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Cited by 81Gastrointestinal motility and disordersGastrointestinal Bleeding Diagnosis and TreatmentGastroesophageal reflux and treatments

Validation of SmartPill® wireless motility capsule for gastrointestinal transit time: Intra‐subject variability, software accuracy and comparison with video capsule endoscopy

Diaz Tartera, H. O., Webb, D.‐L., Al‐Saffar, A. Kh., Halim, M. A., Lindberg, G., Sangfelt, P., Hellström, P. M.·2017·Neurogastroenterology & Motility
DOI 10.1111/nmo.13107
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Abstract

Background There is interest in ultimately combining endoscopy and motility assessments. Gastric emptying (GET), small bowel (SBTT), colon (CTT) and whole gut transit (WGTT) times are conveniently obtained by SmartPill ® wireless motility capsule (WMC) that records luminal pH, temperature and pressure. Reproducibility within same subjects and accuracy of software derived times (MotiliGI ® ) were investigated for diagnostic application. GET and SBTT were separately measured using video capsule endoscopy (VCE). The aim of this investigation was to assess same subject reproducibility of WMC, accuracy of software derived transit times and relate to Pillcam ® SB (small bowel) VCE motility data. Methods Seventy three healthy adults ingested a 260 kcal mixed meal followed by WMC tests. Food intake was permitted after 6 hours. Regional transit data was obtained for GET, SBTT and CTT, the sum yielding WGTT. Nineteen subjects repeated WMC tests 2 or 4 weeks later; a separate 70 underwent VCE while fasted. Key results Visually derived data from WMC yielded GET 3.46±0.27, SBTT 5.15±0.21, CTT 20.76±1.19 and WGTT 29.53±1.28 hours (mean±SEM). Pearson's correlation coefficients (r) against software derived results were: GET 0.78 (P Conclusions and inferences GET, SBTT, CTT and WGTT obtained by WMC are commensurate with literature values, including by other methods. Visually and software derived transit times have strongest correlations for CTT and WGTT. WMC yields longer GET and SBTT than VC…

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Crossref · 10.1111/nmo.13107

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  • Advanced techniques, including antroduodenal‐jejunal manometry, wireless motility capsule, gastric ultrasound, and high‐resolution electrogastrography (EGG), may provide additional pathophysiological insight, particularly in complex or mixed‐pattern cases.

    “Advanced techniques, including antroduodenal‑jejunal manometry [71–75], wireless motility capsule [76–79], gastric ultrasound [80–82], and high‑resolution electrogastrography (EGG) [83–87] may provide additional pathophysiological insight, particularly in complex or mixed‑pattern cases.”

    From Diabetic gastroparesis: pathophysiology and impact on insulin timing choices (2026) · cites this paper as [78]

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Authors
Diaz Tartera, H. O., Webb, D. ‐., Al‐Saffar, A. K., Halim, M. A., Lindberg, G., Sangfelt, P., & Hellström, P. M.
Affiliations
  • Gastroenterology and Hepatology Unit Department of Medical Sciences Uppsala University Uppsala Sweden
  • Uppsala University (SE)
  • Karolinska University Hospital (SE)
Corresponding author
Webb, D.‐L.
ORCID
Venue
Neurogastroenterology & Motility
Publisher
Wiley
Published
2017-05-19
Volume
29
Issue
10
Pages
1-9
ISSN
  • 1350-1925 (ISSN-L)
  • 1365-2982
DOI
10.1111/nmo.13107
OpenAlex
W2615056982
Cited by
81
References
4
Citations by year
2026: 7 · 2025: 8 · 2024: 8 · 2023: 7 · 2022: 9 · 2021: 14 · 2020: 10 · 2019: 9 · 2018: 7 · 2017: 2
FWCI
8.03
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Neurogastroenterology & Motility (publishedVersion)
  • PubMed (publishedVersion)
Funders
Sveriges Läkarförbund (SLS‐503131)
Topics
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal Bleeding Diagnosis and Treatment
  • Health Sciences › Medicine › Gastroenterology › Gastroesophageal reflux and treatments
Keywords
gastrointestinal transit time, gastric emptying time, small bowel transit time, colonic transit time, whole gut transit time, capsule endoscopy, within-person variability, software accuracy
MeSH terms
Adult, Aged, Female, Gastrointestinal Motility, Gastrointestinal Transit, Humans, Male, Middle Aged, Software, Reproducibility of Results, Capsule Endoscopy, Young Adult

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