The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Regenerative potential of leucocyte‐ and platelet‐rich fibrin. Part A: intra‐bony defects, furcation defects and periodontal plastic surgery. A systematic review and meta‐analysis
Open accessAbstract
Aim: To analyse the regenerative potential of leucocyte‐ and platelet‐rich fibrin (L‐PRF) during periodontal surgery. Materials and Methods: An electronic and hand search were conducted in three databases. Only randomized clinical trials were selected and no follow‐up limitation was applied. Pocket depth (PD), clinical attachment level (CAL), bone fill, keratinized tissue width (KTW), recession reduction and root coverage (%) were considered as outcome. When possible, meta‐analysis was performed. Results: Twenty‐four articles fulfilled the inclusion and exclusion criteria. Three subgroups were created: intra‐bony defects (IBD s), furcation defects and periodontal plastic surgery. Meta‐analysis was performed in all the subgroups. Significant PD reduction (1.1 ± 0.5 mm, p < 0.001), CAL gain (1.2 ± 0.6 mm, p < 0.001) and bone fill (1.7 ± 0.7 mm, p < 0.001) were found when comparing L‐PRF to open flap debridement (OFD) in IBD s. For furcation defects, significant PD reduction (1.9 ± 1.5 mm, p = 0.01), CAL gain (1.3 ± 0.4 mm, p < 0.001) and bone fill (1.5 ± 0.3 mm, p < 0.001) were reported when comparing L‐PRF to OFD. When L‐PRF was compared to a connective tissue graft, similar outcomes were recorded for PD reduction (0.2 ± 0.3 mm, p > 0.05), CAL gain (0.2 ± 0.5 mm, p > 0.05), KTW (0.3 ± 0.4 mm, p > 0.05) and recession reduction (0.2 ± 0.3 mm, p > 0.05). Conclusions: L‐PRF enhances periodontal wound healing.
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Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & The PRISMA Group (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000097 · Cited by 64,042
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859
Danaei, G., Ding, E. L., Mozaffarian, D., Taylor, B., Rehm, J., Murray, C. J. L., & Ezzati, M. (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000058 · Cited by 2,860
Marx, R. E., Carlson, E. R., Eichstaedt, R. M., Schimmele, S. R., Strauss, J. E., & Georgeff, K. R. (1998) · Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology · doi:10.1016/s1079-2104(98)90029-4 · Cited by 2,598
Dohan, D. M., Choukroun, J., Diss, A., Dohan, S. L., Dohan, A. J. J., Mouhyi, J., & Gogly, B. (2006) · Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology · doi:10.1016/j.tripleo.2005.07.008 · Cited by 1,861
Platelet-Rich Plasma (PRP): What Is PRP and What Is Not PRP?
Marx, R. E. (2001) · Implant Dentistry · doi:10.1097/00008505-200110000-00002 · Cited by 1,704
Dohan, D. M., Choukroun, J., Diss, A., Dohan, S. L., Dohan, A. J. J., Mouhyi, J., & Gogly, B. (2006) · Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology · doi:10.1016/j.tripleo.2005.07.009 · Cited by 1,191
Dohan, D. M., Choukroun, J., Diss, A., Dohan, S. L., Dohan, A. J. J., Mouhyi, J., & Gogly, B. (2006) · Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology · doi:10.1016/j.tripleo.2005.07.010 · Cited by 713
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Cited by
Serum C-Reactive Protein and Periodontitis: A Systematic Review and Meta-Analysis
Machado, V., Botelho, J., Escalda, C., Hussain, S. B., Luthra, S., Mascarenhas, P., Orlandi, M., Mendes, J. J., & D’Aiuto, F. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.706432 · Cited by 160
Metadata
- Authors
- Castro, A. B., Meschi, N., Temmerman, A., Pinto, N., Lambrechts, P., Teughels, W., & Quirynen, M.
- Venue
- Journal of Clinical Periodontology
- Publisher
- Wiley
- Published
- 2016-11-24
- Volume
- 44
- Issue
- 1
- Pages
- 67-82
- ISSN
- 0303-6979 (ISSN-L)
- 1600-051X
- OpenAlex
- W2543304149
- Cited by
- 258
- References
- 29
- FWCI
- 5.29
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Castro, A. B., Meschi, N., Temmerman, A., Pinto, N., Lambrechts, P., Teughels, W., & Quirynen, M. (2017). Regenerative potential of leucocyte‐ and platelet‐rich fibrin. Part A: intra‐bony defects, furcation defects and periodontal plastic surgery. A systematic review and meta‐analysis. Journal of Clinical Periodontology. https://doi.org/10.1111/jcpe.12643
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