Poor Control of Risk Factors for Vascular Disease Among Adults With Previously Diagnosed Diabetes

Saydah, Sharon H.

doi:10.1001/jama.291.3.335

Cited by 1,357Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Management and ResearchDiabetes Management and Education

Poor Control of Risk Factors for Vascular Disease Among Adults With Previously Diagnosed Diabetes

Saydah, Sharon H.·2004·JAMA

DOI 10.1001/jama.291.3.335

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Abstract

Context Control of blood glucose levels, blood pressure, and cholesterol levels is proven to reduce the risk of vascular disease among individuals with diabetes mellitus; however, the current state of control of these risk factors among individuals in the United States is uncertain. Objectives To examine 1999-2000 national data on control of risk factors for vascular disease among adults with previously diagnosed diabetes and to assess trends during the past decade. Design, setting, and participants Review of data from the Third National Health and Nutrition Examination Survey (NHANES III, conducted 1988-1994) and NHANES 1999-2000, cross-sectional surveys of a nationally representative sample of the noninstitutionalized civilian US population. Participants were adults aged 20 years and older with previously diagnosed diabetes who participated in both the interview and examination in either NHANES III (n = 1265) or NHANES 1999-2000 (n = 441). Main outcome measures Levels of glycosylated hemoglobin (HbA1c), blood pressure, and total serum cholesterol in reference to target goals. Results Compared with NHANES III, participants with previously diagnosed diabetes in NHANES 1999-2000 were similar by age and sex, were less likely to be non-Hispanic white, were diagnosed at an earlier age, had a higher body mass index, and were more likely to use insulin in combination with oral agents. In NHANES 1999-2000, only 37.0% of participants achieved the target goal of HbA1c level less than…

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The effect of blood-pressure reduction on cardiovascular end points usually occurs within months, whereas the effect of lipid lowering is evident after 1 to 2 years.
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Authors: Saydah, S. H.
Affiliations: Centers for Disease Control and Prevention (US)
Corresponding author: Saydah, Sharon H.
ORCID: Saydah, Sharon H.
Venue: JAMA
Publisher: American Medical Association (AMA)
Published: 2004-01-21
Volume: 291
Issue: 3
Pages: 335
ISSN: 0002-9955 (ISSN-L)
0098-7484
DOI: 10.1001/jama.291.3.335
OpenAlex: W2046645679
Cited by: 1,357
References: 5
Citations by year: 2026: 3 · 2025: 4 · 2024: 8 · 2023: 10 · 2022: 12 · 2021: 14 · 2020: 23 · 2019: 28 · 2018: 28 · 2017: 35 · 2016: 40 · 2015: 62 · 2014: 73 · 2013: 66 · 2012: 100
FWCI: 79.98
Type: journal article
Language: en
Open access: closed
Locations: JAMA (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Diabetes and Digestive and Kidney Diseases (N01-DK-1-2478)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
Keywords: diabetes mellitus, vascular risk factors, glycemic control, HbA1c, blood pressure control, hypertension, serum cholesterol, hypercholesterolemia, diabetes prevalence, insulin therapy, oral antidiabetic drugs, body mass index, cardiovascular risk, United States adults
MeSH terms: Adult, Aged, Attitude to Health, Blood Pressure, Cholesterol, Diabetes Mellitus, Diabetic Angiopathies, Female, Glycated Hemoglobin, Humans, Male, Middle Aged, Nutrition Surveys, Risk Factors, United States, Health Behavior

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Poor Control of Risk Factors for Vascular Disease Among Adults With Previously Diagnosed Diabetes

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