COVID-19 Associated Pulmonary Aspergillosis
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OBJECTIVES: Patients with acute respiratory distress syndrome (ARDS) due to viral infection are at risk for secondary complications like invasive aspergillosis. Our study evaluates coronavirus disease 19 (COVID-19) associated invasive aspergillosis at a single centre in Cologne, Germany. METHODS: A retrospective chart review of all patients with COVID-19 associated ARDS admitted to the medical or surgical intensive care unit at the University Hospital of Cologne, Cologne, Germany. RESULTS: COVID-19 associated invasive pulmonary aspergillosis was found in five of 19 consecutive critically ill patients with moderate to severe ARDS. CONCLUSION: Clinicians caring for patients with ARDS due to COVID-19 should consider invasive pulmonary aspergillosis and subject respiratory samples to comprehensive analysis to detect co-infection.
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At the time of writing, there are an increasing number of reports from Europe of patients with probable or possible COVID-19 associated pulmonary aspergillosis.
“at the time of writing there are an increasing number of reports from Europe of patients with probable or possible COVID-19 associated pulmonary aspergillosis.50, 51, 52, 53, 54”
From Co-infections in people with COVID-19: a systematic review and meta-analysis. (2020) · cites this paper as [52]
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- Authors
- Koehler, P., Cornely, O. A., Böttiger, B. W., Dusse, F., Eichenauer, D. A., Fuchs, F., Hallek, M., Jung, N., Klein, F., Persigehl, T., Rybniker, J., Kochanek, M., Böll, B., & Shimabukuro‐Vornhagen, A.
- Affiliations
- University of Cologne (DE)
- Department of Radiology Medical Faculty and University Hospital Cologne University of Cologne Cologne Germany
- Corresponding author
- Koehler, Philipp
- ORCID
- Venue
- Mycoses
- Publisher
- Wiley
- Published
- 2020-05-15
- Volume
- 63
- Issue
- 6
- Pages
- 528-534
- ISSN
- 0027-5557 (ISSN-L)
- 0933-7407
- 1439-0507
- PMC
- PMC7267243
- OpenAlex
- W3019320147
- Cited by
- 547
- References
- 13
- Citations by year
- 2026: 11 · 2025: 20 · 2024: 36 · 2023: 69 · 2022: 129 · 2021: 169 · 2020: 112
- FWCI
- 15.71
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Mycoses (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Kölner Universitäts PublikationsServer (Universität zu Köln) (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Nosocomial Infections in ICU
- Keywords
- COVID-19 pandemic, SARS-CoV-2, invasive pulmonary aspergillosis, acute respiratory distress syndrome, secondary fungal infection, co-infection, critically ill patients, intensive care unit
- MeSH terms
- COVID-19, Aged, Antifungal Agents, Bronchoalveolar Lavage Fluid, Female, Galactose, Germany, Hemorrhage, Hospitals, Teaching, Humans, Intensive Care Units, Lung Diseases, Male, Mannans, Middle Aged, Nitriles, Pneumonia, Viral, Pyridines, Respiratory Distress Syndrome, Retrospective Studies, Thorax, Tomography, X-Ray Computed, Triazoles, Paramyxoviridae Infections, Coronavirus Infections, Metapneumovirus, Pulmonary Aspergillosis, Pandemics, Voriconazole
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