The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Singlet Oxygen Sensor Green®: Photochemical Behavior in Solution and in a Mammalian Cell
Abstract
The development of efficient and selective luminescent probes for reactive oxygen species, particularly for singlet molecular oxygen, is currently of great importance. In this study, the photochemical behavior of Singlet Oxygen Sensor Green® (SOSG), a commercially available fluorescent probe for singlet oxygen, was examined. Despite published claims to the contrary, the data presented herein indicate that SOSG can, in fact, be incorporated into a living mammalian cell. However, for a number of reasons, caution must be exercised when using SOSG. First, it is shown that the immediate product of the reaction between SOSG and singlet oxygen is, itself, an efficient singlet oxygen photosensitizer. Second, SOSG appears to efficiently bind to proteins which, in turn, can influence uptake by a cell as well as behavior in the cell. As such, incorrect use of SOSG can yield misleading data on yields of photosensitized singlet oxygen production, and can also lead to photooxygenation‐dependent adverse effects in the system being investigated.
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Cites
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Cited by
Chen, Y.-Z., Wang, Z. U., Wang, H., Lu, J., Yu, S.-H., & Jiang, H.-L. (2017) · Journal of the American Chemical Society · doi:10.1021/jacs.6b12074 · Cited by 801
The detection sensitivity of commonly used singlet oxygen probes in aqueous environments
Entradas, T., Waldron, S., & Volk, M. (2020) · Journal of Photochemistry and Photobiology B: Biology · doi:10.1016/j.jphotobiol.2020.111787 · Cited by 559
Nanoscintillator-Mediated X-ray Inducible Photodynamic Therapy for In Vivo Cancer Treatment
Chen, H., Wang, G. D., Chuang, Y.-J., Zhen, Z., Chen, X., Biddinger, P., Hao, Z., Liu, F., Shen, B., Pan, Z., et al. (2015) · Nano Letters · doi:10.1021/nl504044p · Cited by 381
Zeng, Y., Hu, X., Cai, Z., Qiu, D., Ran, Y., Ding, Y., Shi, J., Cai, X., & Pan, Y. (2024) · Journal of Nanobiotechnology · doi:10.1186/s12951-024-02483-8 · Cited by 48
Debele, T. A., Mekuria, S. L., & Tsai, H.-C. (2017) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2017.01.103 · Cited by 36
Metadata
- Authors
- Gollmer, A., Arnbjerg, J., Blaikie, F. H., Pedersen, B. W., Breitenbach, T., Daasbjerg, K., Glasius, M., & Ogilby, P. R.
- Venue
- Photochemistry and Photobiology
- Publisher
- Wiley
- Published
- 2011-02-22
- Volume
- 87
- Issue
- 3
- Pages
- 671-679
- ISSN
- 0031-8655 (ISSN-L)
- 1751-1097
- OpenAlex
- W1536155243
- Cited by
- 298
- References
- 28
- FWCI
- 6.57
- Type
- journal article
- Language
- en
- Open access
- closed
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- Gollmer, A., Arnbjerg, J., Blaikie, F. H., Pedersen, B. W., Breitenbach, T., Daasbjerg, K., Glasius, M., & Ogilby, P. R. (2011). Singlet Oxygen Sensor Green®: Photochemical Behavior in Solution and in a Mammalian Cell. Photochemistry and Photobiology. https://doi.org/10.1111/j.1751-1097.2011.00900.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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