The Wireless Motility Capsule: a One-Stop Shop for the Evaluation of GI Motility Disorders
Abstract
The wireless motility and pH capsule (WMC) provides an office-based test to simultaneously assess both regional and whole gut transit. Ingestion of this non-digestible capsule capable of measuring temperature, pH, and the pressure of its immediate surroundings allows for the measurement of gastric, small bowel, and colonic transit times in an ambulatory setting. Approved by the US Food and Drug Administration for the evaluation of suspected conditions of delayed gastric emptying and the evaluation of colonic transit in chronic idiopathic constipation, WMC should be considered in suspected gastrointestinal motility disorders as it provides a single study capable of simultaneously assessing for regional, multiregional, or generalized motility disorders. Specific indications for testing with the WMC should include the evaluation of suspect cases of gastroparesis, small bowel dysmotility, and slow transit constipation, as well as symptom syndromes suggestive of a multiregional or generalized gastrointestinal transit delay.
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Advanced techniques, including antroduodenal‐jejunal manometry, wireless motility capsule, gastric ultrasound, and high‐resolution electrogastrography (EGG), may provide additional pathophysiological insight, particularly in complex or mixed‐pattern cases.
“Advanced techniques, including antroduodenal‑jejunal manometry [71–75], wireless motility capsule [76–79], gastric ultrasound [80–82], and high‑resolution electrogastrography (EGG) [83–87] may provide additional pathophysiological insight, particularly in complex or mixed‑pattern cases.”
From Diabetic gastroparesis: pathophysiology and impact on insulin timing choices (2026) · cites this paper as [76]
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“The WMC test is applied according to a standardised protocol, whereas scintigraphic emptying study protocols can vary [6].”
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“A wireless motility capsule (WMC) system is capable of measuring gastric emptying time as well as small bowel and colon transit times [8].”
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“20,21 These parameters include (Figure 1): - Pressure: The WMC measures pressure ranging from 0 to 350 mm Hg, capturing data every 0.5 s for the first 24 h and every second after that.”
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“Despite their potential significance for higher order cognitive functions (9), organs located in the abdominal cavity, such as the stomach and the intestine, are difficult to reach and probe without relying on invasive methods (10, 11).”
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- Authors
- Saad, R. J.
- Affiliations
- University of Michigan (US)
- Corresponding author
- Saad, Richard J.
- Venue
- Current Gastroenterology Reports
- Published
- 2016-02-23
- Volume
- 18
- Issue
- 3
- Pages
- 14-14
- ISSN
- 1522-8037 (ISSN-L)
- 1534-312X
- OpenAlex
- W2277312454
- Cited by
- 73
- References
- 0
- Citations by year
- 2026: 4 · 2025: 9 · 2024: 6 · 2023: 6 · 2022: 3 · 2021: 11 · 2020: 9 · 2019: 5 · 2018: 8 · 2017: 10 · 2016: 2
- FWCI
- 1.39
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Current Gastroenterology Reports (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Gastroenterology › Gastroesophageal reflux and treatments
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal Bleeding Diagnosis and Treatment
- Keywords
- gastrointestinal motility disorders, gastric emptying, colonic transit, small intestinal transit, gastroparesis, slow transit constipation, chronic idiopathic constipation
- MeSH terms
- Contraindications, Gastric Emptying, Gastrointestinal Diseases, Gastrointestinal Motility, Gastrointestinal Transit, Humans, Capsule Endoscopy
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