Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 169

The DOI matches its Crossref record.

Clinical effectiveness of an acellular dermal regenerative tissue matrix compared to standard wound management in healing diabetic foot ulcers: a prospective, randomised, multicentre study

Reyzelman, Alexander, Crews, Ryan T, Moore, John C, Moore, Lily, Mukker, Jagpreet S, Offutt, Stephen, Tallis, Arthur, Turner, William B, Vayser, Dean, Winters, Christopher, Armstrong, David G·2009·International Wound Journal
DOI 10.1111/j.1742-481x.2009.00585.x
Open this paper in CoChat — free account

Abstract

This 12‐week, prospective, randomised, controlled multi‐centre study compared the proportion of healed diabetic foot ulcers and mean healing time between patients receiving acellular matrix (AM) (study group) and standard of care (control group) therapies. Eighty‐six patients were randomised into study (47 patients) and control (39 patients) groups. No significant differences in demographics or pre‐treatment ulcer data were calculated. Complete healing and mean healing time were 69·6% and 5·7 weeks, respectively, for the study group and 46·2% and 6·8 weeks, respectively, for the control group. The proportion of healed ulcers between the groups was statistically significant ( P = 0·0289), with odds of healing in the study group 2·7 times higher than in the control group. Kaplan–Meier survivorship analysis for time to complete healing at 12 weeks showed a significantly higher non healing rate ( P = 0·015) for the control group (53·9%) compared with the study group (30·4%). After adjusting for ulcer size at presentation, which was a statistically significant covariate ( P = 0·0194), a statistically significant difference in non healing rate between groups was calculated ( P = 0·0233), with odds of healing 2·0 times higher in the study versus control group. This study supports the use of single‐application AM therapy as an effective treatment of diabetic, neuropathic ulcers.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1111/j.1742-481x.2009.00585.x

Cites

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

No references could be resolved yet.

Research works printed but not linked: 62

  1. 10.2337/diacare.27.5.1047 · DOI · Paper page
  2. 10.1001/jama.293.2.217 · DOI
  3. 10.1056/NEJMcp032966 · DOI · Paper page
  4. 10.1093/ptj/83.1.17 · DOI
  5. 10.1080/09638280010005585 · DOI
  6. 10.1016/S0190-9622(94)70134-2 · DOI
  7. 10.1016/S1056-8727(00)00133-1 · DOI
  8. 10.1002/dmrr.216 · DOI
  9. Vileikyte L, 2000, Psychological/behavioral issues in diabetic neuropathic foot ulceration, Wounds, 12, 43B
  10. 10.2337/diacare.22.3.382 · DOI
  11. 10.1016/S0149-2918(98)80044-1 · DOI
  12. Armstrong DG, 1998, Who is at risk for diabetic foot ulceration?, Clin Podiatr Med Surg, 15, 11, 10.1016/S0891-8422(23)01025-X · DOI
  13. 10.7547/87507315-87-7-321 · DOI
  14. 10.1002/dme.1996.13.s1.6 · DOI · Paper page
  15. Brigido SA, 2004, Effective management of major lower extremity wounds using an acellular regenerative tissue matrix: a pilot study, Orthopedics, 27, s145, 10.3928/0147-7447-20040102-14 · DOI · Paper page
  16. 10.1097/00000637-199811000-00009 · DOI
  17. 10.1097/00005537-200109000-00007 · DOI
  18. 10.1001/archfaci.5.1.40 · DOI
  19. 10.1001/archfacial.qoa00016.38 · DOI
  20. 10.1001/archfaci.1.3.195 · DOI
  21. 10.1097/00005537-200111000-00024 · DOI
  22. 10.1097/00006534-200102000-00040 · DOI
  23. 10.1097/00006534-200102000-00038 · DOI
  24. 10.1016/S0030-6665(05)70165-1 · DOI
  25. 10.1001/archotol.124.11.1201 · DOI
  26. 10.1097/01.PRS.0000047444.70346.63 · DOI
  27. 10.1055/s-2008-1064339 · DOI
  28. 10.1016/S0161-6420(99)90488-8 · DOI
  29. 10.1097/00002341-200005000-00010 · DOI
  30. 10.1097/00005537-200111000-00007 · DOI
  31. 10.1001/archfaci.5.1.109 · DOI
  32. Terino EO, 2001, Alloderm acellular dermal graft: applications in aesthetic soft‐tissue augmentation, Clin Plast Surg, 28, 83, 10.1016/S0094-1298(20)32341-5 · DOI
  33. 10.1097/01.sap.0000100895.41198.27 · DOI
  34. 10.1016/S0002-9610(02)00916-9 · DOI
  35. Guy JS, 2003, Early one‐stage closure in patients with abdominal compartment syndrome: fascial replacement with human acellular dermis and bipedicle flaps, Am Surg, 69, 1025, 10.1177/000313480306901202 · DOI
  36. 10.1097/00005537-200202000-00006 · DOI
  37. 10.2310/7070.2002.34423 · DOI
  38. 10.1097/00000637-199910000-00006 · DOI
  39. 10.1097/00004630-199703000-00010 · DOI
  40. 10.1016/S0305-4179(00)00096-6 · DOI
  41. 10.1097/00004630-199711000-00005 · DOI
  42. 10.1097/00004630-199811000-00012 · DOI
  43. Tsai CC, 1999, The use of composite acellular allodermis‐ultrathin autograft on joint area in major burn patients – one year follow‐up, Kaohsiung J Med Sci, 15, 651
  44. 10.1016/0305-4179(95)93866-I · DOI · Paper page
  45. 10.1097/00004630-199603000-00006 · DOI
  46. 10.1111/j.1742-4801.2005.00099.x · DOI · Paper page
  47. 10.1097/01.ASW.0000323532.98003.26 · DOI · Paper page
  48. 10.1016/S1067-2516(96)80125-6 · DOI
  49. 10.1086/511036 · DOI · Paper page
  50. 10.1111/j.1742-481X.2006.00209.x · DOI
  51. Eyre‐Brook AL, 1984, The periosteum: its function reassessed, Clin Orthop Relat Res, 189, 300
  52. 10.1097/00005131-199903000-00006 · DOI
  53. 10.1097/00003086-197411000-00004 · DOI
  54. 10.1016/S0278-2391(99)90336-1 · DOI
  55. 10.1097/00006123-199908000-00025 · DOI
  56. 10.1097/00006534-200103000-00016 · DOI
  57. 10.1902/jop.1998.69.11.1305 · DOI
  58. 10.1097/00007890-199507150-00001 · DOI · Paper page
  59. 10.1001/archfaci.2.2.130 · DOI
  60. 10.1177/0363546504271500 · DOI
  61. 10.1002/jbm.b.30170 · DOI · Paper page
  62. 10.2337/diacare.22.5.692 · DOI · Paper page

Cited by

Metadata

Authors
Reyzelman, A., Crews, R. T., Moore, J. C., Moore, L., Mukker, J. S., Offutt, S., Tallis, A., Turner, W. B., Vayser, D., Winters, C., & Armstrong, D. G.
Venue
International Wound Journal
Publisher
Wiley
Published
2009-06
Volume
6
Issue
3
Pages
196-208
ISSN
  • 1742-4801
  • 1742-481X
DOI
10.1111/j.1742-481x.2009.00585.x
Cited by
169
References
0
Language
en
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.