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Mediterranean food pattern and the primary prevention of chronic disease: recent developments
Abstract
Recent evidence supports the cardioprotective role of a Mediterranean food pattern. The major findings of the Greek and EPIC-Elderly cohort, the SUN study, the Medi-RIVAGE and the PREDIMED trials are reviewed. Definitive answers will come from ongoing primary prevention trials that assess clinical events as outcomes.
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“The efficacy of this diet results as an attenuation of inflammation and oxidative stress, and from the maintenance of a condition of eubiosis of the microbiota, involved in the general improvement of immune response in these populations (68, 83–86).”
From Immunosenescence and Its Hallmarks: How to Oppose Aging Strategically? A Review of Potential Options for Therapeutic Intervention (2019) · cites this paper as [84]
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“The reduced consumption of animal proteins, in particular red and cured meat, is also important.”
From Immunosenescence and Its Hallmarks: How to Oppose Aging Strategically? A Review of Potential Options for Therapeutic Intervention (2019) · cites this paper as [84]
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“The high rate of long living people and the low incidence of cardiovascular disease in many Mediterranean countries suggest the importance of a diet rich in fruits, vegetables, whole grains, legumes, and olive oil (probably the main anti-aging food in this area).”
From Immunosenescence and Its Hallmarks: How to Oppose Aging Strategically? A Review of Potential Options for Therapeutic Intervention (2019) · cites this paper as [84]
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“Current dietary investigations have found these fatty acids and dietary nitrate to be concentrated in the traditional Mediterranean diet, a diet with beneficial effects on the development of CVD and its risk factors[362,375–377].”
From Enterosalivary nitrate metabolism and the microbiome: Intersection of microbial metabolism, nitric oxide and diet in cardiac and pulmonary vascular health (2017) · cites this paper as [376]
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Self-citation
Metadata
- Authors
- Martinez-Gonzalez, M. A., Bes-Rastrollo, M., Serra-Majem, L., Lairon, D., Estruch, R., & Trichopoulou, A.
- Affiliations
- Inserm (FR)
- Hospital Clínic de Barcelona (ES)
- National and Kapodistrian University of Athens (GR)
- Venue
- Nutrition Reviews
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-05
- Volume
- 67
- Pages
- S111-S116
- ISSN
- 0029-6643 (ISSN-L)
- 1753-4887
- OpenAlex
- W2151919309
- Cited by
- 200
- References
- 42
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 8 · 2023: 9 · 2022: 10 · 2021: 11 · 2020: 11 · 2019: 19 · 2018: 19 · 2017: 6 · 2016: 12 · 2015: 15 · 2014: 11 · 2013: 16 · 2012: 15
- FWCI
- 14.90
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Nutrition Reviews (publishedVersion)
- PubMed (publishedVersion)
- Acceda (Universidad de Las Palmas de Gran Canaria) (submittedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Keywords
- Mediterranean diet, primary prevention, chronic disease, cardioprotection, PREDIMED trial, dietary intervention, cardiovascular disease
- MeSH terms
- Cardiovascular Diseases, Chronic Disease, Humans, Patient Compliance, Public Health, Diet, Mediterranean
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