The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Theta‐burst repetitive transcranial magnetic stimulation suppresses specific excitatory circuits in the human motor cortex
Abstract
In four conscious patients who had electrodes implanted in the cervical epidural space for the control of pain, we recorded corticospinal volleys evoked by single‐pulse transcranial magnetic stimulation (TMS) over the motor cortex before and after a 20 s period of continuous theta‐burst stimulation (cTBS). It has previously been reported that this form of repetitive TMS reduces the amplitude of motor‐evoked potentials (MEPs), with the maximum effect occurring at 5–10 min after the end of stimulation. The present results show that cTBS preferentially decreases the amplitude of the corticospinal I1 wave, with approximately the same time course. This is consistent with a cortical origin of the effect on the MEP. However, other protocols that lead to MEP suppression, such as short‐interval intracortical inhibition, are characterized by reduced excitability of late I waves (particularly I3), suggesting that cTBS suppresses MEPs through different mechanisms, such as long‐term depression in excitatory synaptic connections.
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Cites
Theta Burst Stimulation of the Human Motor Cortex
Huang, Y.-Z., Edwards, M. J., Rounis, E., Bhatia, K. P., & Rothwell, J. C. (2005) · Neuron · doi:10.1016/j.neuron.2004.12.033 · Cited by 4,158
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Self-citationDepression of motor cortex excitability by low-frequency transcranial magnetic stimulation
Chen, R., Classen, J., Gerloff, C., Celnik, P., Wassermann, E. M., Hallett, M., & Cohen, L. G. (1997) · Neurology · doi:10.1212/wnl.48.5.1398 · Cited by 2,128 · cited 4×
“…to produce effects on the excitability of the corticospinal system that outlast the period of stimulation for several minutes or even hours (Pascual-Leone et al. 1994, 1998; Chen et al. 1997; Tergau et al. 1997; Berardelli et al. 1998; Peinemann et al. 2000; Maeda et al. 2000; Huang et al. 2005).”
BackgroundInfluentialResponses to rapid-rate transcranial magnetic stimulation of the human motor cortex
Pascual-Leone, A., Valls-Solé, J., Wassermann, E. M., & Hallett, M. (1994) · Brain · doi:10.1093/brain/117.4.847 · Cited by 1,457
Study and Modulation of Human Cortical Excitability With Transcranial Magnetic Stimulation
Pascual-Leone, A., Tormos, J. M., Keenan, J., Tarazona, F., Cañete, C., & Catalá, M. D. (1998) · Journal of Clinical Neurophysiology · doi:10.1097/00004691-199807000-00005 · Cited by 780
Maeda, F., Keenan, J. P., Tormos, J. M., Topka, H., & Pascual-Leone, A. (2000) · Experimental Brain Research · doi:10.1007/s002210000432 · Cited by 651
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Self-citationThe physiological basis of transcranial motor cortex stimulation in conscious humans
Di Lazzaro, V, Oliviero, A., Pilato, F., Saturno, E., Dileone, M., Mazzone, P., Insola, A., Tonali, P. A., & Rothwell, J. C. (2004) · Clinical Neurophysiology · doi:10.1016/j.clinph.2003.10.009 · Cited by 584
Self-citationDopamine: a potential substrate for synaptic plasticity and memory mechanisms
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Facilitation of muscle evoked responses after repetitive cortical stimulation in man
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Self-citation
Research works printed but not linked: 1
- Tergau F, 1997, Effects of repetitive transcranial magnetic stimulation (rTMS) on cortico‐spinal and cortico‐cortical excitability, Neurology, 48, A107
Cited by
Lefaucheur, J.-P., André-Obadia, N., Antal, A., Ayache, S. S., Baeken, C., Benninger, D. H., Cantello, R. M., Cincotta, M., de Carvalho, M., De Ridder, D., et al. (2014) · Clinical Neurophysiology · doi:10.1016/j.clinph.2014.05.021 · Cited by 2,119
Self-citationPhysiology of repetitive transcranial magnetic stimulation of the human brain
Hoogendam, J. M., Ramakers, G. M. J., & Di Lazzaro, V. (2010) · Brain Stimulation · doi:10.1016/j.brs.2009.10.005 · Cited by 669
Self-citationConsensus: Motor cortex plasticity protocols
Ziemann, U., Paulus, W., Nitsche, M. A., Pascual-Leone, A., Byblow, W. D., Berardelli, A., Siebner, H. R., Classen, J., Cohen, L. G., & Rothwell, J. C. (2008) · Brain Stimulation · doi:10.1016/j.brs.2008.06.006 · Cited by 639
Self-citationTen years of theta burst stimulation in humans: Established knowledge, unknowns and prospects
Suppa, A., Huang, Y.-Z., Funke, K., Ridding, M. C., Cheeran, B., Di Lazzaro, V., Ziemann, U., & Rothwell, J. C. (2016) · Brain Stimulation · doi:10.1016/j.brs.2016.01.006 · Cited by 609
“The cTBS protocol suppresses the I1 wave, whilst later I waves and the D-wave are much less affected (Figure 2) [Di Lazzaro et al., 2005; Di Lazzaro and Rothwell, 2014; 11,14].”
Self-citationGeorge, M. S., & Aston-Jones, G. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.87 · Cited by 401
Metadata
- Authors
- Di Lazzaro, V., Pilato, F., Saturno, E., Oliviero, A., Dileone, M., Mazzone, P., Insola, A., Tonali, P. A., Ranieri, F., Huang, Y. Z., & Rothwell, J. C.
- Venue
- The Journal of Physiology
- Publisher
- Wiley
- Published
- 2005-06-15
- Volume
- 565
- Issue
- 3
- Pages
- 945-950
- ISSN
- 0022-3751 (ISSN-L)
- 1469-7793
- OpenAlex
- W2134261171
- Cited by
- 423
- References
- 23
- FWCI
- 7.68
- Type
- journal article
- Language
- en
- Open access
- closed
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- Di Lazzaro, V., Pilato, F., Saturno, E., Oliviero, A., Dileone, M., Mazzone, P., Insola, A., Tonali, P. A., Ranieri, F., Huang, Y. Z., & Rothwell, J. C. (2005). Theta‐burst repetitive transcranial magnetic stimulation suppresses specific excitatory circuits in the human motor cortex. The Journal of Physiology. https://doi.org/10.1113/jphysiol.2005.087288
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