The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Artificial intelligence as the next step towards precision pathology
Open accessAbstract
Pathology is the cornerstone of cancer care. The need for accuracy in histopathologic diagnosis of cancer is increasing as personalized cancer therapy requires accurate biomarker assessment. The appearance of digital image analysis holds promise to improve both the volume and precision of histomorphological evaluation. Recently, machine learning, and particularly deep learning, has enabled rapid advances in computational pathology. The integration of machine learning into routine care will be a milestone for the healthcare sector in the next decade, and histopathology is right at the centre of this revolution. Examples of potential high‐value machine learning applications include both model‐based assessment of routine diagnostic features in pathology, and the ability to extract and identify novel features that provide insights into a disease. Recent groundbreaking results have demonstrated that applications of machine learning methods in pathology significantly improves metastases detection in lymph nodes, Ki67 scoring in breast cancer, Gleason grading in prostate cancer and tumour‐infiltrating lymphocyte (TIL) scoring in melanoma. Furthermore, deep learning models have also been demonstrated to be able to predict status of some molecular markers in lung, prostate, gastric and colorectal cancer based on standard HE slides. Moreover, prognostic (survival outcomes) deep neural network models based on digitized HE slides have been demonstrated in several diseases, including lung cancer, melanoma and glioma. In this review, we aim to present and summarize the latest developments in digital image analysis and in the application of artificial intelligence in diagnostic pathology.
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Cited by
McGenity, C., Clarke, E. L., Jennings, C., Matthews, G., Cartlidge, C., Freduah-Agyemang, H., Stocken, D. D., & Treanor, D. (2024) · npj Digital Medicine · doi:10.1038/s41746-024-01106-8 · Cited by 290
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Application of Artificial Intelligence in Medicine: An Overview
Liu, P.-R., Lu, L., Zhang, J.-Y., Huo, T.-T., Liu, S.-X., & Ye, Z.-W. (2021) · Current Medical Science · doi:10.1007/s11596-021-2474-3 · Cited by 258
Improved breast cancer histological grading using deep learning
Wang, Y., Acs, B., Robertson, S., Liu, B., Solorzano, L., Wählby, C., Hartman, J., & Rantalainen, M. (2022) · Annals of Oncology · doi:10.1016/j.annonc.2021.09.007 · Cited by 211
Self-citationA bird's-eye view of deep learning in bioimage analysis
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Metadata
- Authors
- Acs, B., Rantalainen, M., & Hartman, J.
- Venue
- Journal of Internal Medicine
- Publisher
- Wiley
- Published
- 2020-03-03
- Volume
- 288
- Issue
- 1
- Pages
- 62-81
- ISSN
- 0954-6820 (ISSN-L)
- 1365-2796
- OpenAlex
- W3009926465
- Cited by
- 450
- References
- 18
- FWCI
- 20.55
- Type
- journal article
- Language
- en
- Open access
- hybrid
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