Cited by 189Wound Healing and TreatmentsHydrogels: synthesis, properties, applicationsElectrospun Nanofibers in Biomedical Applications

In situ formation of injectable hydrogels for chronic wound healing

Gao, Yunfen, Li, Zhen, Huang, Jun, Zhao, Meng, Wu, Jun·2020·Journal of Materials Chemistry B

Abstract

Hydrogels have been widely used in wound healing treatment over the past decade. Injectable hydrogels have become a major research focus due to their unique advantages. Compared to traditional hydrogels, injectable hydrogels have good fluidity. When injected into the wound as a solution, they form a gel in situ that can fill the wound in three dimensions. This enables them to reach deep and irregular wounds that traditional hydrogels cannot fill. Injectable hydrogels greatly reduce the need for invasive surgery and are well-suited for chronic wound repair. This review article categorizes hydrogels that are commonly used in chronic wound repair according to their sources and reviews the current applications of the different types of injectable hydrogels in chronic wound repair.

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Crossref · 10.1039/d0tb01074j

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Authors
Gao, Y., Li, Z., Huang, J., Zhao, M., & Wu, J.
Affiliations
  • Sun Yat-sen University (CN)
  • Shenzhen Lansi Institute of Artificial Intelligence in Medicine
Corresponding author
Wu, Jun
Venue
Journal of Materials Chemistry B
Published
2020
Volume
8
Issue
38
Pages
8768-8780
ISSN
  • 2050-750X (ISSN-L)
  • 2050-7518
OpenAlex
W3049089141
Cited by
189
References
101
Citations by year
2026: 23 · 2025: 30 · 2024: 35 · 2023: 41 · 2022: 37 · 2021: 23
FWCI
3.10
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Materials Chemistry B (publishedVersion)
  • PubMed (publishedVersion)
  • Rare & Special e-Zone (The Hong Kong University of Science and Technology) (submittedVersion)
Funders
  • Ministry of Science and Technology of the People’s Republic of China (2018ZX10301402)
  • National Natural Science Foundation of China (51973243, 51820105004)
  • Guangdong Innovative and Entrepreneurial Research Team Program (2016ZT06S029, 2013S086)
  • Science and Technology Planning Project of Shenzhen Municipality (JCYJ20170307141438157)
  • Fundamental Research Funds for the Central Universities (191gzd35, 20ykpy15)
  • China Postdoctoral Science Foundation (2019M663246)
Topics
  • Health Sciences › Medicine › Rehabilitation › Wound Healing and Treatments
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
  • Physical Sciences › Materials Science › Biomaterials › Electrospun Nanofibers in Biomedical Applications
Keywords
injectable hydrogel, in situ gelation, chronic wound healing, wound healing
MeSH terms
Animals, Humans, Polymers, Polysaccharides, Proteins, Wound Healing, Hydrogels

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