The DOI matches its Crossref record; 76 of the 76 references it cites were found in a registry or an index.
A core function of EDS1 with PAD4 is to protect the salicylic acid defense sector in Arabidopsis immunity
Open accessAbstract
Summary: Plant defenses induced by salicylic acid (SA) are vital for resistance against biotrophic pathogens. In basal and receptor‐triggered immunity, SA accumulation is promoted by Enhanced Disease Susceptibility1 with its co‐regulator Phytoalexin Deficient4 (EDS1/PAD4). Current models position EDS1/PAD4 upstream of SA but their functional relationship remains unclear. In a genetic and transcriptomic analysis of Arabidopsis autoimmunity caused by constitutive or conditional EDS1/PAD4 overexpression, intrinsic EDS1/PAD4 signaling properties and their relation to SA were uncovered. A core EDS1/PAD4 pathway works in parallel with SA in basal and effector‐triggered bacterial immunity. It protects against disabled SA‐regulated gene expression and pathogen resistance, and is distinct from a known SA‐compensatory route involving MAPK signaling. Results help to explain previously identified EDS1/PAD4 regulated SA‐dependent and SA‐independent gene expression sectors. Plants have evolved an alternative route for preserving SA‐regulated defenses against pathogen or genetic perturbations. In a proposed signaling framework, EDS1 with PAD4, besides promoting SA biosynthesis, maintains important SA‐related resistance programs, thereby increasing robustness of the innate immune system.
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Salicylic acid, a multifaceted hormone to combat disease
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Yuan, M., Ngou, B. P. M., Ding, P., & Xin, X.-F. (2021) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2021.102030 · Cited by 915
Fatty Acid– and Lipid-Mediated Signaling in Plant Defense
Lim, G.-H., Singhal, R., Kachroo, A., & Kachroo, P. (2017) · Annual Review of Phytopathology · doi:10.1146/annurev-phyto-080516-035406 · Cited by 448
Monoterpenes Support Systemic Acquired Resistance within and between Plants
Riedlmeier, M., Ghirardo, A., Wenig, M., Knappe, C., Koch, K., Georgii, E., Dey, S., Parker, J. E., Schnitzler, J.-P., & Vlot, A. C. (2017) · The Plant Cell · doi:10.1105/tpc.16.00898 · Cited by 323
Self-citationA Coevolved EDS1-SAG101-NRG1 Module Mediates Cell Death Signaling by TIR-Domain Immune Receptors
Lapin, D., Kovacova, V., Sun, X., Dongus, J. A., Bhandari, D., von Born, P., Bautor, J., Guarneri, N., Rzemieniewski, J., Stuttmann, J., et al. (2019) · The Plant Cell · doi:10.1105/tpc.19.00118 · Cited by 303
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Metadata
- Authors
- Cui, H., Gobbato, E., Kracher, B., Qiu, J., Bautor, J., & Parker, J. E.
- Venue
- New Phytologist
- Publisher
- Wiley
- Published
- 2016-11-15
- Volume
- 213
- Issue
- 4
- Pages
- 1802-1817
- ISSN
- 0028-646X (ISSN-L)
- 1469-8137
- OpenAlex
- W2557012018
- Cited by
- 299
- References
- 76
- FWCI
- 20.66
- Type
- journal article
- Language
- en
- Open access
- bronze
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