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Cited by 607Diet, Metabolism, and DiseaseRegulation of Appetite and ObesityBiochemical Analysis and Sensing Techniques

The DOI matches its Crossref record; 226 of the 230 references it cites were found in a registry or an index.

Dietary fructose: implications for dysregulation of energy homeostasis and lipid/carbohydrate metabolism.

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Havel, Peter J.·2005·Nutrition Reviews
DOI 10.1111/j.1753-4887.2005.tb00132.x
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Abstract

Fructose intake and the prevalence of obesity have both increased over the past two to three decades. Compared with glucose, the hepatic metabolism of fructose favors lipogenesis, which may contribute to hyperlipidemia and obesity. Fructose does not increase insulin and leptin or suppress ghrelin, which suggests an endocrine mechanism by which it induces a positive energy balance. This review examines the available data on the effects of dietary fructose on energy homeostasis and lipid/carbohydrate metabolism. Recent publications, studies in human subjects, and areas in which additional research is needed are emphasized.

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Items 201–226 of 226

Research works printed but not linked: 8

  1. Havel, 2003, Pituitary and Periphery: Communication In and Out, 89
  2. Bowman, 1999, Diets of individuals based on energy intakes from added sugars, Fam Econ Nutr Rev, 12, 31
  3. Schwarz, 1993, De novo lipogenesis during fasting and oral fructose ingestion in lean and obese hyperinsuline-mic subjects, Diabetes, 42, A39
  4. Havel, 2003, Short-term and long-term consumption of high fructose, but not high glucose, diets increases postprandial triglyc-erides and apo-lipoprotein-B in women, J Invest Med, 51, S163
  5. Schwarz, 1993, Effect of oral fructose on lipolysis, fat oxidation, fractional and absolute de novo lipogenesis (DNL) using mass isotopomer distribution analysis (MIDA), FASEB J, 7, A867
  6. Schwarz, 1994, Effect of fructose ingestion on glucose production (GP) and de novo lipogenesis (DNL) in normal and hyperinsulinemic obese humans, Diabetes, 43, A52
  7. Moore, 2000, Fructose decreases the glucose and insulin responses to an oral glucose tolerance test (OGTT) in individuals with type 2 diabetes (DM2), Diabetes, 49, A84
  8. Havel, 2002, Consuming high fructose meals reduces 24 hour circulating insulin and leptin concentrations and does not suppress circulating ghrelin in women, J Invest Med, 50, 26A

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Metadata

Authors
Havel, P. J.
Affiliations
University of California, Davis (US)
Corresponding author
Havel, Peter J.
ORCID
Havel, Peter J.
Venue
Nutrition Reviews
Publisher
Oxford University Press (OUP)
Published
2005-05
Volume
63
Issue
5
Pages
133-157
ISSN
  • 0029-6643 (ISSN-L)
  • 1753-4887
DOI
10.1111/j.1753-4887.2005.tb00132.x
OpenAlex
W2162627097
Cited by
607
References
230
Citations by year
2026: 5 · 2025: 11 · 2024: 13 · 2023: 13 · 2022: 14 · 2021: 21 · 2020: 20 · 2019: 28 · 2018: 32 · 2017: 23 · 2016: 46 · 2015: 54 · 2014: 42 · 2013: 48 · 2012: 37
FWCI
15.31
Type
journal article
Language
en
Open access
Locations
  • Nutrition Reviews (publishedVersion)
  • PubMed (publishedVersion)
  • eScholarship (California Digital Library) (submittedVersion)
Funders
  • American Diabetes Association
  • U.S. Department of Agriculture
  • Dairy Management
  • National Institutes of Health (5r01hl075675-05, 58108, HL‐075675)
  • National Heart, Lung, and Blood Institute (HL 075675, R01 HL-091333, R01HL107256)
  • National Institute of Diabetes and Digestive and Kidney Diseases (R03DK058108, DK-58108)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
  • Health Sciences › Nursing › Nutrition and Dietetics › Biochemical Analysis and Sensing Techniques
Keywords
dietary fructose, energy homeostasis, lipid metabolism, carbohydrate metabolism, obesity, hepatic lipogenesis, hyperlipidemia, insulin, leptin, ghrelin, energy balance
MeSH terms
Beverages, Diabetes Mellitus, Type 2, Energy Metabolism, Fructose, Glucose, Humans, Hyperlipidemias, Insulin, Insulin Resistance, Obesity, Leptin, Peptide Hormones, Ghrelin

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