The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Successful lung transplantation for chronic Mycobacterium abscessus infection in advanced cystic fibrosis, a case series
Open accessAbstract
Pulmonary Mycobacterium abscessus infection in cystic fibrosis (CF) patients is difficult to treat and considered a contra‐indication for lung transplantation in most centers. We present four CF patients with chronic pulmonary M abscessus infection, in whom lung transplantation was performed. Through intensive treatment before transplantation, we achieved control of the infection in all but one patient. After a mean of 16 months of follow up, 3 patients are doing well, without evidence of local or disseminated recurrence. One patient died early post‐transplant due to an unrelated cause. These findings support the possibility of lung transplantation with favorable outcome in CF patients with M abscessus infection.
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Increasing evidence shows that intensive treatment and surveillance before and after lung transplant may lead to better results.
“Increasing evidence shows that intensive treatment and surveillance pre and post lung transplant may lead to better results.(66–69)”
From Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation. (2021) · cites this paper as [66]
The Discussion reports favorable outcomes in three of four cystic fibrosis patients with M. abscessus infection and describes intensive treatment before and after transplantation. The Accepted Article passages describe frequent pre-transplant cultures and routine post-transplant surveillance bronchoscopy. The paper does not establish that surveillance improved outcomes, and its findings are limited to this patient group rather than lung transplant recipients generally. (LLM, conf=0.82)
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Cites
Griffith, D. E., Aksamit, T., Brown-Elliott, B. A., Catanzaro, A., Daley, C., Gordin, F., Holland, S. M., Horsburgh, R., Huitt, G., Iademarco, M. F., et al. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200604-571st · Cited by 6,110
Weill, D., Benden, C., Corris, P. A., Dark, J. H., Davis, R. D., Keshavjee, S., Lederer, D. J., Mulligan, M. J., Patterson, G. A., Singer, L. G., et al. (2015) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2014.06.014 · Cited by 1,329
Self-citationFloto, R. A., Olivier, K. N., Saiman, L. M., Daley, C. L., Herrmann, J., Nick, J. A., Noone, P. G., Bilton, D., Corris, P. A., Gibson, R. L., et al. (2015) · Thorax · doi:10.1136/thoraxjnl-2015-207360 · Cited by 467
Chronic Mycobacterium abscessus infection and lung function decline in cystic fibrosis
Esther, C. R., Esserman, D. A., Gilligan, P., Kerr, A., & Noone, P. G. (2010) · Journal of Cystic Fibrosis · doi:10.1016/j.jcf.2009.12.001 · Cited by 410
Randomized Trial of Liposomal Amikacin for Inhalation in Nontuberculous Mycobacterial Lung Disease
Olivier, K. N., Griffith, D. E., Eagle, G. L., McGinnis, J. P., Micioni, L., Liu, K., Daley, C. L., Winthrop, K. L., Ruoss, S. J., Addrizzo-Harris, D. J., et al. (2016) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201604-0700oc · Cited by 255
Philley, J. V., Wallace, R. J., Benwill, J. L., Taskar, V. S., Brown‐Elliott, B. A., Thakkar, F., Aksamit, T. R., & Griffith, D. E. (2015) · CHEST Journal · doi:10.1378/chest.14-2764 · Cited by 225
van Ingen, J., Totten, S. E., Helstrom, N. K., Heifets, L. B., Boeree, M. J., & Daley, C. L. (2012) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01505-12 · Cited by 172
Qvist, T., Taylor-Robinson, D. C., Waldmann, E., Olesen, H. V., Hansen, C. R., Mathiesen, I. H. M., Høiby, N., Katzenstein, T. L., Smyth, R. L., Diggle, P. J., et al. (2015) · Journal of Cystic Fibrosis · doi:10.1016/j.jcf.2015.09.007 · Cited by 148
Mycobacterium abscessus Infections in Lung Transplant Recipients: The International Experience
Chernenko, S., Humar, A., Hutcheon, M., Chow, C., Chaparro, C., Keshavjee, S. H., & Singer, L. G. (2006) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2006.09.003 · Cited by 110
Lobo, L. J., Chang, L. C., Esther, C. R., Gilligan, P. H., Tulu, Z., & Noone, P. G. (2013) · Clinical Transplantation · doi:10.1111/ctr.12140 · Cited by 108
Taylor, J. L., & Palmer, S. M. (2006) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2006.04.003 · Cited by 91
Qvist, T., Pressler, T., Thomsen, V. O., Skov, M., Iversen, M., & Katzenstein, T. L. (2013) · Transplantation Proceedings · doi:10.1016/j.transproceed.2012.02.035 · Cited by 76
High-dose vitamin D after lung transplantation: A randomized trial
Vos, R., Ruttens, D., Verleden, S. E., Vandermeulen, E., Bellon, H., Herck, A. V., Sacreas, A., Heigl, T., Schaevers, V., Raemdonck, D. E. V., et al. (2017) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2017.03.008 · Cited by 35
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Leard, L. E., Holm, A. M., Valapour, M., Glanville, A. R., Attawar, S., Aversa, M., Campos, S. V., Christon, L. M., Cypel, M., Dellgren, G., et al. (2021) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2021.07.005 · Cited by 821
Shah, P. D., Lowery, E. M., Chaparro, C., Visner, G. A., Hempstead, S. E., Abraham, J. M., Bhakta, Z. N., Carroll, M., Christon, L., Danziger‐Isakov, L. A., et al. (2021) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2021.04.011 · Cited by 44
Nontuberculous Mycobacterial Infections in Cystic Fibrosis.
Martiniano, S., Nick, J., & Daley, C. (2022) · Clinics in Chest Medicine · doi:10.1016/j.ccm.2022.06.010 · Cited by 32
Kavaliūnaitė, E., Harris, K., Aurora, P., Dixon, G. L. J., Shingadia, D. V., Muthialu, N., & Spencer, H. (2020) · Transplant Infectious Disease · doi:10.1111/tid.13274 · Cited by 27
Wetzstein, N., Diricks, M., Kohl, T. A., Wichelhaus, T. A., Andres, S., Paulowski, L., Schwarz, C., Lewin, A., Kehrmann, J., Kahl, B. C., et al. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.01714-22 · Cited by 28
de Ruyck, J., Dupont, C., Lamy, E., Moigne, V. L., Biot, C., Guérardel, Y., Herrmann, J., Blaise, M., Grassin‐Delyle, S., Kremer, L., et al. (2020) · ChemistryOpen · doi:10.1002/open.202000042 · Cited by 19
Charoensutthivarakul, S., Thomas, S. E., Curran, A., Brown, K., Belardinelli, J. M., Whitehouse, A., Acebrón-García-de-Eulate, M., Sangan, J., Gramani, S. G., Jackson, M., et al. (2022) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.1c00432 · Cited by 16
Lung Transplantation in a New Era in the Field of Cystic Fibrosis
Huang, W., Smith, A., Korotun, M., Iacono, A. T., & Wang, J. (2023) · Life · doi:10.3390/life13071600 · Cited by 15
“Nonetheless, favorable outcomes have been reported in PwCF who are colonized with Mycobacterium abscessus and are lung transplantation recipients [54].”
BackgroundCystic Fibrosis-Related Nontuberculous Mycobacterial Pulmonary Disease
Baird, T., & Bell, S. C. (2023) · Clinics in Chest Medicine · doi:10.1016/j.ccm.2023.06.008 · Cited by 14
Nontuberculous mycobacteria in solid organ transplant
Anjan, S., & Morris, M. I. (2019) · Current Opinion in Organ Transplantation · doi:10.1097/mot.0000000000000665 · Cited by 11
The Lung Transplant Candidate, Indications, Timing, and Selection Criteria
Mannem, H. C., Aversa, M. M., Keller, T., & Kapnadak, S. G. (2023) · Clinics in Chest Medicine · doi:10.1016/j.ccm.2022.10.001 · Cited by 10
Update on Lung Transplantation for Cystic Fibrosis
Pilewski, J. M. (2022) · Clinics in Chest Medicine · doi:10.1016/j.ccm.2022.07.002 · Cited by 8
Ueda, Y., Okamoto, T., Sato, Y., Hayashi, A., Takahashi, T., Kamada, K., Honda, S., & Hotta, K. (2022) · Journal of Nephrology · doi:10.1007/s40620-021-01244-2 · Cited by 5
Screening of donors and recipients for infections prior to solid organ transplantation
Nanayakkara, D. D., & Schaenman, J. M. D. (2019) · Current Opinion in Organ Transplantation · doi:10.1097/mot.0000000000000671 · Cited by 5
Pretransplant screening for infections in lung and heart transplant candidates
Riunga, F., Cervera, C., & Kabbani, D. (2025) · JHLT Open · doi:10.1016/j.jhlto.2025.100409 · Cited by 3
Lung Transplantation: Selection of Candidates
Thomas, C., Williams, M., & Shlobin, O. A. (2023) · OBM Transplantation · doi:10.21926/obm.transplant.2304197 · Cited by 2
Evaluation of Candidates for Lung Transplant—A Review of Patient-Specific Risk Factors
Leard, L. E. (2024) · Current Pulmonology Reports · doi:10.1007/s13665-024-00339-y · Cited by 3
Albert, J. D., Daley, C. L., & Lin, P. L. (2024) · Journal of the Pediatric Infectious Diseases Society · doi:10.1093/jpids/piae003 · Cited by 1
Yanagisawa, A., Takimoto, T., Kurahara, Y., Tsuyuguchi, K., Yoshida, S., Hirose, M., Inoue, Y., & Arai, T. (2023) · Internal Medicine · doi:10.2169/internalmedicine.2847-23 · Cited by 1
“However, when proactive management and surveillance strategies are utilized, lung transplant recipients with MABS infections show a low incidence of recurrent infections and excellent survival rates (24-27).”
BackgroundClinical papers of the year 2018 – Cystic fibrosis
Balfour-Lynn, I. M. (2019) · Paediatric Respiratory Reviews · doi:10.1016/j.prrv.2019.03.008 · Cited by 1
Multiresistant organisms: bacteria and beyond
Solé, A. (2022) · Current Opinion in Organ Transplantation · doi:10.1097/mot.0000000000000976 · Cited by 1
Emerging Transplant Infections: Cystic Fibrosis
Mohamedaly, O. H., & Johnson, C. A. (2021) · Springer eBooks · doi:10.1007/978-3-030-25869-6_60 · Cited by 1
Emerging Transplant Infections: Cystic Fibrosis
Mohamedaly, O. H., & Johnson, C. A. (2020) · Springer eBooks · doi:10.1007/978-3-030-01751-4_60-1
Lung Transplantation in Patients with Cystic Fibrosis
Mohite, P. N., Dave, K., Reed, A. K., & Simon, A. R. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.94523
Shah, P. D., Lowery, E. M., Chaparro, C., Visner, G. A., Hempstead, S. E., Abraham, J. M., Bhakta, Z. N., Carroll, M., Christon, L., Danziger‐Isakov, L. A., et al. (2021) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2021.04.012
RetractedLung Transplantation: Recipient Selection
Glanville, A. R., & Ainge‐Allen, H. W. (2020) · Elsevier eBooks · doi:10.1016/b978-0-08-102723-3.00082-2
Lung Transplantation for Cystic Fibrosis
Pilewski, J. M. (2020) · Respiratory medicine · doi:10.1007/978-3-030-42382-7_12
(2019) · Reactions Weekly · doi:10.1007/s40278-019-62135-5
Bitterman, R., Soualhine, H., Akochy, P., Poirier, C. D., Ferraro, P., Kabbani, D., Hirji, A. S., Tyrrell, G. J., Bergeron, C., Levy, R. D., et al. (2025) · Transplant Infectious Disease · doi:10.1111/tid.70003
“…with intensive antimicrobial therapy before transplantation to reduce the mycobacterial burden (aiming for negative AFB smears), intraoperative antimicrobial pleural irrigation, aseptic measures before donor organ implantation, and prolonged post-operative antimicrobial therapy [24, 25, 27].”
Lung transplant in people with cystic fibrosis and nontuberculous mycobacteria infection
Safavi, S., Smith, S. J., Jahnke, N., Stewart, I., Watson, S. A., Prayle, A., Smyth, A. R., & Fibrosis, C. C. (2026) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd016200
Metadata
- Authors
- Raats, D., Lorent, N., Saegeman, V., Vos, R., van Ingen, J., Verleden, G., Van Raemdonck, D., & Dupont, L.
- Affiliations
- Universitair Ziekenhuis Leuven (BE)
- Department of Medical Microbiology Radboud University Medical Center Nijmegen The Netherlands
- Department of Thoracic surgery University Hospitals Leuven Leuven Belgium
- Corresponding author
- Raats, Daan
- Venue
- Transplant Infectious Disease
- Publisher
- Wiley
- Published
- 2019-01-13
- Volume
- 21
- Issue
- 2
- Pages
- e13046-e13046
- ISSN
- 1398-2273 (ISSN-L)
- 1399-3062
- OpenAlex
- W2907848968
- Semantic Scholar
- 5ae0d746f609387c6956bbda7d5dc3cf1d79a126
- Cited by
- 30
- References
- 13
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 5 · 2022: 6 · 2021: 5 · 2020: 5 · 2019: 4
- FWCI
- 2.73
- Type
- journal article
- Language
- en
- Open access
- green
- lirias.kuleuven.be
- Licence
- Locations
- Transplant Infectious Disease (publishedVersion)
- PubMed (publishedVersion)
- Lirias (submittedVersion, other-oa)
- Radboud Repository (Radboud University) (submittedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Mycobacterium research and diagnosis
- Health Sciences › Medicine › Surgery › Transplantation: Methods and Outcomes
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cystic Fibrosis Research Advances
- Keywords
- lung transplantation, Mycobacterium abscessus, nontuberculous mycobacterial infection, cystic fibrosis, chronic lung infection, post-transplant outcomes
- MeSH terms
- Adult, Anti-Bacterial Agents, Chronic Disease, Cystic Fibrosis, Female, Humans, Lung, Male, Mycobacterium Infections, Nontuberculous, Nontuberculous Mycobacteria, Lung Transplantation, Young Adult
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