Prototype laser-activated shape memory polymer foam device for embolic treatment of aneurysms
Open accessAbstract
Conventional embolization of cerebral aneurysms using detachable coils is time-consuming and often requires retreatment. These drawbacks have prompted the development of new methods of aneurysm occlusion. We present the fabrication and laser deployment of a shape memory (SMP) polymer expanding foam device. Data acquired in an in vitro basilar aneurysm model with and without flow showed successful treatment, with the flow rate affecting foam expansion and the temperature at the aneurysm wall.
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- Authors
- Maitland, D. J., Small, W., Ortega, J. M., Buckley, P. R., Rodriguez, J., Hartman, J., & Wilson, T. S.
- Affiliations
- Lawrence Livermore National Laboratory (US)
- Lawrence Livermore National Lab.
- Kaiser Permanente (US)
- Venue
- Journal of Biomedical Optics
- Publisher
- SPIE-Intl Soc Optical Eng
- Published
- 2007-05-01
- Volume
- 12
- Issue
- 03
- Pages
- 1-3
- ISSN
- 1083-3668 (ISSN-L)
- 1560-2281
- OpenAlex
- W2141325516
- Cited by
- 107
- References
- 14
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 1 · 2023: 4 · 2022: 1 · 2021: 5 · 2020: 7 · 2019: 4 · 2018: 1 · 2017: 11 · 2016: 11 · 2015: 7 · 2014: 5 · 2013: 9 · 2012: 11
- FWCI
- 3.46
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Biomedical Optics (publishedVersion)
- PubMed (publishedVersion)
- OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) (submittedVersion)
- University of North Texas Digital Library (University of North Texas) (submittedVersion)
- Funders
- U.S. Department of Energy (W-7405, W‐7405‐ENG‐48)
- National Institutes of Health (W-7405-ENG-48)
- National Institute of Biomedical Imaging and Bioengineering (R01EB000462)
- Lawrence Livermore National Laboratory
- Topics
- Health Sciences › Medicine › Neurology › Intracranial Aneurysms: Treatment and Complications
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Aortic aneurysm repair treatments
- Health Sciences › Medicine › Genetics › Vascular Anomalies and Treatments
- Keywords
- shape memory polymer foam, cerebral aneurysm embolization, aneurysm occlusion, basilar artery aneurysm, foam expansion, detachable coils, in vitro aneurysm model
- MeSH terms
- Aneurysm, Animals, Biocompatible Materials, Embolization, Therapeutic, Gases, Humans, Lasers, Materials Testing, Pilot Projects, Polymers
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