The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Melanocyte stem cells: a melanocyte reservoir in hair follicles for hair and skin pigmentation
Abstract
Summary: Most mammals are coated with pigmented hair. Melanocytes in each hair follicle produce melanin pigments for the hair during each hair cycle. The key to understanding the mechanism of cyclic melanin production is the melanocyte stem cell (MelSC) population, previously known as ‘amelanotic melanocytes’. The MelSCs directly adhere to hair follicle stem cells, the niche cells for MelSCs and reside in the hair follicle bulge–subbulge area, the lower permanent portion of the hair follicle, to serve as a melanocyte reservoir for skin and hair pigmentation. MelSCs form a stem cell system within individual hair follicles and provide a ‘hair pigmentary unit’ for each cycle of hair pigmentation. This review focuses on the identification of MelSCs and their characteristics and explains the importance of the MelSC population in the mechanisms of hair pigmentation, hair greying, and skin repigmentation.
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Cites
Scratching the surface of skin development
Fuchs, E. (2007) · Nature · doi:10.1038/nature05659 · Cited by 930
Mechanisms of hair graying: incomplete melanocyte stem cell maintenance in the niche
Nishimura, E. K., Granter, S. R., & Fisher, D. E. (2005) · Science · doi:10.1126/science.1099593 · Cited by 750
Self-citationAging and Genome Maintenance: Lessons from the Mouse?
Hasty, P., Campisi, J., Hoeijmakers, J., van Steeg, H., & Vijg, J. (2003) · Science · doi:10.1126/science.1079161 · Cited by 553 · cited 2×
“Why does the self-renewal of MelSCs become defective during the course of aging? Premature hair greying is commonly seen in a number of progeria syndromes, such as Werner syndrome and ataxia telangiectasia (AT) (Hasty et al., 2003; Martin, 2005) as well as after exposure to ionizing irradiation (Coolidge, 1925).”
BackgroundSlominski, A., Wortsman, J., Plonka, P. M., Schallreuter, K. U., Paus, R., & Tobin, D. J. (2005) · Journal of Investigative Dermatology · doi:10.1111/j.0022-202x.2004.23528.x · Cited by 532 · cited 2×
“Interestingly, the fates of follicular melanocytes, including their proliferation, differentiation, and death, all happen in synchronization with hair cycle progression (Nishimura et al., 2002; Slominski et al., 1994, 2005; Tobin et al., 1999).”
BackgroundAdult Stem Cells Exhibit Global Suppression of RNA Polymerase II Serine-2 Phosphorylation
Freter, R., Osawa, M., & Nishikawa, S.-I. (2010) · Stem Cells · doi:10.1002/stem.476 · Cited by 43
Cited by
The melanocyte lineage in development and disease
Mort, R. L., Jackson, I. J., & Patton, E. E. (2015) · Development · doi:10.1242/dev.106567 · Cited by 416
Liu, F., Visser, M., Duffy, D. L., Hysi, P. G., Jacobs, L. C., Lao, O., Zhong, K., Walsh, S., Chaitanya, L., Wollstein, A., et al. (2015) · Human Genetics · doi:10.1007/s00439-015-1559-0 · Cited by 172
Köhler, C., Nittner, D., Rambow, F., Radaelli, E., Stanchi, F., Vandamme, N., Baggiolini, A., Sommer, L., Berx, G., van den Oord, J. J., et al. (2017) · Cell Stem Cell · doi:10.1016/j.stem.2017.08.003 · Cited by 126
Age-induced hair greying – the multiple effects of oxidative stress
Seiberg, M. (2013) · International Journal of Cosmetic Science · doi:10.1111/ics.12090 · Cited by 94
BMP signaling: at the gate between activated melanocyte stem cells and differentiation
Infarinato, N. R., Stewart, K. S., Yang, Y., Gomez, N. C., Pasolli, H. A., Hidalgo, L., Polak, L., Carroll, T. S., & Fuchs, E. (2020) · Genes & Development · doi:10.1101/gad.340281.120 · Cited by 62
Metadata
- Authors
- Nishimura, E. K.
- Venue
- Pigment Cell & Melanoma Research
- Publisher
- Wiley
- Published
- 2011-05-05
- Volume
- 24
- Issue
- 3
- Pages
- 401-410
- ISSN
- 1755-1471 (ISSN-L)
- 1755-148X
- OpenAlex
- W1752220466
- Cited by
- 316
- References
- 5
- FWCI
- 10.21
- Type
- journal article
- Language
- en
- Open access
- closed
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- Nishimura, E. K. (2011). Melanocyte stem cells: a melanocyte reservoir in hair follicles for hair and skin pigmentation. Pigment Cell & Melanoma Research. https://doi.org/10.1111/j.1755-148x.2011.00855.x
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
