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Garlic: Its Anticarcinogenic and Antitumorigenic Properties
Abstract
Overall, several investigations indicate that garlic and its organic allyl sulfur components inhibit the cancer process. Furthermore, these studies reveal that the benefits of garlic are not limited to a specific species, a particular tissue, or a specific carcinogen. Finally, odor is not a prerequisite for the protection provided by garlic against the initiation of chemical carcinogenesis. Although the water-soluble compound S-allyl cysteine is effective in reducing the risk of chemically induced tumors in experimental animals, it has no effect on established tumors. However, oil-soluble compounds such as diallyl disulfide are effective in reducing the proliferation of neoplasms. Although the evidence supports the benefits of garlic, additional evidence is needed to determine the quantity needed by humans to minimize cancer risk.
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Citations
Cited by
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Song, M., Garrett, W. S., & Chan, A. T. (2015) · Gastroenterology · doi:10.1053/j.gastro.2014.12.035 · Cited by 700
Antioxidant Health Effects of Aged Garlic Extract
Borek, C. (2001) · The Journal of Nutrition · doi:10.1093/jn/131.3.1010s · Cited by 688
Ali-Shtayeh, M. S., Yaniv, Z., & Mahajna, J. (2000) · Journal of Ethnopharmacology · doi:10.1016/s0378-8741(00)00316-0 · Cited by 431
Garlic [Allium sativum]: A review of its potential use as an anti-cancer agent
Thomson, M., & Ali, M. (2003) · Current Cancer Drug Targets · doi:10.2174/1568009033333736 · Cited by 399
Growth inhibitory effects of diallyl disulfide on human breast cancer cell lines
Nakagawa, H. (2001) · Carcinogenesis · doi:10.1093/carcin/22.6.891 · Cited by 256
Metadata
- Authors
- Milner, J. A.
- Venue
- Nutrition Reviews
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-04-27
- Volume
- 54
- Issue
- 11
- Pages
- S82-S86
- ISSN
- 0029-6643 (ISSN-L)
- 1753-4887
- OpenAlex
- W1981366899
- Cited by
- 202
- References
- 0
- FWCI
- 14.74
- Type
- journal article
- Language
- en
- Open access
- closed
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- Milner, J. A. (2009). Garlic: Its Anticarcinogenic and Antitumorigenic Properties. Nutrition Reviews. https://doi.org/10.1111/j.1753-4887.1996.tb03823.x
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