CoChat
Sign Up
Cited by 141

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Transverse distribution of plasma membrane bilayer cholesterol: Picking sides

Steck, Theodore L., Lange, Yvonne·2018·Traffic
DOI 10.1111/tra.12586
Open this paper in CoChat — free account

Abstract

The transverse asymmetry (sidedness) of phospholipids in plasma membrane bilayers is well characterized, distinctive, actively maintained and functionally important. In contrast, numerous studies using a variety of techniques have concluded that plasma membrane bilayer cholesterol is either mostly in the outer leaflet or the inner leaflet or is fairly evenly distributed. Sterols might simply partition according to their differing affinities for the asymmetrically disposed phospholipids, but some studies have proposed that it is actively transported to the outer leaflet. Other work suggests that the sterol is enriched in the inner leaflet, driven by either positive interactions with the phosphatidylethanolamine on that side or by its exclusion from the outer leaflet by the long chain sphingomyelin molecules therein. This uncertainty raises three questions: is plasma membrane cholesterol sidedness fixed in a given cell or cell type; is it generally the same among mammalian species; and does it serve specific physiological functions? This review grapples with these issues.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1111/tra.12586

Cites

2 of 2 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 132

  1. 10.3109/10409238309102790 · DOI
  2. 10.1016/0304-4157(85)90011-5 · DOI
  3. 10.1016/j.ceb.2010.05.004 · DOI · Paper page
  4. 10.1016/j.chemphyslip.2016.04.001 · DOI
  5. 10.1016/S0021-9258(19)84918-9 · DOI
  6. 10.1073/pnas.0307332101 · DOI
  7. 10.1016/j.ab.2009.07.027 · DOI
  8. 10.1073/pnas.1309273110 · DOI · Paper page
  9. 10.1038/nrm2330 · DOI · Paper page
  10. 10.1016/j.ceb.2013.03.005 · DOI
  11. 10.1016/j.plipres.2016.02.001 · DOI
  12. 10.1146/annurev.bi.48.070179.000403 · DOI
  13. 10.1042/bj2940001 · DOI
  14. 10.1016/j.chemphyslip.2015.07.012 · DOI
  15. 10.1016/j.bpj.2016.06.036 · DOI
  16. 10.1242/jcs.163105 · DOI
  17. 10.1016/j.chemphyslip.2015.08.009 · DOI
  18. 10.1016/j.febslet.2009.12.049 · DOI
  19. 10.1152/physrev.00020.2015 · DOI
  20. 10.1007/s12572-015-0155-9 · DOI
  21. 10.1007/s00018-005-4527-3 · DOI
  22. 10.1021/bi400862q · DOI · Paper page
  23. 10.1016/S0006-3495(90)82444-9 · DOI
  24. 10.1017/S0033583500003735 · DOI
  25. 10.1146/annurev.biophys.32.110601.141704 · DOI
  26. 10.1016/j.bbamcr.2005.06.010 · DOI
  27. 10.1021/jp3032868 · DOI
  28. 10.1007/978-1-59745-513-8 · DOI
  29. 10.1016/j.bbamem.2008.08.022 · DOI
  30. 10.1016/S0006-3495(02)75497-0 · DOI
  31. 10.1016/j.chemphyslip.2016.04.006 · DOI
  32. 10.1016/j.chemphyslip.2016.02.003 · DOI
  33. 10.1016/S0006-3495(02)73972-6 · DOI
  34. 10.1097/00041433-200306000-00006 · DOI · Paper page
  35. 10.1529/biophysj.107.122465 · DOI
  36. 10.1021/ja903529f · DOI
  37. 10.1016/j.bpj.2009.09.025 · DOI
  38. 10.1021/jp108166k · DOI
  39. 10.1021/ja507832e · DOI
  40. 10.1007/978-1-4939-1752-5_20 · DOI
  41. 10.1016/j.chemphyslip.2015.12.002 · DOI
  42. 10.1021/bi800123b · DOI
  43. 10.1016/S0006-3495(02)75340-X · DOI
  44. 10.1016/0005-2736(77)90350-9 · DOI
  45. 10.1016/0005-2736(79)90074-9 · DOI
  46. 10.1016/j.bpj.2014.10.012 · DOI
  47. 10.1242/jcs.164715 · DOI
  48. 10.1016/j.celrep.2018.06.104 · DOI
  49. 10.1073/pnas.162366399 · DOI
  50. 10.1038/nchembio.2268 · DOI · Paper page
  51. 10.1007/978-90-481-8622-8_1 · DOI
  52. 10.1083/jcb.62.1.1 · DOI
  53. 10.1073/pnas.73.1.173 · DOI
  54. 10.1083/jcb.93.1.155 · DOI
  55. 10.1007/978-94-017-8881-6_5 · DOI
  56. 10.1016/j.plipres.2008.03.001 · DOI
  57. 10.7554/eLife.23355 · DOI
  58. 10.1021/bi9002309 · DOI
  59. 10.1074/jbc.M110.148254 · DOI · Paper page
  60. 10.1016/j.bpj.2013.08.042 · DOI
  61. 10.1128/MCB.06113-11 · DOI
  62. 10.1021/bi3003132 · DOI
  63. 10.3390/toxins8030067 · DOI
  64. 10.1021/bi9828324 · DOI
  65. 10.1194/jlr.M500511-JLR200 · DOI
  66. 10.1016/j.febslet.2010.04.036 · DOI
  67. 10.1074/jbc.R114.583658 · DOI
  68. 10.1194/jlr.R082313 · DOI
  69. 10.1016/0003-9861(68)90008-8 · DOI
  70. 10.1091/mbc.E14-09-1347 · DOI
  71. 10.1074/jbc.M116.774471 · DOI
  72. 10.1007/s11745-008-3194-1 · DOI
  73. 10.1111/tra.12545 · DOI
  74. 10.1111/j.1432-1033.1982.tb06488.x · DOI
  75. 10.1016/0005-2736(91)90185-B · DOI
  76. 10.1016/0014-5793(88)80824-X · DOI
  77. 10.1016/0005-2736(88)90460-9 · DOI
  78. 10.1016/0005-2736(90)90103-U · DOI
  79. 10.1111/j.1471-4159.2010.07017.x · DOI
  80. 10.1016/j.bpj.2013.06.046 · DOI
  81. 10.1091/mbc.e08-07-0785 · DOI
  82. 10.1016/0005-2736(94)00311-C · DOI
  83. 10.1016/S0006-3495(98)77632-5 · DOI · Paper page
  84. 10.1016/j.steroids.2010.11.001 · DOI
  85. 10.1016/j.chemphyslip.2011.01.004 · DOI
  86. 10.1091/mbc.E16-07-0499 · DOI
  87. 10.1016/S0006-3495(97)78196-7 · DOI
  88. 10.1111/j.1600-0854.2005.00285.x · DOI
  89. 10.1021/bi0201670 · DOI
  90. 10.1074/jbc.M303567200 · DOI
  91. 10.1529/biophysj.105.072801 · DOI
  92. 10.1529/biophysj.105.067652 · DOI
  93. 10.1016/j.bpj.2009.12.4279 · DOI
  94. 10.1016/j.bbamem.2012.03.009 · DOI
  95. Brasaemle DL, 1988, Transbilayer movement of cholesterol in the human erythrocyte membrane, J Lipid Res, 29, 481, 10.1016/S0022-2275(20)38521-7 · DOI
  96. Lange Y, 1981, The rate of transmembrane movement of cholesterol in the human‐erythrocyte, J Biol Chem, 256, 5321, 10.1016/S0021-9258(19)69200-8 · DOI
  97. 10.1016/0005-2736(84)90053-1 · DOI
  98. 10.1016/0005-2736(77)90335-2 · DOI
  99. 10.1021/bi951846w · DOI
  100. 10.1016/j.cell.2015.03.048 · DOI
  101. 10.1016/j.bbamem.2015.12.003 · DOI
  102. 10.1016/0005-2736(83)90160-8 · DOI
  103. 10.1016/j.bbalip.2013.04.011 · DOI
  104. Dodge JT, 1967, Composition of phospholipids and of phospholipid fatty acids and aldehydes in human red cells, J Lipid Res, 8, 667, 10.1016/S0022-2275(20)38890-8 · DOI
  105. 10.1016/0005-2760(67)90152-X · DOI
  106. 10.1073/pnas.73.2.391 · DOI
  107. 10.1073/pnas.74.4.1538 · DOI
  108. 10.1016/0005-2736(78)90396-6 · DOI
  109. 10.1073/pnas.77.4.2255 · DOI
  110. 10.1016/j.bpj.2011.06.014 · DOI
  111. 10.1194/jlr.M077909 · DOI
  112. 10.1074/jbc.271.27.16026 · DOI
  113. 10.1007/s00249-012-0863-z · DOI
  114. 10.1021/acs.jpclett.6b02123 · DOI
  115. 10.1007/s10895-015-1589-y · DOI
  116. 10.1111/tra.12545 · DOI
  117. Blau L, 1978, Cholesterol distribution between the two halves of the lipid bilayer of human erythrocyte ghost membranes, J Biol Chem, 253, 8366, 10.1016/S0021-9258(17)34300-4 · DOI
  118. 10.1021/bi00512a009 · DOI
  119. 10.1016/S0006-3495(74)85959-X · DOI
  120. 10.1073/pnas.71.11.4457 · DOI
  121. 10.1016/0022-5193(78)90358-2 · DOI
  122. 10.1016/S0006-3495(92)81841-6 · DOI
  123. Lange Y, 1980, The effect of cholesterol and other intercalated Amphipaths on the contour and stability of the isolated red‐cell membrane, J Biol Chem, 255, 9331, 10.1016/S0021-9258(19)70566-3 · DOI
  124. Lange Y, 1982, Interaction of cholesterol and lysophosphatidylcholine in determining red cell shape, J Lipid Res, 23, 1121, 10.1016/S0022-2275(20)38048-2 · DOI
  125. 10.1002/jss.400090315 · DOI
  126. 10.1073/pnas.0408215102 · DOI
  127. 10.1016/0009-3084(94)90177-5 · DOI
  128. 10.1074/jbc.C114.570267 · DOI
  129. 10.1172/JCI104810 · DOI
  130. Das A, 2014, Three pools of plasma membrane cholesterol and their relation to cholesterol homeostasis, Elife, e02882, 10.7554/eLife.02882 · DOI · Paper page
  131. 10.1016/0005-2736(92)90190-W · DOI
  132. 10.1016/j.anaerobe.2003.09.003 · DOI

Cited by

Sorted by citations

Metadata

Authors
Steck, T. L., & Lange, Y.
Venue
Traffic
Publisher
Wiley
Published
2018-07-08
Volume
19
Issue
10
Pages
750-760
ISSN
  • 1398-9219
  • 1600-0854
DOI
10.1111/tra.12586
Cited by
141
References
2
Language
en
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review