Deconstructing stigma as a barrier to treating DGBI: Lessons for clinicians
Open accessAbstract
Stigma, defined as social devaluation based on negative stereotypes toward a particular population, is prevalent within health care and is a common phenomenon in disorders of gut‐brain interaction (DGBI). Characteristically, DGBI including functional dyspepsia (FD) lack a structural etiology to explain symptoms, have high psychiatric co‐morbidity, and respond to neuromodulators traditionally used to treat psychopathology. As a result, these disorders are frequently and wrongly presumed to be psychiatric and carry a great deal of stigma. Stigma has profound adverse consequences for patients, including emotional distress, medication non‐adherence, barriers to accessing care, and increased symptoms. The basis for stigma dates back to the 17th Century concept of mind‐body dualism. Patients and health care providers need to understand the factors that promote stigma and methods to ameliorate it. In this minireview, we address the data presented in Yan et al.'s (Neurogastroenterol Motil, 2020, e13956). We offer concrete solutions for clinicians to mitigate the impact of stigma to optimize treatment adherence and clinical outcomes for patients with DGBI.
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Butt, M. F., Benninga, M. A., & Corsetti, M. (2024) · Neurogastroenterology & Motility · doi:10.1111/nmo.14922
Humphrey, G., Law, M., Keane, C., Andrews, C. N., Gharibans, A. A., & O’Grady, G. (2024) · medRxiv · doi:10.1101/2024.10.15.24315420
Soldaini, C., Santonicola, A., Ruggiero, L., Caloro, A., Leo, L. D., Pallotta, N., & Iovino, P. (2025) · Scientific Reports · doi:10.1038/s41598-025-93576-3
Podcasts zur Psychoedukation bei Reizdarmsyndrom: Eine Mixed-methods-Analyse
Gerhold, P., Löwe, B., Huber, S., & Weigel, A. (2025) · Zeitschrift für Gastroenterologie · doi:10.1055/a-2550-9549
Approach to the Child With a Disorder of Gut-Brain Interaction
Jerson, B., & Baker, C. C. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-11760-2.00007-0
Topics, Patient Satisfaction Focused Medical Care
Yamamoto, S., & Kasugai, K. (2026) · Springer eBooks · doi:10.1007/978-981-95-6974-8_87
Palibroda, N. M., & Zlotar, O. V. (2026) · INTERNATIONAL NEUROLOGICAL JOURNAL · doi:10.22141/2224-0713.22.4.2026.1245
- Authors
- Feingold, J. H., & Drossman, D. A.
- Affiliations
- Icahn School of Medicine at Mount Sinai (US)
- University of North Carolina at Chapel Hill (US)
- Corresponding author
- Feingold, Jordyn H.
- Venue
- Neurogastroenterology & Motility
- Publisher
- Wiley
- Published
- 2021-01-23
- Volume
- 33
- Issue
- 2
- Pages
- e14080-e14080
- ISSN
- 1350-1925 (ISSN-L)
- 1365-2982
- PMC
- PMC8091160
- OpenAlex
- W3122942910
- Cited by
- 60
- References
- 46
- Citations by year
- 2026: 10 · 2025: 10 · 2024: 15 · 2023: 7 · 2022: 6 · 2021: 12
- FWCI
- 1.91
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Neurogastroenterology & Motility (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (TL1TR001434)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Keywords
- stigma, functional gastrointestinal disorders, functional dyspepsia, mind-body dualism, psychiatric comorbidity, neuromodulators, medication adherence, barriers to care
- MeSH terms
- Gastrointestinal Diseases, Humans, Social Stigma
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