In situ formation of injectable hydrogels for chronic wound healing
Abstract
Hydrogels have been widely used in wound healing treatment over the past decade. Injectable hydrogels have become a major research focus due to their unique advantages. Compared to traditional hydrogels, injectable hydrogels have good fluidity. When injected into the wound as a solution, they form a gel in situ that can fill the wound in three dimensions. This enables them to reach deep and irregular wounds that traditional hydrogels cannot fill. Injectable hydrogels greatly reduce the need for invasive surgery and are well-suited for chronic wound repair. This review article categorizes hydrogels that are commonly used in chronic wound repair according to their sources and reviews the current applications of the different types of injectable hydrogels in chronic wound repair.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Preformed hydrogels find it difficult to precisely fill irregular defects.
“However, since preformed hydrogels are formed in molds, they find it difficult to precisely fill irregular defects [29].”
From Mussel-Inspired Injectable Adhesive Hydrogels for Biomedical Applications (2024) · cites this paper as [29]
Cites
Chronic Wound Healing: A Review of Current Management and Treatments
Han, G., & Ceilley, R. I. (2017) · Advances in Therapy · doi:10.1007/s12325-017-0478-y · Cited by 2,105 · see citing works
Zhao, X., Wu, H., Guo, B., Dong, R., Qiu, Y., & Ma, P. X. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.01.011 · Cited by 1,982 · see citing works
Fan, Z., Liu, B., Wang, J., Zhang, S., Lin, Q., Gong, P., Ma, L., & Yang, S. (2014) · Advanced Functional Materials · doi:10.1002/adfm.201304202 · Cited by 812 · see citing works
Advances and Impact of Antioxidant Hydrogel in Chronic Wound Healing
Xu, Z., Han, S., Gu, Z., & Wu, J. (2020) · Advanced Healthcare Materials · doi:10.1002/adhm.201901502 · Cited by 720 · see citing works
Self-citationHydrogel wound dressings for bioactive treatment of acute and chronic wounds
Koehler, J., Brandl, F., & Göpferich, A. M. (2018) · European Polymer Journal · doi:10.1016/j.eurpolymj.2017.12.046 · Cited by 664 · see citing works
Enzyme-catalyzed crosslinkable hydrogels: Emerging strategies for tissue engineering
Teixeira, L. M., Feijén, J., van Blitterswijk, C., Dijkstra, P. J., & Karperien, M. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.10.067 · Cited by 617 · see citing works
Alginate hydrogels for bone tissue engineering, from injectables to bioprinting: A review
Hernández-González, A. C., Téllez-Jurado, L., & Rodríguez-Lorenzo, L. M. (2019) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2019.115514 · Cited by 552 · see citing works
Gong, C., Wu, Q., Wang, Y., Zhang, D., Luo, F., Zhao, X., Wei, Y., & Qian, Z. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.05.005 · Cited by 544 · see citing works
A mini review on hydrogels classification and recent developments in miscellaneous applications
Varaprasad, K., Raghavendra, G. M., Jayaramudu, T., Yallapu, M. M., & Sadiku, R. (2017) · Materials Science and Engineering: C · doi:10.1016/j.msec.2017.05.096 · Cited by 534 · see citing works
Studies on thermoresponsive polymers: Phase behaviour, drug delivery and biomedical applications
Gandhi, A., Paul, A., Sen, S. O., & Sen, K. K. (2015) · Asian Journal of Pharmaceutical Sciences · doi:10.1016/j.ajps.2014.08.010 · Cited by 506 · see citing works
Development of novel alginate based hydrogel films for wound healing applications
Pereira, R. F., Carvalho, A., Vaz, D. C., Gil, M. H., Mendes, A., & Bártolo, P. (2012) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2012.09.031 · Cited by 453 · see citing works
Chitosan hydrogels for sustained drug delivery
Peers, S., Montembault, A., & Ladavière, C. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.06.012 · Cited by 451 · see citing works
Escherichia coli biofilm: development and therapeutic strategies
Sharma, G., Sharma, S., Sharma, P., Chandola, D., Dang, S., Gupta, S., & Gabrani, R. (2016) · Journal of Applied Microbiology · doi:10.1111/jam.13078 · Cited by 421 · see citing works
Chitosan and Chitosan Derivatives in Drug Delivery and Tissue Engineering
Riva, R., Ragelle, H., Rieux, A. D., Duhem, N., Jérôme, C., & Véronique Préat, A. (2011) · Advances in polymer science · doi:10.1007/12_2011_137 · Cited by 367 · see citing works
Zhao, L., Niu, L., Liang, H., Tan, H., Liu, C., & Zhu, F. (2017) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b09395 · Cited by 363 · see citing works
Cheng, N., Wang, S., & Young, T. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.11.049 · Cited by 349 · see citing works
Shriky, B., Kelly, A. L., Isreb, M., Babenko, M., Mahmoudi, N., Rogers, S. E., Shebanova, O. N., Snow, T., & Gough, T. D. (2019) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2019.12.096 · Cited by 304 · see citing works
Polymers in cell encapsulation from an enveloped cell perspective
de Vos, P., Lazarjani, H. A., Poncelet, D., & Faas, M. M. (2014) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2013.11.005 · Cited by 298 · see citing works
Rezvanian, M., Ahmad, N., Amin, M. C. I. M., & Ng, S. (2017) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2016.12.079 · Cited by 297 · see citing works
Thi, P. L., Lee, Y., Tran, D. L., Thi, T. T. H., Kang, J. I., Park, K. M., & Park, K. D. (2019) · Acta Biomaterialia · doi:10.1016/j.actbio.2019.12.009 · Cited by 277 · see citing works
Matanović, M. R., Kristl, J., & Grabnar, P. A. (2014) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2014.06.029 · Cited by 249 · see citing works
Ma, M., Zhong, Y., & Jiang, X. (2020) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2020.116096 · Cited by 240 · see citing works
In situ forming hydrogels based on chitosan for drug delivery and tissue regeneration
Liu, L., Gao, Q., Lü, X., & Zhou, H. (2016) · Asian Journal of Pharmaceutical Sciences · doi:10.1016/j.ajps.2016.07.001 · Cited by 234 · see citing works
Bioactive Injectable Hydrogels Containing Desferrioxamine and Bioglass for Diabetic Wound Healing
Kong, L., Wu, Z., Zhao, H., Cui, H., Shen, J., Chang, J., Li, H., & He, Y. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b09191 · Cited by 233 · see citing works
Koutsopoulos, S. (2015) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.35638 · Cited by 232 · see citing works
Ashraf, S., Park, H., Park, H., & Lee, S. (2016) · Macromolecular Research · doi:10.1007/s13233-016-4052-2 · Cited by 223 · see citing works
Cyclodextrin-based host–guest supramolecular hydrogel and its application in biomedical fields
Liu, G., Yuan, Q., Hollett, G., Zhao, W., Kang, Y., & Wu, J. (2018) · Polymer Chemistry · doi:10.1039/c8py00730f · Cited by 210 · see citing works
Self-citationAdvances in using chitosan-based nanoparticles forin vitroandin vivodrug and gene delivery
Duceppe, N., & Tabrizian, M. (2010) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2010.514604 · Cited by 204 · see citing works
Futscher, M. H., Philipp, M., Müller‐Buschbaum, P., & Schulte, A. (2017) · Scientific Reports · doi:10.1038/s41598-017-17272-7 · Cited by 202 · see citing works
Paclitaxel-loaded pH responsive hydrogel based on self-assembled peptides for tumor targeting
Raza, F., Zhu, Y., Chen, L., You, X., Zhang, J., Asifullah, K., Khan, M. W., Hasnat, M., Zafar, H., Wu, J., et al. (2019) · Biomaterials Science · doi:10.1039/c9bm00139e · Cited by 194 · see citing works
Self-citationFibrous protein-based hydrogels for cell encapsulation
da Silva, R. S., Fabry, B., & Boccaccini, A. R. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.04.078 · Cited by 183 · see citing works
Zubik, K., Singhsa, P., Wang, Y., Manuspiya, H., & Narain, R. (2017) · Polymers · doi:10.3390/polym9040119 · Cited by 182 · see citing works
Injectable hydrogel composed of hydrophobically modified chitosan/oxidized-dextran for wound healing
Du, X., Liu, Y., Wang, X., Yan, H., Wang, L., Qu, L., Kong, D., Qiao, M., & Wang, L. (2019) · Materials Science and Engineering C · doi:10.1016/j.msec.2019.109930 · Cited by 180 · see citing works
Radhakumary, C., Antonty, M., & Sreenivasan, K. (2010) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2010.08.042 · Cited by 176 · see citing works
Liu, J. S., Li, J., Yu, F., Zhao, Y.-X., Mo, X., & Pan, J. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.01.005 · Cited by 173 · see citing works
pH-sensitive peptide hydrogel for glucose-responsive insulin delivery
Li, X., Fu, M., Wu, J., Zhang, C., Deng, X., Dhinakar, A., Huang, W., Qian, H., & Ge, L. (2017) · Acta Biomaterialia · doi:10.1016/j.actbio.2017.01.016 · Cited by 173 · see citing works
Self-citationMadry, H., Gao, L., Rey‐Rico, A., Venkatesan, J. K., Müller‐Brandt, K., Cai, X., Goebel, L. K. H., Schmitt, G., Speicher‐Mentges, S., Zurakowski, D., et al. (2019) · Advanced Materials · doi:10.1002/adma.201906508 · Cited by 167 · see citing works
Kuo, Y., Wang, C., Cheng, J., Kao, G., Chiang, Y., & Wang, C. (2016) · Cell Transplantation · doi:10.3727/096368915x687921 · Cited by 156 · see citing works
Self-Assembling Peptide Nanofibrous Hydrogel as a Versatile Drug Delivery Platform
Yu, Z., Xu, Q., Dong, C., Lee, S. S., Gao, L., Li, Y., D'Ortenzio, M., & Wu, J. (2015) · Current Pharmaceutical Design · doi:10.2174/1381612821666150901104821 · Cited by 135 · see citing works
Self-citationNatural polymers and the hydrogels prepared from them
Varghese, S. A., Rangappa, S. M., Siengchin, S., & Parameswaranpillai, J. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816421-1.00002-1 · Cited by 134 · see citing works
Cao, D., Zhang, X., Akabar, M., Luo, Y., Wu, H., Ke, X., & Ci, T. (2019) · Artificial Cells Nanomedicine and Biotechnology · doi:10.1080/21691401.2018.1548470 · Cited by 133 · see citing works
Peptidic Biomaterials: From Self-Assembling to Regenerative Medicine
Pugliese, R., & Gelain, F. (2017) · Trends in Biotechnology · doi:10.1016/j.tibtech.2016.09.004 · Cited by 133 · see citing works
Polydopamine/puerarin nanoparticle-incorporated hybrid hydrogels for enhanced wound healing
Zhang, S., Ou, Q., Xin, P., Yuan, Q., Wang, Y., & Wu, J. (2019) · Biomaterials Science · doi:10.1039/c9bm00991d · Cited by 130 · see citing works
Self-citationAtoufi, Z., Kamrava, S. K., Davachi, S. M., Hassanabadi, M., Garakani, S. S., Alizadeh, R., Farhadi, M. R., Tavakol, S., Bagher, Z., & Motlagh, G. H. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.08.101 · Cited by 129 · see citing works
Injectable baicalin/F127 hydrogel with antioxidant activity for enhanced wound healing
Liu, G., Bao, Z., & Wu, J. (2020) · Chinese Chemical Letters · doi:10.1016/j.cclet.2020.03.005 · Cited by 128 · see citing works
Self-citationDong, Y., Hassan, W. U., Kennedy, R., Greiser, U., Pandit, A. S., García, Y., & Wang, W. (2014) · Acta Biomaterialia · doi:10.1016/j.actbio.2013.12.045 · Cited by 124 · see citing works
Adipose-derived stem cells seeded in Pluronic F-127 hydrogel promotes diabetic wound healing
Kaisang, L., Wang, S., Fan, L.-J., Daoyan, P., Xian, C. J., & Shen, J. (2017) · Journal of Surgical Research · doi:10.1016/j.jss.2017.04.032 · Cited by 119 · see citing works
Multidomain Peptide Hydrogel Accelerates Healing of Full-Thickness Wounds in Diabetic Mice
Carrejo, N. C., Moore, A. N., Lopez‐Silva, T. L., Leach, D. G., Li, I.-C., Walker, D. R., & Hartgerink, J. D. (2018) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.8b00031 · Cited by 119 · see citing works
Healing of Chronic Wounds: An Update of Recent Developments and Future Possibilities
Kathawala, M. H., Ng, W. L., Liu, D., Naing, M. W., Yeong, W. Y., Spiller, K. L., Dyke, M. E. V., & Ng, K. W. (2019) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2019.0019 · Cited by 114 · see citing works
Song, Z., Chen, X., You, X., Huang, K., Dhinakar, A., Gu, Z., & Wu, J. (2017) · Biomaterials Science · doi:10.1039/c7bm00730b · Cited by 110 · see citing works
Self-citationSynthesis and super-swelling behavior of a novel protein-based superabsorbent hydrogel
Pourjavadi, A., Kurdtabar, M., Mahdavinia, G. R., & Hosseinzadeh, H. (2006) · Polymer Bulletin · doi:10.1007/s00289-006-0649-5 · Cited by 102 · see citing works
Nimal, T. R., Baranwal, G., Bavya, M. C., Biswas, R., & Jayakumar, R. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b07463 · Cited by 99 · see citing works
Gan, J., Guan, X., Zheng, J., Guo, H., Wu, K., Liang, L., & Lu, M. (2016) · RSC Advances · doi:10.1039/c6ra03045a · Cited by 97 · see citing works
Xu, H., Huang, S., Wang, J., Lan, Y., Feng, L., Zhu, M., Xiao, Y., Cheng, B., Xue, W., & Guo, R. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.06.246 · Cited by 95 · see citing works
Antibacterial PEG-Chitosan Hydrogels for Controlled Antibiotic/Protein Delivery
Sharma, P. K., Halder, M., Srivastava, U., & Singh, Y. (2019) · ACS Applied Bio Materials · doi:10.1021/acsabm.9b00570 · Cited by 95 · see citing works
In situ gel-forming AP-57 peptide delivery system for cutaneous wound healing
Li, X., Fan, R., Tong, A., Yang, M., Deng, J., Zhou, L., Zhang, X., & Guo, G. F. (2015) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2015.09.005 · Cited by 92 · see citing works
Topical drug delivery using chitosan nano- and microparticles
Sezer, A. D., & Cevher, E. (2012) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2012.702752 · Cited by 89 · see citing works
Kong, F., Fan, C., Yang, Y., Lee, B. H., & Wei, K. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.07.152 · Cited by 87 · see citing works
Talodthaisong, C., Boonta, W., Thammawithan, S., Patramanon, R., Kamonsutthipaijit, N., Hutchison, J. A., & Kulchat, S. (2020) · Materials Today Communications · doi:10.1016/j.mtcomm.2020.100992 · Cited by 80 · see citing works
Huang, J. C., Chen, L., Gu, Z., & Wu, J. (2019) · Journal of Biomedical Nanotechnology · doi:10.1166/jbn.2019.2815 · Cited by 74 · see citing works
Self-citationChan, P. S., Xian, J. W., Li, Q., Chan, C. W., Leung, S. S. Y., & To, K. K. W. (2019) · The AAPS Journal · doi:10.1208/s12248-019-0326-x · Cited by 72 · see citing works
A biomimetic self-assembling peptide promotes bone regeneration in vivo: A rat cranial defect study
Saha, S., Yang, X., Wijayathunga, N., Harris, S. A., Feichtinger, G. A., Davies, R. P., & Kirkham, J. (2019) · Bone · doi:10.1016/j.bone.2019.06.020 · Cited by 69 · see citing works
Xian, C., Gu, Z., Liu, G., & Wu, J. (2019) · Chinese Chemical Letters · doi:10.1016/j.cclet.2019.09.011 · Cited by 63 · see citing works
Self-citationSu, Y., Wang, H., Mishra, B., Narayana, J. L., Jiang, J., Reilly, D. A., Hollins, R. R., Carlson, M. A., Wang, G., & Xie, J. (2019) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.8b01345 · Cited by 61 · see citing works
Gao, N., Lü, S., Gao, C., Wang, X., Xu, X., Bai, X. F., Feng, C., & Liu, M. (2015) · Chemical Engineering Journal · doi:10.1016/j.cej.2015.11.015 · Cited by 60 · see citing works
Kim, J. E., Lee, J. H., Kim, S. H., & Jung, Y. (2017) · Tissue Engineering Part A · doi:10.1089/ten.tea.2016.0517 · Cited by 60 · see citing works
Calcium alginate-based Antimicrobial Film Dressings for Potential Healing of Infected Foot Ulcers
Ahmed, A., & Boateng, J. S. (2018) · Therapeutic Delivery · doi:10.4155/tde-2017-0104 · Cited by 59 · see citing works
Dong, Y., Zhuang, H., Hao, Y., Zhang, L., Yang, Q., Liu, Y., Qi, C., & Wang, S. (2020) · International Journal of Nanomedicine · doi:10.2147/ijn.s235609 · Cited by 58 · see citing works
Liu, D., Wu, Q., Zhu, Y., Liu, Y., Xie, X., Li, S., Lin, H., Chen, W., & Zhu, F. (2019) · Drug Delivery · doi:10.1080/10717544.2019.1609623 · Cited by 57 · see citing works
Steinman, N. Y., Zada, M. H., Goldstein, I. A., Goldberg, A. H., Haber, T., Berlin, J. M., & Domb, A. J. (2018) · Journal of Polymer Science Part A Polymer Chemistry · doi:10.1002/pola.29275 · Cited by 57 · see citing works
Xu, W.-K., Tang, J.-Y., Zhang, Y., Cai, C.-Y., Chen, X., Cui, S., Liu, P., Yu, L., Cai, K., & Ding, J. (2019) · Chinese Journal of Polymer Science · doi:10.1007/s10118-019-2212-5 · Cited by 56 · see citing works
Design of injectable hydrogels of gelatin and alginate with ferric ions for cell transplantation
Anamizu, M., & Tabata, Y. (2019) · Acta Biomaterialia · doi:10.1016/j.actbio.2019.10.001 · Cited by 54 · see citing works
Choi, H. J., Thambi, T., Yang, Y. H., Bang, S. I., Kim, B. S., Pyun, D. G., & Lee, D. S. (2017) · RSC Advances · doi:10.1039/c6ra27322j · Cited by 51 · see citing works
Injectable tissue adhesive composite hydrogel with fibroblasts for treating skin defects
Zhu, F., Wang, C., Yang, S., Wang, Q., Liang, F., Liu, C., Qiu, D., Qu, X., Hu, Z., & Yang, Z. (2017) · Journal of Materials Chemistry B · doi:10.1039/c7tb00384f · Cited by 51 · see citing works
Khorshid, N. K., Zhu, K., Knudsen, K. D., Bekhradnia, S., Sande, S. A., & Nyström, B. (2016) · Macromolecular Bioscience · doi:10.1002/mabi.201600277 · Cited by 46 · see citing works
Bellotti, E., Fedorchak, M. V., Velankar, S., & Little, S. R. (2019) · Journal of Materials Chemistry B · doi:10.1039/c8tb02976h · Cited by 46 · see citing works
PNIPAAm-MAA nanoparticles as delivery vehicles for curcumin against MCF-7 breast cancer cells
Zeighamian, V., Darabi, M., Akbarzadeh, A., Rahmati‐Yamchi, M., Zarghami, N., Badrzadeh, F., Salehi, R., Mirakabad, F. S. T., & Taheri‐Anganeh, M. (2015) · Artificial Cells Nanomedicine and Biotechnology · doi:10.3109/21691401.2014.982803 · Cited by 43 · see citing works
Thermo-sensitive hydrogel PLGA-PEG-PLGA as a vaccine delivery system for intramuscular immunization
Wang, X., Zhang, Y., Xue, W., Wang, H., Qiu, X., & Liu, Z. (2016) · Journal of Biomaterials Applications · doi:10.1177/0885328216680343 · Cited by 42 · see citing works
An Injectable Self‐Healing Hydrogel Based on Chain‐Extended PEO‐PPO‐PEO Multiblock Copolymer
Yu, H., Liu, Y., Yang, H., Peng, K., & Zhang, X. (2016) · Macromolecular Rapid Communications · doi:10.1002/marc.201600323 · Cited by 41 · see citing works
Firoozi, S., Pahlavan, S., Ghanian, M. H., Rabbani, S., Tavakol, S., Barekat, M., Yakhkeshi, S., Mahmoudi, E., Soleymani, M., & Baharvand, H. (2020) · Biomolecules · doi:10.3390/biom10020205 · Cited by 40 · see citing works
Shao, M., Hussain, Z., Thu, H. E., Khan, S., de Matas, M., Silkstone, V., Qin, H., & Bukhari, S. N. A. (2017) · Critical Reviews in Therapeutic Drug Carrier Systems · doi:10.1615/critrevtherdrugcarriersyst.2017016957 · Cited by 39 · see citing works
Dang, L. H., Huynh, N. T., Pham, N. O., Nguyen, C. T., Vu, M. T., Dinh, V. T., Lê, V. T., & Trân, N. Q. (2019) · Bulletin of Materials Science · doi:10.1007/s12034-019-1745-0 · Cited by 38 · see citing works
The Physical Chemistry for the Self-assembly of Peptide Hydrogels
Li, Y., & Cao, Y. (2017) · Chinese Journal of Polymer Science · doi:10.1007/s10118-018-2099-6 · Cited by 38 · see citing works
Fischer, M., Gebhard, F. T., Hammer, T. R., Zurek, C., Meurer, G., Marquardt, C., & Hoefer, D. (2017) · Journal of Biomaterials Applications · doi:10.1177/0885328217702173 · Cited by 37 · see citing works
Osorno, L. L., Maldonado, D. E., Whitener, R., Brandley, A., Yiantsos, A., Medina, J. D. R., & Byrne, M. E. (2019) · Journal of Applied Polymer Science · doi:10.1002/app.48678 · Cited by 36 · see citing works
Efficacy of a povidone‐iodine foam dressing (Betafoam) on diabetic foot ulcer
Gwak, H., Han, S. H., Lee, J. W., Park, S.-J., Sung, K.-S., Kim, H. J., Chun, D., Lee, K., Ahn, J., Kwak, K., et al. (2019) · International Wound Journal · doi:10.1111/iwj.13236 · Cited by 35 · see citing works
Azam, M., Dıkıcı, S., Román, S., Mehmood, A., Chaudhry, A. A., Rehman, I. U., MacNeil, S., & Yar, M. (2019) · Journal of Biomaterials Applications · doi:10.1177/0885328219859991 · Cited by 30 · see citing works
Xu, J., Feng, Y., Wu, Y., Li, Y., Ouyang, M., Zhang, X., Wang, Y., Wang, Y., & Xu, L. (2019) · Reactive and Functional Polymers · doi:10.1016/j.reactfunctpolym.2019.104333 · Cited by 30 · see citing works
Rong, X., Yang, J. P., Ji, Y., Zhu, X., Lü, Y., & Mo, X. (2018) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2018.12.032 · Cited by 29 · see citing works
Cai, J., Ye, D., Wu, Y., Fan, L. F., & Yu, H. C. (2019) · Composites Communications · doi:10.1016/j.coco.2019.06.004 · Cited by 29 · see citing works
Li, X., Chen, L., Lin, H. R., Cao, L., Cheng, J., Dong, J., Yu, L., & Ding, J. (2014) · Clinical Spine Surgery A Spine Publication · doi:10.1097/bsd.0000000000000221 · Cited by 27 · see citing works
Li, X., & Hyun, K. (2018) · Korea-Australia Rheology Journal · doi:10.1007/s13367-018-0012-z · Cited by 27 · see citing works
Chen, L., Li, X., Cao, L., Li, X., Meng, J.-R., Dong, J., Yu, L., & Ding, J. (2015) · Chinese Journal of Polymer Science · doi:10.1007/s10118-016-1740-5 · Cited by 26 · see citing works
Park, Y., Hashimoto, C., Ozaki, Y., & Jung, Y. M. (2016) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2016.02.067 · Cited by 26 · see citing works
Zanotto, G., Liebesny, P., Barrett, M. F., Zlotnick, H. M., Grodzinsky, A. J., & Frisbie, D. D. (2019) · Journal of Orthopaedic Research® · doi:10.1002/jor.24414 · Cited by 23 · see citing works
Characterization of PNIPAAm-co-AAm hydrogels for modified release of bromelain
Croisfelt, F. M., Ataide, J. A., Tundisi, L. L., Cefali, L. C., Rebelo, M. D. A., Dávila, J. L., Germano‐Costa, T., de Lima, R., Jozala, Â. F., Chaud, M. V., et al. (2018) · European Polymer Journal · doi:10.1016/j.eurpolymj.2018.05.016 · Cited by 22 · see citing works
Preparation of polysaccharide-based hydrogels via radiation technique
Li, R., & Wu, G. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816421-1.00005-7 · Cited by 21 · see citing works
Deliormanlı, A. M., & Türk, M. (2019) · Journal of Inorganic and Organometallic Polymers and Materials · doi:10.1007/s10904-019-01346-2 · Cited by 21 · see citing works
Properties and development of hydrogels
Chen, Y. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816421-1.00001-x · Cited by 18 · see citing works
Ghaouar, N., Baroudi, M., & Othman, T. (2016) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2016.09.123 · Cited by 11 · see citing works
Customizing Volume Phase Transition of Thermo‐Responsive Hydrogels
Yoon, J. (2019) · Macromolecular Symposia · doi:10.1002/masy.201800179 · Cited by 5 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Lu, P., Ruan, D., Huang, M., Tian, M., Zhu, K., Gan, Z., & Xiao, Z. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01852-x · Cited by 726 · see citing works
Qi, X., Huang, Y., You, S., Xiang, Y., Cai, E., Mao, R., Pan, W., Tong, X., Dong, W., Ye, F., et al. (2022) · Advanced Science · doi:10.1002/advs.202106015 · Cited by 519 · see citing works
Structural and biological engineering of 3D hydrogels for wound healing
Norahan, M. H., Pedroza-González, S. C., Sánchez-Salazar, M. G., Álvarez, M. M., & Santiago, G. T. (2022) · Bioactive Materials · doi:10.1016/j.bioactmat.2022.11.019 · Cited by 349 · see citing works
Multifunctional Hydrogels for the Healing of Diabetic Wounds
Xiang, T., Guo, Q., Jia, L., Yin, T., Huang, W., Zhang, X., & Zhou, S. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202301885 · Cited by 288 · see citing works
Zöller, K., To, D., & Bernkop‐Schnürch, A. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2024.122718 · Cited by 274 · see citing works
Ding, X., Li, G., Zhang, P., Jin, E., Xiao, C., & Chen, X. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202011230 · Cited by 235 · see citing works
Qi, X., Xiang, Y., Cai, E., You, S., Gao, T., Lan, Y., Deng, H., Li, Z., Hu, R., & Shen, J. (2022) · Chemical Engineering Journal · doi:10.1016/j.cej.2022.135691 · Cited by 226 · see citing works
Self-citationHydrogels and Nanogels: Pioneering the Future of Advanced Drug Delivery Systems
Delgado-Pujol, E. J., Martínez, G., Casado-Jurado, D., Vázquez, J., León-Barberena, J., Rodríguez-Lucena, D., Torres, Y., Alcudia, A., & Begines, B. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17020215 · Cited by 216 · see citing works
Collagen-based formulations for wound healing: A literature review
Sharma, S. K., Rai, V. K., Narang, R. K., & Markandeywar, T. S. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.120096 · Cited by 218 · see citing works
Hydrogel Combined with Phototherapy in Wound Healing
Xu, Y., Chen, H., Fang, Y., & Wu, J. (2022) · Advanced Healthcare Materials · doi:10.1002/adhm.202200494 · Cited by 209 · see citing works
Self-citationBiomimetic Hydrogels to Promote Wound Healing
Fan, F., Saha, S., & Hanjaya‐Putra, D. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.718377 · Cited by 193 · see citing works
Tailoring Hyaluronic Acid Hydrogels for Biomedical Applications
Luo, Z., Wang, Y., Li, J., Wang, J., Yu, Y., & Zhao, Y. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202306554 · Cited by 187 · see citing works
Recent trends on burn wound care: hydrogel dressings and scaffolds
Yao, Y., Zhang, A., Yuan, C.-S., Chen, X., & Liu, Y. (2021) · Biomaterials Science · doi:10.1039/d1bm00411e · Cited by 167 · see citing works
Wu, M., Lu, Z., Wu, K., Nam, C., Zhang, L., & Guo, J. (2021) · Journal of Materials Chemistry B · doi:10.1039/d1tb00847a · Cited by 159 · see citing works
Anti-inflammation biomaterial platforms for chronic wound healing
Xu, Z., Liang, B., Tian, J., & Wu, J. (2021) · Biomaterials Science · doi:10.1039/d1bm00637a · Cited by 151 · see citing works
Self-citationMarine Polysaccharides for Wound Dressings Application: An Overview
Shen, S., Chen, X., Shen, Z., & Chen, H. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13101666 · Cited by 150 · see citing works
Skincare application of medicinal plant polysaccharides — A review
de Albuquerque, P. B. S., de Oliveira, W. F., Silva, P. M. D. S., Correia, M. T. D. S., Kennedy, J. F., & Coelho, L. C. B. B. (2021) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2021.118824 · Cited by 142 · see citing works
Ullah, I., Zebang, C., Xie, Y., Khan, S. S., Singh, S., Yu, C., & Cheng, G. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.03.182 · Cited by 142 · see citing works
Qi, X., Pan, W., Tong, X., Gao, T., Xiang, Y., You, S., Mao, R., Chi, J., Hu, R., Zhang, W., et al. (2021) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2021.118046 · Cited by 123 · see citing works
Beneficial Effects of Green Tea EGCG on Skin Wound Healing: A Comprehensive Review
Xu, F.-W., Lv, Y.-L., Zhong, Y., Xue, Y., Wang, Y., Zhang, L., Hu, X. M., & Tan, W. (2021) · Molecules · doi:10.3390/molecules26206123 · Cited by 123 · see citing works
Electrospinning nanofibers to 1D, 2D, and 3D scaffolds and their biomedical applications
Zhong, H., Huang, J. C., Wu, J., & Du, J. (2021) · Nano Research · doi:10.1007/s12274-021-3593-7 · Cited by 112 · see citing works
Self-citationEvaluating polymeric biomaterials to improve next generation wound dressing design
Hodge, J., Zamierowski, D. S., Robinson, J. L., & Mellott, A. J. (2022) · Biomaterials Research · doi:10.1186/s40824-022-00291-5 · Cited by 113 · see citing works
Solanki, D., Vinchhi, P., & Patel, M. M. (2023) · ACS Omega · doi:10.1021/acsomega.2c06806 · Cited by 109 · see citing works
Injectable multifunctional hyaluronic acid/methylcellulose hydrogels for chronic wounds repairing
Long, L., Hu, C., Liu, W., Wu, C., Lu, L., Yang, L., & Wang, Y. (2022) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2022.119456 · Cited by 101 · see citing works
Alaoui, C. H., Réthoré, G., Weiss, P., & Fatimi, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241713493 · Cited by 100 · see citing works
Guo, Q., Yin, T., Huang, W., Nan, R., Xiang, T., & Zhou, S. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202304536 · Cited by 97 · see citing works
Advanced injectable hydrogels for cartilage tissue engineering
Zhu, S., Li, Y., He, Z., Ji, L., Zhang, W., Yu, T., Luo, J., Yu, D., Zhang, Q., & Bi, Q. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.954501 · Cited by 96 · see citing works
Zhang, K., Yang, C., Cheng, C., Shi, C., Sun, M., Hu, H., Shi, T., Chen, X., He, X., Zheng, X., et al. (2022) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c04300 · Cited by 94 · see citing works
Chen, H., Zhao, Z., Zhang, R., Zhang, G., Liang, X., Chen, X., Sun, Y., Li, Y., Boyer, C. A., & Xu, F. (2024) · Advanced Materials · doi:10.1002/adma.202413373 · Cited by 91 · see citing works
Advancements in antimicrobial nanoscale materials and self-assembling systems
Doolan, J. A., Williams, G. T., Hilton, K. L. F., Chaudhari, R., Fossey, J., Goult, B. T., & Hiscock, J. R. (2022) · Chemical Society Reviews · doi:10.1039/d1cs00915j · Cited by 90 · see citing works
Huang, D., Du, J., Luo, F., He, G., Zou, M., Wang, Y., Lin, Z., Wu, D., & Weng, Z. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202303379 · Cited by 86 · see citing works
Chitosan Hydrogel as Tissue Engineering Scaffolds for Vascular Regeneration Applications
Wang, Q., Wang, X., & Feng, Y. (2023) · Gels · doi:10.3390/gels9050373 · Cited by 85 · see citing works
Fu, C., Fan, Y., Liu, G., Li, W., Ma, J., & Xiao, J. (2023) · Chemical Engineering Journal · doi:10.1016/j.cej.2023.148288 · Cited by 85 · see citing works
An, Z., Zhang, L., Liu, Y., Zhao, H., Zhang, Y., Cao, Y., Zhang, Y., & Pei, R. (2021) · Biomaterials Science · doi:10.1039/d1bm01179k · Cited by 78 · see citing works
Shen, Q., Qi, Y., Kong, Y., Bao, H., Wang, Y., Dong, A., Wu, H., & Xu, Y. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.795425 · Cited by 76 · see citing works
Regenerative antibacterial hydrogels from medicinal molecule for diabetic wound repair
Chai, C., Zhang, P., Ma, L., Fan, Q. W., Liu, Z., Cheng, X., Zhao, Y., Li, W., & Hao, J. (2022) · Bioactive Materials · doi:10.1016/j.bioactmat.2022.07.020 · Cited by 76 · see citing works
You, S., Huang, Y., Mao, R., Xiang, Y., Cai, E., Chen, Y., Shen, J., Dong, W., & Qi, X. (2022) · Industrial Crops and Products · doi:10.1016/j.indcrop.2022.115273 · Cited by 74 · see citing works
Antibacterial Pathways in Transition Metal-Based Nanocomposites: A Mechanistic Overview
Mutalik, C., Lin, I.-H., Krisnawati, D. I., Khaerunnisa, S., Khafid, M., Widodo, W., Hsiao, Y., & Kuo, T. (2022) · International Journal of Nanomedicine · doi:10.2147/ijn.s392081 · Cited by 67 · see citing works
Engineered MXene Biomaterials for Regenerative Medicine
Zhang, S., Wang, L., Feng, Z., Wang, Z., Wang, Y., Wei, B., Liu, H., Zhao, W., & Li, J. (2025) · ACS Nano · doi:10.1021/acsnano.4c16136 · Cited by 67 · see citing works
Hyaluronic Acid‐Based Injectable Hydrogels for Wound Dressing and Localized Tumor Therapy: A Review
Xu, Y., Wang, B., Peng, D., Nie, X., Wang, J., Yu, C., & Wei, H. (2022) · Advanced NanoBiomed Research · doi:10.1002/anbr.202200124 · Cited by 66 · see citing works
Zivari‐Ghader, T., Rashidi, M., & Mehrali, M. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.134578 · Cited by 65 · see citing works
Ran, P., Zheng, H., Cao, W., Jia, X., Zhang, G., Liu, Y., & Li, X. (2022) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c15561 · Cited by 64 · see citing works
Masri, S., Mazlan, Z., Zulkiflee, I., Salleh, A., Fadilah, N. I. M., Maarof, M., Wen, A. P. Y., Duman, F., Tabata, Y., Aziz, I. A., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23010476 · Cited by 63 · see citing works
Li, Y., Song, W. D., Kong, L., He, Y., & Li, H. (2023) · Small · doi:10.1002/smll.202309599 · Cited by 54 · see citing works
Guo, Z., Yan, L., Zhou, B., Zhao, P., Wang, W., Dong, S., Cheng, B., Yang, J., Wang, X., & Li, B. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.125028 · Cited by 53 · see citing works
Mussel-Inspired Injectable Adhesive Hydrogels for Biomedical Applications
Dou, W., Zeng, X., Zhu, S., Zhu, Y., Liu, H., & Li, S. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25169100 · Cited by 52 · see citing works
Rational Design and Preparation of Functional Hydrogels for Skin Wound Healing
Hao, R., Cui, Z., Zhang, X., Tian, M., Zhang, L., Rao, F., & Xue, J. (2022) · Frontiers in Chemistry · doi:10.3389/fchem.2021.839055 · Cited by 49 · see citing works
Advances of hydrogel combined with stem cells in promoting chronic wound healing
Li, Q., Wang, D., Jiang, Z., Li, R., Xue, T., Lin, C., Deng, Y., Jin, Y. H., & Sun, B. (2022) · Frontiers in Chemistry · doi:10.3389/fchem.2022.1038839 · Cited by 49 · see citing works
Alven, S., Peter, S., & Aderibigbe, B. A. (2022) · Polymers · doi:10.3390/polym14183772 · Cited by 48 · see citing works
Hussein, M. A. M., Gündüz, O., Şahin, A., Grinholc, M., El-sherbiny, I. M., & Megahed, M. (2022) · Molecules · doi:10.3390/molecules27072146 · Cited by 48 · see citing works
Antimicrobial d -Peptide Hydrogels
Guo, Z., Wang, Y., Tan, T., Ji, Y., Hu, J., & Zhang, Y. (2021) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.1c00187 · Cited by 47 · see citing works
Huang, T., Yuan, B., Jiang, W., Ding, Y., Jiang, L., Ren, H., & Tang, J. (2021) · Journal of Materials Chemistry B · doi:10.1039/d1tb00711d · Cited by 47 · see citing works
Mao, Y., Zhang, Y., Wang, Y., Zhou, T., Ma, B., & Zhou, P. (2023) · Regenerative Biomaterials · doi:10.1093/rb/rbad046 · Cited by 46 · see citing works
Protein/polysaccharide-based hydrogels loaded probiotic-mediated therapeutic systems: A review
Zheng, B.-D., Gan, L., Tian, L.-Y., & Chen, G. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.126841 · Cited by 46 · see citing works
Babaluei, M., Mottaghitalab, F., Seifalian, A. M., & Farokhi, M. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.124005 · Cited by 45 · see citing works
RetractedChanmontri, M., Swilem, A. E., Mutch, A. L., Grøndahl, L., & Suwantong, O. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.124984 · Cited by 45 · see citing works
Yan, Z., Zhang, T., Wang, Y., Xiao, S., & Gao, J. (2023) · Materials Today Bio · doi:10.1016/j.mtbio.2023.100810 · Cited by 45 · see citing works
Engineered hydrogel platform for diabetic wound healing
Cui, J., Shi, J., Liu, Y., Shi, X., Sun, J. X., He, Z., Luo, C., & Zhang, S. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.160379 · Cited by 45 · see citing works
Genipin-Crosslinking Effects on Biomatrix Development for Cutaneous Wound Healing: A Concise Review
Utami, N. D., Fadilah, N. I. M., Sallehuddin, N., Azlan, A. Y. H. N., Imran, F.-H., Maarof, M., & Fauzi, M. B. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.865014 · Cited by 44 · see citing works
Sun, L., Zhang, Z., Cao, Y., Lu, Z., Zhang, Y., He, X., Wang, Z., & Pei, R. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.160904 · Cited by 44 · see citing works
Towards Intelligent Wound Care: Hydrogel-Based Wearable Monitoring and Therapeutic Platforms
Niu, Y., Zhao, Z., Yang, L., Lv, D., Sun, R., Zhang, T., Li, Y., Bao, Q., Zhang, M., Wang, L., et al. (2025) · Polymers · doi:10.3390/polym17131881 · Cited by 45 · see citing works
Mansouri, M., Barzi, S. M., Zafari, M., Chiani, M., Chehrazi, M., Nosrati, H., Nosrati, M. S. S., Nayyeri, S., Khodaei, M., Bonakdar, S., et al. (2022) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.35039 · Cited by 43 · see citing works
Khan, M., Shah, L. A., Yazdani, S., & Yoo, H.-M. (2023) · Sensors and Actuators A Physical · doi:10.1016/j.sna.2023.114363 · Cited by 43 · see citing works
The Role of Natural Hydrogels in Enhancing Wound Healing: From Biomaterials to Bioactive Therapies
Pintilei, P. S., Binaymotlagh, R., Chronopoulou, L., & Palocci, C. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17101243 · Cited by 43 · see citing works
Toward Designing of Anti-infective Hydrogels for Orthopedic Implants: From Lab to Clinic
Garg, D., Matai, I., & Sachdev, A. (2021) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.0c01408 · Cited by 42 · see citing works
Zong, Q., Peng, X., Ding, Y., Wu, H., Lu, C., Ye, J., Sun, W., Zhang, J., & Zhai, Y. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.125138 · Cited by 42 · see citing works
Wang, T., Ding, J., Liang, S., Lin, Z., Yang, J., Zhang, Z., Zou, Z., Li, G., Chen, X., & He, C. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202312360 · Cited by 40 · see citing works
Sustained delivery of rhMG53 promotes diabetic wound healing and hair follicle development
Niu, H. M., Li, H., Guan, Y., Zhou, X., Li, Z., Zhao, L., Chen, P., Tan, T., Hua Zhu, C., Bergdall, V. K., et al. (2022) · Bioactive Materials · doi:10.1016/j.bioactmat.2022.03.017 · Cited by 39 · see citing works
Self-citationChitosan-based immunomodulatory bioadhesive hydrogel promotes liver hemostasis and repair
Wang, W., Yao, H., Xia, J., Wan, X., & Wu, J. (2025) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2025.123268 · Cited by 42 · see citing works
Self-citationBioactive carbon dots for tissue engineering applications
Zong, Q., Chen, H., Zhao, Y., Wang, J., & Wu, J. (2023) · Smart Materials in Medicine · doi:10.1016/j.smaim.2023.06.006 · Cited by 39 · see citing works
Self-citationZheng, C., Wu, X., Liu, M., Lan, Y., Liu, Q., Cai, E., Liao, Z., & Shen, J. (2024) · Smart Medicine · doi:10.1002/smmd.20230047 · Cited by 38 · see citing works
Biopolymer hydrogels and synergistic blends for tailored wound healing
Haririan, Y., & Asefnejad, A. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.135519 · Cited by 38 · see citing works
Advances in Bioadhesive Hydrogels for Musculoskeletal Tissue Application
Zhang, F., Chien, M., Fan, Q., & Jiang, D. (2024) · Advanced Functional Materials · doi:10.1002/adfm.202316540 · Cited by 37 · see citing works
Dual-Modified Hyaluronic Acid for Tunable Double Cross-Linked Hydrogel Adhesives
Milne, C., Song, R., Johnson, M., Zhao, C., Ferrer, F. S., Sigen, A., Lyu, J., & Wang, W. (2024) · Biomacromolecules · doi:10.1021/acs.biomac.4c00194 · Cited by 34 · see citing works
Ghosh, R., Singh, P., Pandit, A. H., Tariq, U., Bhunia, B. K., & Kumar, A. (2024) · ACS Applied Bio Materials · doi:10.1021/acsabm.4c01064 · Cited by 33 · see citing works
El‐Sayed, N. S., & Kamel, S. M. (2022) · Colloids and Interfaces · doi:10.3390/colloids6040078 · Cited by 33 · see citing works
Injectable and adhesive hydrogels for dealing with wounds
Ghandforoushan, P., Golafshan, N., Kadumudi, F. B., Castilho, M. D., Dolatshahi‐Pirouz, A., & Orive, G. (2021) · Expert Opinion on Biological Therapy · doi:10.1080/14712598.2022.2008353 · Cited by 32 · see citing works
A chitosan-based antibacterial hydrogel with injectable and self-healing capabilities
Chen, R., Hao, Y., Secundo, F., Mao, X., & Huang, W. (2023) · Marine Life Science & Technology · doi:10.1007/s42995-023-00211-z · Cited by 30 · see citing works
Signaling Pathways Triggering Therapeutic Hydrogels in Promoting Chronic Wound Healing
Chen, F., Wu, P., Zhang, H., & Sun, G. (2023) · Macromolecular Bioscience · doi:10.1002/mabi.202300217 · Cited by 29 · see citing works
Yang, W., Chen, J., Zhao, Z., Wu, M. Y., Gong, L., Sun, Y., Huang, C., Yan, B., & Zeng, H. (2023) · Journal of Materials Chemistry B · doi:10.1039/d3tb02105j · Cited by 29 · see citing works
Injectable DNA Hydrogel-Based Local Drug Delivery and Immunotherapy
Wang, Q., Qu, Y., Zhang, Z., Huang, H., Xu, Y., Shen, F., Wang, L., & Sun, L. (2022) · Gels · doi:10.3390/gels8070400 · Cited by 29 · see citing works
Wu, H., Wang, T., Liang, Y., Chen, L., & Li, Z. (2023) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2023.113639 · Cited by 29 · see citing works
Self-citationRegenerative Potential of A Bovine ECM-Derived Hydrogel for Biomedical Applications
Francesco, D. D., Bertani, F., Fusaro, L., Clemente, N., Carton, F., Talmon, M., Fresu, L. G., & Boccafoschi, F. (2022) · Biomolecules · doi:10.3390/biom12091222 · Cited by 28 · see citing works
Guo, H., Shen, H., Ma, J., Wang, P., Yao, Z. Q., Zhang, W., Tan, X., & Chi, B. (2023) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.3c12027 · Cited by 26 · see citing works
Current Insight of Peptide-Based Hydrogels for Chronic Wound Healing Applications: A Concise Review
Nizam, A. A. K., Masri, S., Fadilah, N. I. M., Maarof, M., & Fauzi, M. B. (2025) · Pharmaceuticals · doi:10.3390/ph18010058 · Cited by 29 · see citing works
A Self-Supplying H2O2 Modified Nanozyme-Loaded Hydrogel for Root Canal Biofilm Eradication
Song, J., Hong, L., Zou, X., Alshawwa, H., Zhao, Y., Zhao, H., Liu, X., Si, C., & Zhang, Z. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231710107 · Cited by 25 · see citing works
Cao, L., Shao, G., Ren, F., Yang, M., Nie, Y., Peng, Q., & Zhang, P. (2021) · Drug Delivery · doi:10.1080/10717544.2020.1858998 · Cited by 24 · see citing works
RetractedRecent advances in hydrogels for preventing tumor recurrence
Qian, Q., Song, J., Chen, C., Pu, Q., Liu, X., & Wang, H. (2023) · Biomaterials Science · doi:10.1039/d3bm00003f · Cited by 24 · see citing works
Li, W., Cheng, G., Wang, S., Jiang, Y. P., Liu, X., & Huang, Q. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.129398 · Cited by 24 · see citing works
Advancements of Biomacromolecular Hydrogel Applications in Food Nutrition and Health
Ye, Z., Sun, L., Xiang, Q., Hao, Y., Liu, H., He, Q. Z., Yang, X., & Liao, W. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c05903 · Cited by 23 · see citing works
Teng, L., Shao, Z., He, Y., Lu, J., Zou, D., Feng, C., & Dong, C. (2022) · Chinese Journal of Polymer Science · doi:10.1007/s10118-022-2741-1 · Cited by 23 · see citing works
Kang, X., Lei, J., Yang, C., Zhang, P., Li, X., Zheng, S., Li, Q., & Zhang, J. (2022) · Biomaterials Science · doi:10.1039/d2bm00935h · Cited by 23 · see citing works
Chen, C., Bi, S., He, C., Liu, R., Zhao, X., Liu, J., Chen, S., Gu, J., & Yan, B. (2023) · Polymer · doi:10.1016/j.polymer.2023.126255 · Cited by 23 · see citing works
Liu, J., Deng, J., Zhao, F., Wu, T., & Xing, J. (2023) · Colloids and Surfaces A Physicochemical and Engineering Aspects · doi:10.1016/j.colsurfa.2023.133087 · Cited by 23 · see citing works
Sun, Z., Chen, X., Miao, F., Meng, N., Hu, K., Xiong, S., Peng, X., Ma, L., Zhou, C., & Yang, Y. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s474536 · Cited by 23 · see citing works
Harnessing DNA for Immunotherapy: Cancer, Infectious Diseases, and Beyond
Wang, Y., Chen‐Mayfield, T., Li, Z., Younis, M. H., Cai, W., & Hu, Q. (2022) · Advanced Functional Materials · doi:10.1002/adfm.202112273 · Cited by 22 · see citing works
Self-citationDini, C., Borges, M. H. R., Malheiros, S. S., Piazza, R. D., van den Beucken, J. J. J. P., de Ávila, É. D., Souza, J. G. S., & Barão, V. A. R. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202402926 · Cited by 21 · see citing works
Ren, M., Wang, X., Ouyang, X., Ling, J., & Wang, N. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.136514 · Cited by 21 · see citing works
Engineering Immunomodulatory Biomaterials to Drive Skin Wounds toward Regenerative HealingPreprint
Butenko, S., Miwa, H., Liu, Y., Plikus, M. V., Scumpia, P. O., & Liu, W. F. (2022) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a041242 · Cited by 20 · see citing works
Research progress of injectable hydrogels in the treatment of bone tissue diseases
Zhang, S., Li, X., Li, C., Cong, H., & Yu, B. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.155139 · Cited by 19 · see citing works
- Authors
- Gao, Y., Li, Z., Huang, J., Zhao, M., & Wu, J.
- Affiliations
- Sun Yat-sen University (CN)
- Shenzhen Lansi Institute of Artificial Intelligence in Medicine
- Corresponding author
- Wu, Jun
- Venue
- Journal of Materials Chemistry B
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2020
- Volume
- 8
- Issue
- 38
- Pages
- 8768-8780
- ISSN
- 2050-750X (ISSN-L)
- 2050-7518
- OpenAlex
- W3049089141
- Cited by
- 189
- References
- 101
- Citations by year
- 2026: 23 · 2025: 30 · 2024: 35 · 2023: 41 · 2022: 37 · 2021: 23
- FWCI
- 3.10
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Materials Chemistry B (publishedVersion)
- PubMed (publishedVersion)
- Rare & Special e-Zone (The Hong Kong University of Science and Technology) (submittedVersion)
- Funders
- Ministry of Science and Technology of the People’s Republic of China (2018ZX10301402)
- National Natural Science Foundation of China (51973243, 51820105004)
- Guangdong Innovative and Entrepreneurial Research Team Program (2016ZT06S029, 2013S086)
- Science and Technology Planning Project of Shenzhen Municipality (JCYJ20170307141438157)
- Fundamental Research Funds for the Central Universities (191gzd35, 20ykpy15)
- China Postdoctoral Science Foundation (2019M663246)
- Topics
- Health Sciences › Medicine › Rehabilitation › Wound Healing and Treatments
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
- Physical Sciences › Materials Science › Biomaterials › Electrospun Nanofibers in Biomedical Applications
- Keywords
- injectable hydrogel, in situ gelation, chronic wound healing, wound healing
- MeSH terms
- Animals, Humans, Polymers, Polysaccharides, Proteins, Wound Healing, Hydrogels
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review