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Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy
Open accessAbstract
A relatively high mortality of severe coronavirus disease 2019 (COVID‐19) is worrying, and the application of heparin in COVID‐19 has been recommended by some expert consensus because of the risk of disseminated intravascular coagulation and venous thromboembolism. However, its efficacy remains to be validated.
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., Zhang, L., Fan, G., Xu, J., Gu, X., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30183-5 · Cited by 48,884
The third international consensus definitions for sepsis and septic shock (Sepsis-3).
Singer, M., Deutschman, C. S., Seymour, C. W., Shankar-Hari, M., Annane, D., Bauer, M., Bellomo, R., Bernard, G. R., Chiche, J.-D., Coopersmith, C. M., et al. (2016) · JAMA · doi:10.1001/jama.2016.0287 · Cited by 28,250
Chen, N., Zhou, M., Dong, X., Qu, J., Gong, F., Han, Y., Qiu, Y., Wang, J., Liu, Y., Wei, Y., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30211-7 · Cited by 21,415
Vincent, J. L., Moreno, R., Takala, J., Willatts, S., De Mendonça, A., Bruining, H., Reinhart, C. K., Suter, P. M., & Thijs, L. G. (1996) · Intensive Care Medicine · doi:10.1007/bf01709751 · Cited by 11,674
Research works printed but not linked: 20
- Tang, 2020, Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia, J Thromb Haemost, 10.1111/jth.14768 · DOI · Paper page
- 2020, Comprehensive treatment and management of coronavirus disease 2019: expert consensus statement from Shanghai (in Chinese), Chin J Infect Dis, 38
- Iba, 2019, Diagnosis and management of sepsis‐induced coagulopathy and disseminated intravascular coagulation, J Thromb Haemost, 17, 1989, 10.1111/jth.14578 · DOI · Paper page
- Iba, 2017, New criteria for sepsis‐induced coagulopathy (SIC) following the revised sepsis definition: a retrospective analysis of a nationwide survey, BMJ Open, 7, 10.1136/bmjopen-2017-017046 · DOI · Paper page
- National Health Commission of China. The diagnosis and treatment plan for the novel coronavirus disease (the seventh edition). 2020.
- Venclauskas, 2018, European guidelines on perioperative venous thromboembolism prophylaxis: day surgery and fast‐track surgery, Eur J Anaesthesiol, 35, 134, 10.1097/EJA.0000000000000706 · doi:10.1097/eja.0000000000000706
- Levi, 2017, Coagulation and sepsis, Thromb Res, 149, 38, 10.1016/j.thromres.2016.11.007 · DOI · Paper page
- Schmitt, 2019, Acute fibrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study, Ann Intensive Care, 9, 19, 10.1186/s13613-019-0499-6 · DOI · Paper page
- Gupta, 2019, The stimulation of thrombosis by hypoxia, Thromb Res, 181, 77, 10.1016/j.thromres.2019.07.013 · DOI · Paper page
- Poterucha, 2017, More than an anticoagulant: do heparins have direct anti‐inflammatory effects?, Thromb Haemost, 117, 437, 10.1160/TH16-08-0620 · DOI · Paper page
- Stein, 2004, Pulmonary thromboembolism in Asians/Pacific Islanders in the United States: analysis of data from the National Hospital Discharge Survey and the United States Bureau of the Census, Am J Med, 116, 435, 10.1016/j.amjmed.2003.11.020 · DOI · Paper page
- Zakai, 2011, Racial differences in venous thromboembolism, J Thromb Haemost, 9, 1877, 10.1111/j.1538-7836.2011.04443.x · DOI
- Aikawa, 2011, Thrombomodulin alfa in the treatment of infectious patients complicated by disseminated intravascular coagulation: subanalysis from the phase 3 trial, Shock, 35, 349, 10.1097/SHK.0b013e318204c019 · doi:10.1097/shk.0b013e318204c019
- Liu, 2014, Low‐dose heparin as treatment for early disseminated intravascular coagulation during sepsis: a prospective clinical study, Exp Ther Med, 7, 604, 10.3892/etm.2013.1466 · doi:10.3892/etm.2013.1466
- Nishida, 2018, The Japanese clinical practice guidelines for management of sepsis and septic shock 2016 (J‐SSCG 2016), Acute Med Surg, 5, 3, 10.1002/ams2.322 · DOI
- Umemura, 2016, Efficacy and safety of anticoagulant therapy in three specific populations with sepsis: a meta‐analysis of randomized controlled trials, J Thromb Haemost, 14, 518, 10.1111/jth.13230 · DOI · Paper page
- Iba, 2014, Anticoagulant therapy for sepsis‐associated disseminated intravascular coagulation: the view from Japan, J Thromb Haemost, 12, 1010, 10.1111/jth.12596 · DOI
- Menter, 2017, Platelet "first responders" in wound response, cancer, and metastasis, Cancer Metastasis Rev, 36, 199, 10.1007/s10555-017-9682-0 · DOI · Paper page
- Sun, 2009, Reduced thrombin generation increases host susceptibility to group A streptococcal infection, Blood, 113, 1358, 10.1182/blood-2008-07-170506 · DOI
- Dong, 2020, Discovering drugs to treat coronavirus disease 2019 (COVID‐19), Drug Discov Ther, 14, 58, 10.5582/ddt.2020.01012 · DOI · Paper page
Cited by
Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19
Ackermann, M., Verleden, S. E., Kuehnel, M., Haverich, A., Welte, T., Laenger, F., Vanstapel, A., Werlein, C., Stark, H., Tzankov, A., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2015432 · Cited by 5,613
Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages
Merad, M., & Martin, J. C. (2020) · Nature Reviews Immunology · doi:10.1038/s41577-020-0331-4 · Cited by 2,472
COVID-19 and its implications for thrombosis and anticoagulation
Connors, J. M., & Levy, J. H. (2020) · Blood · doi:10.1182/blood.2020006000 · Cited by 2,369
Lodigiani, C., Iapichino, G., Carenzo, L., Cecconi, M., Ferrazzi, P., Sebastian, T., Kucher, N., Studt, J.-D., Sacco, C., Bertuzzi, A., et al. (2020) · Thrombosis Research · doi:10.1016/j.thromres.2020.04.024 · Cited by 2,054
Coagulation abnormalities and thrombosis in patients with COVID-19
Levi, M., Thachil, J., Iba, T., & Levy, J. H. (2020) · The Lancet Haematology · doi:10.1016/s2352-3026(20)30145-9 · Cited by 1,544
Metadata
- Authors
- Tang, N., Bai, H., Chen, X., Gong, J., Li, D., & Sun, Z.
- Venue
- Journal of Thrombosis and Haemostasis
- Publisher
- Elsevier BV
- Published
- 2020-05
- Volume
- 18
- Issue
- 5
- Pages
- 1094-1099
- ISSN
- 1538-7836 (ISSN-L)
- OpenAlex
- W3013486442
- Cited by
- 3,559
- References
- 4
- FWCI
- 100.92
- Type
- journal article
- Language
- en
- Open access
- bronze
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 916 d)
- Funders
- National Mega Project on Major Infectious Disease Prevention of China (2017ZX10103005-007)
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- Tang, N., Bai, H., Chen, X., Gong, J., Li, D., & Sun, Z. (2020). Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy. Journal of Thrombosis and Haemostasis. https://doi.org/10.1111/jth.14817
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