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Caffeine improves various aspects of athletic performance in adolescents independent of their 163 C > A CYP1A2 genotypes
Abstract
Purpose: The purpose of this study was to investigate whether variations in 163 C > A CYP1A2 genotypes (rs 762 551) (AA, AC, and CC) modify the ergogenic effects of caffeine (CAF) on strength, power, muscular endurance, agility, and endurance in adolescent athletes. Methods: One hundred adolescents (age = 15 ± 2 years) were recruited. Participants ingested CAF (6 mg.kg −1 ) or placebo (PLA, 300 mg of cellulose) 1 hour before performing a sequence of physical tests: handgrip strength, vertical jumps, agility test, sit‐ups, push‐ups, and the Yo‐Yo intermittent recovery test level 1 (Yo‐Yo IR1). Results: Compared to PLA, CAF enhanced ( P < .05) sit‐up (CAF = 37 ± 9; PLA = 35 ± 8 repetitions) and push‐up repetitions (CAF = 26 ± 11; PLA = 24 ± 11 repetitions), and increased distance covered in Yo‐Yo IR1 test (CAF = 1010.4 ± 378.9; PLA = 903.2 ± 325.7 m). There was no influence of CAF on handgrip strength (CAF = 35.1 ± 8.9; PLA = 33.7 ± 8.7 kgf), countermovement jump height (CAF = 49.3 ± 12.6; PLA = 47.9 ± 13.8 cm), spike jump height (CAF = 54.2 ± 13.6; PLA = 52.9 ± 14.5 cm), and time in agility test (CAF = 15.8 ± 1.1; PLA = 15.9 ± 1.3 s, P > .05). When present, the ergogenic effect of CAF was not dependent of genotype. Conclusion: CAF improves muscular endurance and aerobic performance in adolescent athletes, regardless of their 163 C > A CYP1A2 genotype.
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“Table 1 shows four studies of the effect of coffee on the athletic performance of young people ≤18 years. These studies concluded that caffeine enhances the intensity and duration of sports activity and also reduces the feeling of pain and fatigue during exercise (27–30).”
From Junior athletes’ nutritional demands: a narrative review of consumption and prevalence of eating disorders (2024) · cites this paper as [27]
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Cited by
Caffeine, CYP1A2 Genotype, and Exercise Performance: A Systematic Review and Meta-Analysis
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Metadata
- Authors
- Spineli, H., Pinto, M. P., Dos Santos, B. P., Lima‐Silva, A. E., Bertuzzi, R., Gitaí, D. L. G., & de Araujo, G. G.
- Affiliations
- Postgraduate Program in Nutrition – PPGNUT Federal University of Alagoas Alagoas Brazil
- Postgraduate Program in Health Sciences – PPGCS Federal University of Alagoas Alagoas Brazil
- Human Performance Research Group Technological Federal University of Parana Parana Brazil
- Endurance Performance Research Group (GEDAE‐USP) School of Physical Education and Sport University of São Paulo São Paulo Brazil
- ORCID
- Venue
- Scandinavian Journal of Medicine & Science in Sports
- Publisher
- Wiley
- Published
- 2020-07-13
- Volume
- 30
- Issue
- 10
- Pages
- 1869-1877
- ISSN
- 0905-7188
- 1600-0838
- Cited by
- 37
- References
- 10
- Language
- en
- Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (60030 1121/2015)
- Fundação de Amparo à Pesquisa do Estado de Alagoas (60030 1121/2015)
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