Effects of Multicomponent Exercise on Frailty in Long-Term Nursing Homes: A Randomized Controlled Trial
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OBJECTIVES: To determine the effect of multicomponent exercise on frailty and related adverse outcomes in residents of long‐term nursing homes (LTNHs). DESIGN: A single‐blind randomized controlled trial. SETTING: Ten LTNHs in Gipuzkoa, Spain. PARTICIPANTS: The study sample comprised 112 men and women aged 70 years or older who scored 50 or higher on the Barthel Index, 20 or higher on the MEC‐35 test (an adapted and validated version of the Mini‐Mental State Examination in Spanish), and who were capable of standing up and walking independently for at least 10 m. INTERVENTION: Subjects in the control group (CG) participated in routine activities. The intervention group (IG) participated in a 6‐month program of individualized and progressive multicomponent exercise at moderate intensity. MEASUREMENTS: Frailty was assessed by four different scales at baseline and at 6 months. The Barthel Index was measured at baseline and at 12 months. Frailty‐related adverse outcomes were recorded from 12 months before to 12 months after starting the intervention. RESULTS: A lower prevalence of frailty was observed in the IG compared with the CG according to Fried's frailty phenotype, Short Physical Performance Battery, and Tilburg Frailty Indicator after 6 months ( p < .05). There was a decline in the CG on the Barthel Index after 12 months ( p < .05), whereas score was maintained in the IG. Both groups experienced a similar number of falls before and after the intervention ( p > .05), but during the 6‐month intervention period, fewer falls were observed in the IG than the CG ( p < .05). Lower overall mortality was observed 12 months after starting the intervention for the IG than the CG (1 vs 6, respectively; p = .05). CONCLUSION: Individualized and progressive multicomponent exercise at moderate intensity seems to be effective to prevent falls and reduce frailty and mortality.
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Multicomponent exercise and PRT potentially ameliorate frailty and reduce falls in institutionalized older adults.
“and potentially ameliorate frailty and reduce falls [84,109,240].”
From Global consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR) (2025) · cites this paper as [240]
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Additional file 3 of Reversing frailty in older adults: a scoping review
Kolle, A. T., Lewis, K. B., Lalonde, M., & Backman, C. (2024) · Figshare · doi:10.6084/m9.figshare.26641732
Additional file 2 of Reversing frailty in older adults: a scoping review
Kolle, A. T., Lewis, K. B., Lalonde, M., & Backman, C. (2024) · Figshare · doi:10.6084/m9.figshare.26641729
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Additional file 4 of Reversing frailty in older adults: a scoping review
Kolle, A. T., Lewis, K. B., Lalonde, M., & Backman, C. (2024) · Figshare · doi:10.6084/m9.figshare.26641735
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- Authors
- Arrieta, H., Rezola‐Pardo, C., Gil, S. M., Virgala, J., Iturburu, M., Antón, I., González‐Templado, V., Irazusta, J., & Rodriguez‐Larrad, A.
- Affiliations
- University of the Basque Country (ES)
- Matia Fundazioa (ES)
- Caser Betharram Hondarribia Spain
- Corresponding author
- Arrieta, Haritz
- ORCID
- Venue
- Journal of the American Geriatrics Society
- Publisher
- Wiley
- Published
- 2019-03-19
- Volume
- 67
- Issue
- 6
- Pages
- 1145-1151
- ISSN
- 0002-8614 (ISSN-L)
- 1532-5415
- OpenAlex
- W2924538529
- Cited by
- 111
- References
- 46
- Citations by year
- 2026: 10 · 2025: 17 · 2024: 33 · 2023: 9 · 2022: 17 · 2021: 16 · 2020: 4 · 2019: 5
- FWCI
- 5.53
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- Journal of the American Geriatrics Society (publishedVersion)
- PubMed (publishedVersion)
- Communities in ADDI (University of the Basque Country) (submittedVersion, other-oa)
- Hispana (submittedVersion, other-oa)
- Funders
- Eusko Jaurlaritza (ELKARTEK16/57, ELKARTEK17/61, RIS16/07, SAN17/11)
- Topics
- Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
- Health Sciences › Health Professions › General Health Professions › Geriatric Care and Nursing Homes
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Keywords
- multicomponent exercise, frailty, nursing home residents, older adults, fall prevention, mortality, functional decline, individualized exercise program, exercise intensity, Fried frailty phenotype
- MeSH terms
- Accidental Falls, Aged, Female, Humans, Male, Mortality, Nursing Homes, Surveys and Questionnaires, Spain, Exercise, Single-Blind Method, Frail Elderly
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