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Prolonged Vitamin C Supplementation and Recovery from Demanding Exercise
Abstract
The aim of the present study was to investigate whether 2 weeks of vitamin C supplementation affects recovery from an unaccustomed bout of exercise. Sixteen male subjects were allocated to either a placebo (P; n = 8) or vitamin C group (VC; n = 8). The VC group consumed 200 mg of ascorbic acid twice a day, whereas the P group consumed identical capsules containing 200 mg of lactose. Subjects performed a prolonged (90-min) intermittent shuttle-running test 14 days after supplementation began. Post-exercise serum creatine kinase activities and myoglobin concentrations were unaffected by supplementation. However, vitamin C supplementation had modest beneficial effects on muscle soreness, muscle function, and plasma concentrations of malondialdehyde. Furthermore, although plasma interleukin-6 increased immediately after exercise in both groups, values in the VC group were lower than in the P group 2 hours after exercise (p < .05). These results suggest that prolonged vitamin C supplementation has some modest beneficial effects on recovery from unaccustomed exercise.
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“Although vitamins C and E are potent antioxidants, there is no conclusive evidence demonstrating a positive effect on physical performance in individuals supplemented with these two vitamins [39,40].”
From Use of Nutritional Strategies, Bioactive Compounds, and Dietary Supplements in Young Athletes: From Evidence to Potential Risks—A Narrative Review (2025) · cites this paper as [39]
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Citations
Cited by
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Fischer, C. P., Hiscock, N. J., Penkowa, M., Basu, S., Vessby, B., Kallner, A., Sjöberg, L., & Pedersen, B. K. (2004) · The Journal of Physiology · doi:10.1113/jphysiol.2004.066779 · Cited by 293
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Levers, K., Dalton, R., Galvan, E., O’Connor, A., Goodenough, C., Simbo, S., Mertens-Talcott, S. U., Rasmussen, C., Greenwood, M., Riechman, S., et al. (2016) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-016-0133-z · Cited by 111
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Metadata
- Authors
- Thompson, D., Williams, C., McGregor, S. J., Nicholas, C. W., McArdle, F., Jackson, M. J., & Powell, J. R.
- Venue
- International Journal of Sport Nutrition and Exercise Metabolism
- Publisher
- Human Kinetics
- Published
- 2001-12
- Volume
- 11
- Issue
- 4
- Pages
- 466-481
- ISSN
- 1526-484X
- 1543-2742
- Cited by
- 92
- References
- 0
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