practical examples of applications to a wide range of histological entities including synapses, neurons and cancer cells, glomerular corpuscles and ovarian follicles.

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Research works printed but not linked: 34

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Metadata

Authors
Gundersen, H. J. G., Bagger, P., Bendtsen, T. F., Evans, S. M., Korbo, L., Marcussen, N., MØLler, A., Nielsen, K., Nyengaard, J. R., Pakkenberg, B., SØRensen, F. B., Vesterby, A., & West, M. J.
Venue
APMIS
Publisher
Wiley
Published
1988-07
Volume
96
Issue
7-12
Pages
857-881
ISSN
  • 0903-4641 (ISSN-L)
  • 1600-0463
OpenAlex
W2105382539
Cited by
2,478
References
0
FWCI
47.33
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. https://app.cochat.ai/papers/10.1111/j.1699-0463.1988.tb00954.x
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Gundersen, H. J. G., Bagger, P., Bendtsen, T. F., Evans, S. M., Korbo, L., Marcussen, N., MØLler, A., Nielsen, K., Nyengaard, J. R., Pakkenberg, B., SØRensen, F. B., Vesterby, A., & West, M. J. (1988). The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. APMIS. https://doi.org/10.1111/j.1699-0463.1988.tb00954.x

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