Signaling mechanisms in abscisic acid-mediated stomatal closure
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Summary: The plant hormone abscisic acid (ABA) plays a central role in the regulation of stomatal movements under water‐deficit conditions. The identification of ABA receptors and the ABA signaling core consisting of PYR/PYL/RCAR ABA receptors, PP2C protein phosphatases and SnRK2 protein kinases has led to studies that have greatly advanced our knowledge of the molecular mechanisms mediating ABA‐induced stomatal closure in the past decade. This review focuses on recent progress in illuminating the regulatory mechanisms of ABA signal transduction, and the physiological importance of basal ABA signaling in stomatal regulation by CO 2 and, as hypothesized here, vapor‐pressure deficit. Furthermore, advances in understanding the interactions of ABA and other stomatal signaling pathways are reviewed here. We also review recent studies investigating the use of ABA signaling mechanisms for the manipulation of stomatal conductance and the enhancement of drought tolerance and water‐use efficiency of plants.
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The Competition between Liquid and Vapor Transport in Transpiring Leaves
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EAR1 Negatively Regulates ABA Signaling by Enhancing 2C Protein Phosphatase Activity
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A new, vapour‐phase mechanism for stomatal responses to humidity and temperature
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A ligand-independent origin of abscisic acid perception
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Leveraging abscisic acid receptors for efficient water use in Arabidopsis
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FERONIA Receptor Kinase at the Crossroads of Hormone Signaling and Stress Responses
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Abscisic Acid Transport and Homeostasis in the Context of Stomatal Regulation
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Self-citationFarnesylation mediates brassinosteroid biosynthesis to regulate abscisic acid responses
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Abscisic Acid Activates a 48-Kilodalton Protein Kinase in Guard Cell Protoplasts
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Self-citationFern Stomatal Responses to ABA and CO 2 Depend on Species and Growth Conditions
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CARK1 mediates ABA signaling by phosphorylation of ABA receptors
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Phosphoproteomic Analyses Reveal Early Signaling Events in the Osmotic Stress Response
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Self-citationA Raf-like protein kinase BHP mediates blue light-dependent stomatal opening
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Archetypal Roles of an Abscisic Acid Receptor in Drought and Sugar Responses in Liverworts
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A new discrete dynamic model of ABA-induced stomatal closure predicts key feedback loops
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Arabidopsis ALIX Regulates Stomatal Aperture and Turnover of Abscisic Acid Receptors
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Stomatal responses to humidity in isolated epidermes
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Hydrogen Sulfide Activates S-Type Anion Channel via OST1 and Ca 2+ Modules
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ROP11 GTPase is a Negative Regulator of Multiple ABA Responses in Arabidopsis
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Reconstitution of Abscisic Acid Signaling from the Receptor to DNA via bHLH Transcription Factors
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Flagged first, then by citations
Research works printed but not linked: 1
- Darwin F (1898) Observations on Stomata. Philos. Trans. R Soc. Lond., B, Biol. Sci, 190, 531– 621.
Cited by
Sorted by citations
Zong, J., Chen, P., Luo, Q., Gao, J., Qin, R., Wu, C., Lv, Q., Zhao, T., & Fu, Y. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241814398 · Cited by 27 · see citing works
- Authors
- Hsu, P., Dubeaux, G., Takahashi, Y., & Schroeder, J. I.
- Affiliations
- University of California San Diego (US)
- Corresponding author
- Schroeder, Julian I.
- Venue
- The Plant Journal
- Publisher
- Wiley
- Published
- 2020-12-09
- Volume
- 105
- Issue
- 2
- Pages
- 307-321
- ISSN
- 0960-7412 (ISSN-L)
- 1365-313X
- PMC
- PMC7902384
- OpenAlex
- W3095233590
- Cited by
- 546
- References
- 165
- Citations by year
- 2026: 109 · 2025: 135 · 2024: 106 · 2023: 81 · 2022: 79 · 2021: 36
- FWCI
- 4.22
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- The Plant Journal (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (GM060396)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Stress Responses and Tolerance
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Seed Germination and Physiology
- Physical Sciences › Environmental Science › Global and Planetary Change › Plant Water Relations and Carbon Dynamics
- Keywords
- abscisic acid, stomatal closure, abscisic acid signaling, PYR/PYL/RCAR receptors, PP2C protein phosphatase, SnRK2 protein kinases, ABA receptors, CO2 signaling, vapor pressure deficit, stomatal conductance, drought tolerance, water use efficiency, plant hormone interaction
- MeSH terms
- Abscisic Acid, Plant Growth Regulators, Plants, Signal Transduction, Plant Stomata
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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