The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Three‐Dimensional Architecture and Cell Composition of a Choukroun's Platelet‐Rich Fibrin Clot and Membrane
Abstract
Background: Platelet‐rich fibrin (PRF; Choukroun's technique) is a second‐generation platelet concentrate for surgical use. This easy protocol allows the production of leukocyte‐ and platelet‐rich fibrin clots and membranes starting from 10‐ml blood samples. The purposes of this study were to determine the cell composition and three‐dimensional organization of this autologous biomaterial and to evaluate the influence of different collection tubes (dry glass or glass‐coated plastic tubes) and compression procedures (forcible or soft) on the final PRF‐membrane architecture. Methods: After centrifugation, blood analyses were performed on the residual waste plasmatic layers after collecting PRF clots. The PRF clots and membranes were processed for examination by light microscopy and scanning electron microscopy. Results: Approximately 97% of the platelets and >50% of the leukocytes were concentrated in the PRF clot and showed a specific three‐dimensional distribution, depending on the centrifugation forces. Platelets and fibrin formed large clusters of coagulation in the first millimeters of the membrane beyond the red blood cell base. The fibrin network was very mature and dense. Moreover, there was no significant difference in the PRF architecture between groups using the different tested collection tubes and compression techniques, even if these two parameters could have influenced the growth factor content and biologic matrix properties. Conclusions: The PRF protocol concentrated most platelets and leukocytes from a blood harvest into a single autologous fibrin biomaterial. This protocol offers reproducible results as long as the main production principles are respected.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Marx, R. E., Carlson, E. R., Eichstaedt, R. M., Schimmele, S. R., Strauss, J. E., & Georgeff, K. R. (1998) · Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology · doi:10.1016/s1079-2104(98)90029-4 · Cited by 2,598
Dohan Ehrenfest, D. M., Rasmusson, L., & Albrektsson, T. (2009) · Trends in Biotechnology · doi:10.1016/j.tibtech.2008.11.009 · Cited by 2,008
Self-citationDohan, D. M., Choukroun, J., Diss, A., Dohan, S. L., Dohan, A. J. J., Mouhyi, J., & Gogly, B. (2006) · Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology · doi:10.1016/j.tripleo.2005.07.008 · Cited by 1,861
Self-citationChoukroun, J., Diss, A., Simonpieri, A., Girard, M.-O., Schoeffler, C., Dohan, S. L., Dohan, A. J. J., Mouhyi, J., & Dohan, D. (2006) · Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology · doi:10.1016/j.tripleo.2005.07.011 · Cited by 1,328
Self-citationDohan, D. M., Choukroun, J., Diss, A., Dohan, S. L., Dohan, A. J. J., Mouhyi, J., & Gogly, B. (2006) · Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology · doi:10.1016/j.tripleo.2005.07.009 · Cited by 1,191
Self-citationChoukroun, J., Diss, A., Simonpieri, A., Girard, M.-O., Schoeffler, C., Dohan, S. L., Dohan, A. J. J., Mouhyi, J., & Dohan, D. M. (2006) · Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology · doi:10.1016/j.tripleo.2005.07.012 · Cited by 734
Self-citationDohan, D. M., Choukroun, J., Diss, A., Dohan, S. L., Dohan, A. J. J., Mouhyi, J., & Gogly, B. (2006) · Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology · doi:10.1016/j.tripleo.2005.07.010 · Cited by 713
Self-citationThe Structure and Biological Features of Fibrinogen and Fibrin
MOSESSON, M. W., SIEBENLIST, K. R., & MEH, D. A. (2001) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2001.tb03491.x · Cited by 627
Dohan Ehrenfest, D. M., de Peppo, G. M., Doglioli, P., & Sammartino, G. (2009) · Growth Factors · doi:10.1080/08977190802636713 · Cited by 593
Self-citationCLARK, R. A. F. (2001) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2001.tb03522.x · Cited by 507
Cited by
Micko, L., Salma, I., Skadins, I., Egle, K., Salms, G., & Dubnika, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24021073 · Cited by 12
Metadata
- Authors
- Dohan Ehrenfest, D. M., Del Corso, M., Diss, A., Mouhyi, J., & Charrier, J.
- Venue
- Journal of Periodontology
- Publisher
- Wiley
- Published
- 2010-04
- Volume
- 81
- Issue
- 4
- Pages
- 546-555
- ISSN
- 0022-3492 (ISSN-L)
- 1943-3670
- OpenAlex
- W2125064090
- Cited by
- 587
- References
- 18
- FWCI
- 21.94
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Three‐Dimensional Architecture and Cell Composition of a Choukroun's Platelet‐Rich Fibrin Clot and Membrane. https://app.cochat.ai/papers/10.1902/jop.2009.090531
- The paper
- Dohan Ehrenfest, D. M., Del Corso, M., Diss, A., Mouhyi, J., & Charrier, J. (2010). Three‐Dimensional Architecture and Cell Composition of a Choukroun's Platelet‐Rich Fibrin Clot and Membrane. Journal of Periodontology. https://doi.org/10.1902/jop.2009.090531
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
