Optimization of Antioxidant Compounds Extraction from Fruit By-Products: Apple Pomace, Orange and Banana Peel: Optimization of Bioactive Compounds from By-Product
Open accessAbstract
The aim of this research was to optimize, by response surface methodology, antioxidant compounds extraction from apple pomace, orange and banana peel. The extracts were obtained at different temperatures and times. All by-products show a good content of vitamin C (12–102 mg of ascorbic acid/100 g dw), flavonoids (455–756 mg of catechin/100 g dw), phenolic compounds (227–689 mg of gallic acid equivalent/100 g dw), antioxidant capacity by 2,2-diphenyl-1-picrylhydrazyl (DPPH; 454–1,040 mg of Trolox/100 g dw) and ferric-reducing antioxidant power (FRAP; 4–32 mM Fe2+/100 g dw) assays. Polynomial models obtained from each by-product showed a good fitting (0.81–0.97). Temperatures of 41–60C promote the major extraction of bioactive compounds and antioxidant capacity from apple pomace. In orange peel, the optimum condition for vitamin C extraction was 20C (0.5 h); flavonoids, total phenols and antioxidant capacity (DPPH) were mostly extracted at 60C. In banana peel, the optimization indicates that major flavonoid concentration and antioxidant capacity (DPPH and FRAP assays) were at 60C (0.5 h). Practical Applications By-products are a good source of bioactive compounds that could be used to obtain products with added value; in this sense, the optimization of extraction of bioactive compounds with antioxidant capacity may be an important step in order to obtain the major concentration of antioxidant compounds with the less use of energy and cost. Therefore, the information presented in this study may be a good tool to apply in the industrial extraction of bioactive compounds from apple pomace, orange and banana peel.
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Banana peels contain 5-47 mg gallic acid equivalent/g dry matter (mg GAE/g DM) phenolics, which is 1.5-3 times more than in the flesh.
“Banana peels contain 5-47 mg gallic acid equivalent/g dry matter (mg GAE/g DM) phenolics [98,99], which is 1.5-3 times more than in the flesh [100].”
From Potential Valorization of Banana Production Waste in Developing Countries: Bio-Engineering Aspects (2024) · cites this paper as [99]
The Optimization of Bioactive Compound Extraction from By-Products section reports banana-peel phenolics of 304–500 mg GAE/100 g dry weight, or 3.04–5 mg GAE/g. It supports the presence of phenolics but not the attributed 5–47 mg GAE/g range. The peel-versus-flesh ratio is attached to a different citation [100], so it is not assessed against this source. (LLM, conf=0.86)
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Cites
Balasundram, N., Sundram, K., & Samman, S. (2005) · Food Chemistry · doi:10.1016/j.foodchem.2005.07.042 · Cited by 3,128 · see citing works
Preharvest and postharvest factors influencing vitamin C content of horticultural crops
Lee, S. K., & Kader, A. A. (2000) · Postharvest Biology and Technology · doi:10.1016/s0925-5214(00)00133-2 · Cited by 2,458 · see citing works
Biochemistry of Fruit Ripening
Seymour, G. B., Taylor, J. E., & Tucker, G. A. (1993) · Springer eBooks · doi:10.1007/978-94-011-1584-1 · Cited by 1,220 · see citing works
Uses and Properties ofCitrusFlavonoids
Benavente-García, O., Castillo, J., Marín, F. R., Ortuño, A. M., & del Rı́o, J. A. (1997) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf970373s · Cited by 867 · see citing works
Antioxidant activities of peel, pulp and seed fractions of common fruits as determined by FRAP assay
Guo, C., Yang, J., Wei, J., Li, Y., Xu, J., & Jiang, Y. (2003) · Nutrition Research · doi:10.1016/j.nutres.2003.08.005 · Cited by 825 · see citing works
Khan, M. K., Vian, M. A., Fabiano‐Tixier, A., Dangles, O., & Chemat, F. (2009) · Food Chemistry · doi:10.1016/j.foodchem.2009.08.046 · Cited by 726 · see citing works
Gao, X., Ohlander, M., Jeppsson, N., Björk, L., & Trajkovski, V. (2000) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf991072g · Cited by 691 · see citing works
Antioxidant and radical scavenging activities of polyphenols from apple pomace
Lu, Y., & Foo, L. Y. (2000) · Food Chemistry · doi:10.1016/s0308-8146(99)00167-3 · Cited by 675 · see citing works
Antioxidant Activity and Phenolic Composition of Citrus Peel and Seed Extracts
Bocco, A., Cuvelier, M., Richard, H. M. J., & Berset, C. (1998) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf9709562 · Cited by 673 · see citing works
Major Phenolics in Apple and Their Contribution to the Total Antioxidant Capacity
Lee, K. W., Kim, Y. J., Kim, D., Lee, H. J., & Lee, C. Y. (2003) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf034475w · Cited by 611 · see citing works
Effect of Heat Treatment on the Antioxidant Activity of Extracts from Citrus Peels
Jeong, S., Kim, S., Kim, D.-R., Jo, S., Nam, K., Ahn, D. U., & Lee, S. (2004) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf049899k · Cited by 573 · see citing works
Antioxidant activity, phenol and flavonoid contents of 13 citrus species peels and tissues.
Ghasemi, K., Ghasemi, Y., & Ebrahimzadeh, M. A. (2009) · PubMed · Cited by 562 · see citing works
Antioxidant compounds from bananas (Musa Cavendish)
Someya, S., Yoshiki, Y., & Okubo, K. (2002) · Food Chemistry · doi:10.1016/s0308-8146(02)00186-3 · Cited by 492 · see citing works
Radical scavenging activity of various extracts and fractions of sweet orange peel (Citrus sinensis)
Anagnostopoulou, M. A., Kefalas, P., Papageorgiou, V. P., Assimopoulou, A. N., & Boskou, D. G. (2004) · Food Chemistry · doi:10.1016/j.foodchem.2004.09.047 · Cited by 481 · see citing works
González-Montelongo, R., Gloria Lobo, M., & González, M. (2010) · Food Chemistry · doi:10.1016/j.foodchem.2009.08.012 · Cited by 429 · see citing works
High content of dopamine, a strong antioxidant, in cavendish banana
Kanazawa, K., & Sakakibara, H. (2000) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf9909860 · Cited by 406 · see citing works
Escarpa, A., & González, M. C. (1998) · Journal of Chromatography A · doi:10.1016/s0021-9673(98)00294-5 · Cited by 352 · see citing works
Sulaiman, S. F., Yusoff, N. A. M., Eldeen, I. M., Seow, E. M., Sajak, A. A. B., Supriatno, & Ooi, K. L. (2011) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2010.04.005 · Cited by 323 · see citing works
Nagy, S., Shaw, P. E., & Veldhuis, M. K. (1977) · Cited by 317 · see citing works
Chinnici, F., Bendini, A., Gaiani, A., & Riponi, C. (2004) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf049770a · Cited by 315 · see citing works
Pompeu, D. R., da Silva, E. M., & Rogez, H. L. G. (2009) · Bioresource Technology · doi:10.1016/j.biortech.2009.03.083 · Cited by 287 · see citing works
In vitro evaluation of the antioxidant activities in fruit extracts from citron and blood orange
Jayaprakasha, G. K., & Patil, B. S. (2006) · Food Chemistry · doi:10.1016/j.foodchem.2005.12.038 · Cited by 268 · see citing works
Londoño‐Londoño, J., de Lima, V. R., Lara-Guzmán, O. J., Gil, A., Creczynski‐Pasa, T. B., Arango, G. J. M., & Ramírez‐Pineda, J. R. (2009) · Food Chemistry · doi:10.1016/j.foodchem.2009.05.075 · Cited by 228 · see citing works
Effect of Processing on the Flavonoid Content in Buckwheat (Fagopyrum esculentum Möench) Grain
Dietrych-Szóstak, D., & Oleszek, W. A. (1999) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf990121m · Cited by 223 · see citing works
Ultrasound-assisted extraction of hesperidin from Penggan (Citrus reticulata) peel
Ma, Y., Ye, X., Hao, Y., Xu, G., Xu, G., & Liu, D. (2007) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2007.03.006 · Cited by 209 · see citing works
Gan, C., & Latiff, A. A. (2010) · Food Chemistry · doi:10.1016/j.foodchem.2010.07.074 · Cited by 204 · see citing works
Veberič, R., Trobec, M., Herbinger, K., Hofer, M., Grill, D., & Štampar, F. (2005) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.2113 · Cited by 197 · see citing works
Henríquez, C., Almonacid, S., Italo Chiffelle, G., Valenzuela, T., Araya, M. A., Cabezas, L., Simpson, R. J., & Speisky, H. (2010) · Chilean journal of agricultural research · doi:10.4067/s0718-58392010000400001 · Cited by 140 · see citing works
The Optimization of Extraction of Antioxidants from Apple Pomace by Pressurized Liquids
Wijngaard, H. H., & Brunton, N. P. (2009) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf902498y · Cited by 128 · see citing works
Distribution and potential of bioenergy resources from agricultural activities in Mexico
Vazquez, I. V., Acevedo-Benítez, J. A., & Hernández-Santiago, C. (2010) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2010.03.034 · Cited by 126 · see citing works
Supercritical fluid extraction of naringin from the peel of Citrus paradisi
Giannuzzo, A. N., Boggetti, H. J., Nazareno, M. A., & Mishima, H. T. (2003) · Phytochemical Analysis · doi:10.1002/pca.706 · Cited by 120 · see citing works
Antioxidant Activities of Orange Peel Extracts
Hegazy, A. Z., & Ibrahium, M. I. (2012) · Cited by 115 · see citing works
Antioxidant activity of banana flavonoids
Vijayakumar, S., Presannakumar, G., & Vijayalakshmi, N. R. (2008) · Fitoterapia · doi:10.1016/j.fitote.2008.01.007 · Cited by 83 · see citing works
Tsai, H.-L., Chang, S. K. C., & Chang, S.-J. (2007) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0633847 · Cited by 82 · see citing works
Braddock, R. J. (1995) · Food technology · Cited by 78 · see citing works
Postharvest quality of peeled prickly pear fruit treated with acetic acid and chitosan
Ochoa‐Velasco, C. E., & Guerrero-Beltrán, J. Á. (2014) · Postharvest Biology and Technology · doi:10.1016/j.postharvbio.2014.01.023 · Cited by 72 · see citing works
Self-citationZeković, Z., Jokić, S., Vidović, S., Lepojević, Ž., Milošević, S., & Radojković, M. (2012) · University of Zagreb University Computing Centre (SRCE) · Cited by 62 · see citing works
Julián-Loaeza, A. P., Santos-Sánchez, N. F., Valadez-Blanco, R., et al. (2010) · Industrial Crops and Products · doi:10.1016/j.indcrop.2010.06.012 · Cited by 50 · see citing works
Kong, K. W., Ismail, A. R., Tan, S. T., Prasad, K. N., & Ismail, A. (2010) · International Journal of Food Science & Technology · doi:10.1111/j.1365-2621.2010.02335.x · Cited by 36 · see citing works
Luna-Guevara, M. L., Jiménez-González, O., Guevara, J. J. L., et al. (2014) · Journal of Food Research · doi:10.5539/jfr.v3n5p8 · Cited by 17 · see citing works
Comparative analysis of vitamin C content and antioxidant activity of some fruits extracts
Dumbravă, D.-G. (2012) · Cited by 11 · see citing works
[Orange juice residues as dietary fiber source for foods].
Sáenz, C., Estévez, A., & Sanhueza, S. (2007) · PubMed · Cited by 8 · see citing works
Flagged first, then by citations
Research works printed but not linked: 2
- OCHOA-VELASCO, C.E., VALADEZ-BLANCO, R., SALAS-CORONADO, R., SUSTAITA-RIVERA, F., HERNÁNDEZ-CARLOS, B., GARCÍA-ORTEGA, S. and SANTOS-SÁNCHEZ, N.F. 2014. Evaluation of nitrogen content and plant grown promotion rhizobacteria in the bioactive compounds and antioxidant activity of tomatoes (Solanum lycopersicum L.) cultivated in greenhouse. Proceedings 6° Food Science Biotechnology Safety, October 8-10, Monterrey NL, Mexico.
- SEYMOUR, G.B. 1993. Biochemistry in Fruit Ripening, pp. 95-98, Chapman and Hall, London.
Cited by
Sorted by citations
Phenolic compounds within banana peel and their potential uses: A review
Vu, H. T., Scarlett, C. J., & Vuong, Q. V. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2017.11.006 · Cited by 381 · see citing works
Banana peels as a bioactive ingredient and its potential application in the food industry
Mohd Zaini, H., Roslan, J., Saallah, S., Munsu, E., Sulaiman, N. S., & Pindi, W. (2022) · Journal of Functional Foods · doi:10.1016/j.jff.2022.105054 · Cited by 259 · see citing works
Trigo, J. P., Alexandre, E. M. C., Saraiva, J. A., & Pintado, M. E. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2019.1572588 · Cited by 247 · see citing works
Abdeltaif, S. A., SirElkhatim, K. A., & Hassan, A. B. (2018) · Recycling · doi:10.3390/recycling3020027 · Cited by 95 · see citing works
da Silva, L. C., Viganó, J., de Souza Mesquita, L. M., Dias, A. L. B., de Souza, M. C., Sanches, V. L., Chaves, J. O., Pizani, R. S., Contieri, L. S., & Rostagno, M. A. (2021) · Food Chemistry: X · doi:10.1016/j.fochx.2021.100133 · Cited by 78 · see citing works
Bioactive, antioxidant, industrial, and nutraceutical applications of banana peel
Bhavani, M., Morya, S., Saxena, D., & Awuchi, C. G. (2023) · International Journal of Food Properties · doi:10.1080/10942912.2023.2209701 · Cited by 57 · see citing works
“[ 67 ] ( C o n t i n u e d ) M i c r o w a v e - a ss i s t e d e x t r a c t i o n m e t h o d r e s u l t s w e r e g oo d , a s i t s h o w s c l o s e v a l u e b e t w ee n p r e d i c t e d ( 12 .”
Putra, N. R., Aziz, A. H. A., Faizal, A. N. M., & Che Yunus, M. A. (2022) · Sustainability · doi:10.3390/su141710571 · Cited by 52 · see citing works
Eixenberger, D., Carballo-Arce, A.-F., Vega-Baudrit, J.-R., Trimino-Vazquez, H., Villegas-Peñaranda, L. R., Stöbener, A., Aguilar, F., Mora-Villalobos, J.-A., Sandoval-Barrantes, M., Bubenheim, P., et al. (2024) · Biomass Conversion and Biorefinery · doi:10.1007/s13399-022-02721-9 · Cited by 51 · see citing works
Wani, K. M., & Dhanya, M. (2025) · Discover Food · doi:10.1007/s44187-025-00276-y · Cited by 51 · see citing works
“Currently, a range of solvent-based extraction methods is employed for this purpose, with hot water bath extraction and Soxhlet extraction being among the most widely used techniques [9].”
InfluentialPasha, I., Basit, A., Ahsin, M., & Ahmad, F. (2022) · Food Production, Processing and Nutrition · doi:10.1186/s43014-022-00100-5 · Cited by 16 · see citing works
Potential Valorization of Banana Production Waste in Developing Countries: Bio-Engineering Aspects
Waraczewski, R., & Sołowiej, B. G. (2024) · Fibers · doi:10.3390/fib12090072 · Cited by 10 · see citing works
Extraction and formulation of valuable components from banana peels
Davy, P., Vu, H. T., & Vuong, Q. V. (2024) · Banana Peels Valorization · doi:10.1016/b978-0-323-95937-7.00003-2 · Cited by 2 · see citing works
- Authors
- Hernández-Carranza, P., Ávila-Sosa, R., Guerrero-Beltrán, J. A., Navarro-Cruz, A. R., Corona-Jiménez, E., & Ochoa-Velasco, C. E.
- Affiliations
- Ingeniería en Alimentos, Facultad de Ingeniería Química, Benemérita Universidad Autónoma de Puebla, 14 Sur y Av. San Claudio; Ciudad Universitaria; Col. San Manuel 72420 Puebla Puebla México
- Benemérita Universidad Autónoma de Puebla (MX)
- Departamento de Ingeniería Química, Alimentos y Ambiental; Universidad de las Américas Puebla; Calle Ex Hacienda s/n; Santa Catarina Mártir; Cholula Puebla 72810 México
- Departamento de Bioquímica-Alimentos, Facultad de Ciencias Químicas; Benemérita Universidad Autónoma de Puebla; 14 Sur y Av. San Claudio, Ciudad Universitaria, Col. San Manuel Puebla Puebla 72420 México
- Venue
- Journal of Food Processing and Preservation
- Publisher
- Hindawi Limited
- Published
- 2015-10-07
- Volume
- 40
- Issue
- 1
- Pages
- 103-115
- ISSN
- 0145-8892 (ISSN-L)
- OpenAlex
- W1911930177
- Cited by
- 142
- References
- 42
- Citations by year
- 2026: 10 · 2025: 17 · 2024: 17 · 2023: 18 · 2022: 29 · 2021: 13 · 2020: 13 · 2019: 9 · 2018: 6 · 2017: 9 · 2016: 1
- FWCI
- 3.66
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Food Processing and Preservation (publishedVersion)
- Topics
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural and Biological Research
- Life Sciences › Agricultural and Biological Sciences › Food Science › Food and Agricultural Sciences
- Keywords
- fruit by-products, apple pomace, orange peel, banana peel, antioxidants, extraction optimization, extraction temperature, extraction time, vitamin C, flavonoids, phenolic compounds, DPPH radical scavenging, FRAP, bioactive compounds
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