Editorial Perspective: Longitudinal research in autism – introducing the concept of ‘chronogeneity’
Open accessAbstract
Autism Spectrum Disorder ( ASD or autism) is a heterogeneous neurodevelopmental disorder. We are now at a critical juncture in autism research where we have the knowledge base and expertise to begin to think about studies that view heterogeneity, not as ‘statistical noise’ that can be ‘accounted for’ using data‐reduction techniques (such as group trajectories), but rather as ‘informative variance’ that can help form a more precise and dynamic picture of autism. In this Editorial we coin a new term and introduce the concept of ‘chronogeneity’ for the study of autism heterogeneity in relation to the dimension of time (chrono). Using examples of ongoing research and analytical advances we build the case for the potential utility of the concept of ‘chronogeneity’ and argue that a refined approach to the longitudinal investigation of autism (and other neurodevelopmental disorders) may move us closer to more precise and adaptive models of care for the children and youth affected by these disorders.
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Some individuals diagnosed as children have no clinically meaningful (or even detectable) impairment later in life (so-called 'optimal outcome').
“Some individuals diagnosed as children have no clinically meaningful (or even detectable) impairment later in life (socalled 'optimal outcome' 141,142 )”
From Autism spectrum disorder (2020) · cites this paper as [141]
The editorial discusses differing developmental trajectories in children diagnosed with autism, but does not say that some have no clinically meaningful or detectable impairment later in life. Searches for “optimal outcome” and for loss of diagnostic-level impairment did not locate that claim in our copy; no page numbers were supplied for the passages. (LLM, conf=0.73)
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Self-citation
- Authors
- Georgiades, S., Bishop, S. L., & Frazier, T.
- Affiliations
- McMaster University (CA)
- University of California, San Francisco (US)
- Cleveland Clinic (US)
- Corresponding author
- Georgiades, Stelios
- Venue
- Journal of Child Psychology and Psychiatry
- Publisher
- Wiley
- Published
- 2017-04-17
- Volume
- 58
- Issue
- 5
- Pages
- 634-636
- ISSN
- 0021-9630 (ISSN-L)
- 1469-7610
- OpenAlex
- W2605441208
- Cited by
- 100
- References
- 11
- Citations by year
- 2026: 4 · 2025: 10 · 2024: 9 · 2023: 27 · 2022: 6 · 2021: 12 · 2020: 17 · 2019: 4 · 2018: 8 · 2017: 2 · 2013: 1
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Child Psychology and Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Hamilton Health Sciences
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Keywords
- autism spectrum disorder, autism heterogeneity, longitudinal study, neurodevelopmental disorders, developmental trajectories, models of care, children and young people
- MeSH terms
- Autism Spectrum Disorder, Humans, Time Factors, Disease Progression
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