US Trends in Glycemic Control, Treatment, and Comorbidity Burden in Patients With Diabetes
Open accessAbstract
J Clin Hypertens (Greenwich). 2010;12:826‐832. © 2010 Wiley Periodicals, Inc. This study explored trends over time in diabetes prevalence, glycemic control, and antidiabetic therapy choices among adults (18–64 years) and older adults (≥65 years). Factors that predict diabetes outcomes were explored. The study was cross‐sectional, with data from the 1999 to 2004 National Health and Nutrition Examination Survey. The study group consisted of 1211 persons with self‐reported diabetes. Other information obtained from the study included self‐reported medication for diabetes, hypertension, stroke, heart failure, and health status. The survey also provided examination or laboratory tests of obesity, nephropathy, and glycosylated hemoglobin level. Descriptive and logistic regression analyses were used in the study. The study showed that the proportion of diabetics with good glycemic control increased during the period from 1999 to 2004. However, nearly half of the adults and one third of older adults with diabetes did not reach glycemic control in 2003–2004. Overall, 59% of adults and 46% of older adults were obese. There was a high prevalence of hypertension, heart failure, stroke, and nephropathy among patients with diabetes, especially in older adults. The results indicate a high percentage of poor glycemic control among persons with diabetes. There were also a substantial number of comorbid conditions associated with diabetes.
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More than 35% of individuals with type 2 diabetes are co-diagnosed with ASCVD, HF or CKD.
“Because of the shared pathophysiological mechanisms underpinning the development of type 2 diabetes and cardiorenal conditions, coupled with the micro- and macrovascular consequences of chronic unmitigated hyperglycaemia, more than 35% of individuals with type 2 diabetes are co-diagnosed with atherosclerotic cardiovascular disease (ASCVD), congestive heart failure (HF) or chronic kidney disease (C”
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- Authors
- Shaya, F. T., Yan, X., Lin, P., Simoni‐Wastila, L., Bron, M., Baran, R., & Donner, T. W.
- Affiliations
- University of Maryland, Baltimore (US)
- Tufts Medical Center (US)
- Takeda (United States) (US)
- Johns Hopkins University (US)
- Corresponding author
- Shaya, Fadia T.
- Venue
- The Journal of Clinical Hypertension
- Publisher
- Wiley
- Published
- 2010-10
- Volume
- 12
- Issue
- 10
- Pages
- 826-832
- ISSN
- 1524-6175 (ISSN-L)
- 1751-7176
- PMC
- PMC8673194
- OpenAlex
- W1987005319
- Cited by
- 29
- References
- 28
- Citations by year
- 2024: 4 · 2023: 1 · 2022: 1 · 2021: 2 · 2019: 4 · 2018: 2 · 2016: 2 · 2015: 1 · 2014: 2 · 2013: 5 · 2012: 4
- FWCI
- 2.41
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Clinical Hypertension (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- diabetes mellitus, glycemic control, antidiabetic therapy, comorbidities, diabetes prevalence, older adults, obesity, hypertension, heart failure, stroke, diabetic nephropathy, HbA1c, health status, NHANES
- MeSH terms
- Adolescent, Adult, Aged, Blood Glucose, Cross-Sectional Studies, Diabetes Mellitus, Female, Humans, Hypoglycemic Agents, Male, Middle Aged, Nutrition Surveys, United States, Comorbidity, Multivariate Analysis, Confidence Intervals, Logistic Models, Young Adult, Self Report
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