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Cited by 252Nitric Oxide and Endothelin EffectsCardiovascular Health and Disease PreventionIon channel regulation and function

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Vasomotion – what is currently thought?

Aalkjær, C., Boedtkjer, D., Matchkov, V.·2011·Acta Physiologica
DOI 10.1111/j.1748-1716.2011.02320.x
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Abstract

This minireview discusses vasomotion, which is the oscillation in tone of blood vessels leading to flowmotion. We will briefly discuss the prevalence of vasomotion and its potential physiological and pathophysiological relevance. We will also discuss the models that have been suggested to explain how a coordinated oscillatory activity of the smooth muscle tone can occur and emphasize the role of the endothelium, the handling of intracellular Ca 2+and the role of smooth muscle cell ion conductances. It is concluded that vasomotion is likely to enhance tissue dialysis, although this concept still requires more experimental verification, and that an understanding at the molecular level for the pathways leading to vasomotion is beginning to emerge.

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Metadata

Authors
Aalkjær, C., Boedtkjer, D., & Matchkov, V.
Affiliations
Aarhus University (DK)
Corresponding author
Aalkjær, C.
ORCID
Venue
Acta Physiologica
Publisher
Wiley
Published
2011-05-27
Volume
202
Issue
3
Pages
253-269
ISSN
  • 1748-1708 (ISSN-L)
  • 1748-1716
DOI
10.1111/j.1748-1716.2011.02320.x
OpenAlex
W1505333444
Cited by
252
References
0
Citations by year
2026: 12 · 2025: 18 · 2024: 15 · 2023: 19 · 2022: 19 · 2021: 18 · 2020: 21 · 2019: 25 · 2018: 18 · 2017: 18 · 2016: 14 · 2015: 14 · 2014: 19 · 2013: 8 · 2012: 9
FWCI
1.44
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Acta Physiologica (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ion channel regulation and function
Keywords
vasomotion, vascular smooth muscle, endothelium, intracellular calcium, ionic conductance
MeSH terms
Animals, Calcium, Cell Communication, Chlorides, Endothelium, Vascular, Humans, Membrane Potentials, Mesenteric Arteries, Models, Biological, Muscle, Smooth, Vascular, Vasomotor System, Gap Junctions, Calcium Signaling

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