The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
Escherichia coli biofilm: development and therapeutic strategies
Abstract
Escherichia coli biofilm consists of a bacterial colony embedded in a matrix of extracellular polymeric substances (EPS) which protects the microbes from adverse environmental conditions and results in infection. Besides being the major causative agent for recurrent urinary tract infections, E. coli biofilm is also responsible for indwelling medical device-related infectivity. The cell-to-cell communication within the biofilm occurs due to quorum sensors that can modulate the key biochemical players enabling the bacteria to proliferate and intensify the resultant infections. The diversity in structural components of biofilm gets compounded due to the development of antibiotic resistance, hampering its eradication. Conventionally used antimicrobial agents have a restricted range of cellular targets and limited efficacy on biofilms. This emphasizes the need to explore the alternate therapeuticals like anti-adhesion compounds, phytochemicals, nanomaterials for effective drug delivery to restrict the growth of biofilm. The current review focuses on various aspects of E. coli biofilm development and the possible therapeutic approaches for prevention and treatment of biofilm-related infections.
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Danese, P. N., Pratt, L. A., & Kolter, R. (2000) · Journal of Bacteriology · doi:10.1128/jb.182.12.3593-3596.2000 · Cited by 653
Quorum sensing and swarming migration in bacteria
Daniels, R., Vanderleyden, J., & Michiels, J. (2004) · FEMS Microbiology Reviews · doi:10.1016/j.femsre.2003.09.004 · Cited by 622
Beloin, C., Roux, A., & Ghigo, J. M. (2008) · Current Topics in Microbiology and Immunology · doi:10.1007/978-3-540-75418-3_12 · Cited by 578
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Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation
Cegelski, L., Pinkner, J. S., Hammer, N. D., Cusumano, C. K., Hung, C. S., Chorell, E., Åberg, V., Walker, J. N., Seed, P. C., Almqvist, F., et al. (2009) · Nature Chemical Biology · doi:10.1038/nchembio.242 · Cited by 417
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Disease-induced changes in plant microbiome assembly and functional adaptation
Gao, M., Xiong, C., Gao, C., Tsui, C. K. M., Wang, M.-M., Zhou, X., Zhang, A.-M., & Cai, L. (2021) · Microbiome · doi:10.1186/s40168-021-01138-2 · Cited by 478
In situ formation of injectable hydrogels for chronic wound healing
Gao, Y., Li, Z., Huang, J., Zhao, M., & Wu, J. (2020) · Journal of Materials Chemistry B · doi:10.1039/d0tb01074j · Cited by 189
Metadata
- Authors
- Sharma, G., Sharma, S., Sharma, P., Chandola, D., Dang, S., Gupta, S., & Gabrani, R.
- Venue
- Journal of Applied Microbiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2016-03-11
- Volume
- 121
- Issue
- 2
- Pages
- 309-319
- ISSN
- 1364-5072 (ISSN-L)
- OpenAlex
- W2263985732
- Cited by
- 420
- References
- 41
- FWCI
- 6.62
- Type
- journal article
- Language
- en
- Open access
- closed
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- Sharma, G., Sharma, S., Sharma, P., Chandola, D., Dang, S., Gupta, S., & Gabrani, R. (2016). Escherichia coli biofilm: development and therapeutic strategies. Journal of Applied Microbiology. https://doi.org/10.1111/jam.13078
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
