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Cited by 294

The DOI matches its Crossref record; 120 of the 120 references it cites were found in a registry or an index.

Hydroxytyrosol: from laboratory investigations to future clinical trials

Open access
Granados-Principal, Sergio, Quiles, José L, Ramirez-Tortosa, Cesar L, Sanchez-Rovira, Pedro, Ramirez-Tortosa, M Carmen·2010·Nutrition Reviews

Abstract

Mediterranean countries have lower rates of mortality from cardiovascular disease and cancer than Northern European or other Western countries. This has been attributed, at least in part, to the so-called Mediterranean diet, which is composed of specific local foods, including olive oil. Traditionally, many beneficial properties associated with this oil have been ascribed to its high oleic acid content. Today, it is clear that many of the beneficial effects of ingesting virgin olive oil are due to its minor compounds. This review summarizes the existing knowledge concerning the chemistry, pharmacokinetics, and toxicology of hydroxytyrosol, a minor compound of virgin olive oil, as well as this compound's importance for health. The main findings in terms of its beneficial effects in cardiovascular disease and cancer, including its properties against inflammation and platelet aggregation, are emphasized. New evidence and strategies regarding the use of hydroxytyrosol as a natural drug for the prevention and treatment of diseases with high incidences in Western countries are also presented.

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Crossref · 10.1111/j.1753-4887.2010.00278.x

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Metadata

Authors
Granados-Principal, S., Quiles, J. L., Ramirez-Tortosa, C. L., Sanchez-Rovira, P., & Ramirez-Tortosa, M. C.
Venue
Nutrition Reviews
Published
2010-04
Volume
68
Issue
4
Pages
191-206
ISSN
  • 0029-6643 (ISSN-L)
  • 1753-4887
OpenAlex
W2118944124
Cited by
294
References
120
FWCI
9.63
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Hydroxytyrosol: from laboratory investigations to future clinical trials. https://app.cochat.ai/papers/10.1111/j.1753-4887.2010.00278.x
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Granados-Principal, S., Quiles, J. L., Ramirez-Tortosa, C. L., Sanchez-Rovira, P., & Ramirez-Tortosa, M. C. (2010). Hydroxytyrosol: from laboratory investigations to future clinical trials. Nutrition Reviews. https://doi.org/10.1111/j.1753-4887.2010.00278.x

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.