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Vargas‐Medrano, J., Castrejón-Téllez, V., Plenge‐Tellechea, F., Ramirez, I. R., & Miranda, M. (2011) · Neurochemistry International · doi:10.1016/j.neuint.2011.08.006 · Cited by 22 · see citing works

PKC phosphorylates residues in the N-terminal of the DA transporter to regulate amphetamine-induced DA efflux

Wang, Q., Bubula, N., Brown, J., Wang, Y., Kondev, V., & Vezina, P. (2016) · Neuroscience Letters · doi:10.1016/j.neulet.2016.04.051 · Cited by 20 · see citing works

Tamoxifen and amphetamine abuse: Are there therapeutic possibilities?

Mikelman, S. R., Mardirossian, N., & Gnegy, M. E. (2016) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2016.08.004 · Cited by 20 · see citing works

Neuropeptide Y Y5 receptor antagonism causes faster extinction and attenuates reinstatement in cocaine-induced place preference

Sørensen, G., Wörtwein, G., Fink‐Jensen, A., & Woldbye, D. P. D. (2013) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2013.02.010 · Cited by 19 · see citing works

Protein kinase C isozymes as regulators of sensitivity to and self-administration of drugs of abuse-studies with genetically modified mice

Olive, M. F., & Newton, P. M. (2010) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e32833d8bb7 · Cited by 19 · see citing works

Presynaptic Gq-coupled receptors drive biphasic dopamine transporter trafficking that modulates dopamine clearance and motor function

Kearney, P. J., Bolden, N. C., Kahuno, E. W., Conklin, T. L., Martin, G. E., Lübec, G., & Melikian, H. E. (2023) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2023.102900 · Cited by 16 · see citing works

PKC-Dependent GlyT1 Ubiquitination Occurs Independent of Phosphorylation: Inespecificity in Lysine Selection for Ubiquitination

Barrera, S. P., Castrejón-Téllez, V., Trinidad, M., Robles‐Escajeda, E., Vargas‐Medrano, J., Varela-Ramı́rez, A., & Miranda, M. (2015) · PLoS ONE · doi:10.1371/journal.pone.0138897 · Cited by 16 · see citing works

Involvement of threonine 258 and serine 259 motif in amphetamine‐induced norepinephrine transporter endocytosis

Annamalai, B., Mannangatti, P., Arapulisamy, O., Ramamoorthy, S., & Jayanthi, L. D. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.06898.x · Cited by 16 · see citing works

Phosphorylation of the Amino Terminus of the Dopamine Transporter: Regulatory Mechanisms and Implications for Amphetamine Action

Karam, C. S., & Javitch, J. A. (2017) · Advances in pharmacology · doi:10.1016/bs.apha.2017.09.002 · Cited by 15 · see citing works

Cyclin-Dependent Kinase 5 Inhibitors: Inhibition of Dopamine Transporter Activity

Price, D. A., Sorkin, A. D., & Zahniser, N. R. (2009) · Molecular Pharmacology · doi:10.1124/mol.109.056978 · Cited by 14 · see citing works

Ruboxistaurin Reduces Cocaine-Stimulated Increases in Extracellular Dopamine by Modifying Dopamine-Autoreceptor Activity

Zestos, A. G., Carpenter, C., Kim, Y., Low, M. J., Kennedy, R. T., & Gnegy, M. E. (2018) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.8b00259 · Cited by 14 · see citing works

Dopamine and the phosphorylated dopamine transporter are increased in the diacylglycerol kinase η‐knockout mouse brain

Asami, M., Suzuki, Y., & Sakane, F. (2021) · FEBS Letters · doi:10.1002/1873-3468.14059 · Cited by 10 · see citing works

Prolonged ethanol exposure modulates constitutive internalization and recycling of 5‐HT1A receptors

Wang, S., Liu, H., Roberts, J. B., Wiley, A. P., Marayati, B. F., Adams, K. L., Luessen, D. J., Eldeeb, K., Sun, H., Zhang, K., et al. (2021) · Journal of Neurochemistry · doi:10.1111/jnc.15564 · Cited by 9 · see citing works

Atorvastatin differentially regulates the interactions of cocaine and amphetamine with dopamine transporters

Wang, S., Neel, A. I., Adams, K. L., Sun, H., Jones, S. R., Howlett, A. C., & Chen, R. (2022) · Neuropharmacology · doi:10.1016/j.neuropharm.2022.109387 · Cited by 8 · see citing works

PKCβ co-localizes with the dopamine transporter in mesencephalic neurons

O’Malley, H. A., Park, Y., Isom, L. L., & Gnegy, M. E. (2010) · Neuroscience Letters · doi:10.1016/j.neulet.2010.05.091 · Cited by 8 · see citing works

Interference of norepinephrine transporter trafficking motif attenuates amphetamine-induced locomotor hyperactivity and conditioned place preference

Mannangatti, P., Ramamoorthy, S., & Jayanthi, L. D. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.10.005 · Cited by 8 · see citing works

Phospho-specific antibodies targeting the amino terminus of the human dopamine transporter

Karam, C. S., Sen, N., & Javitch, J. (2017) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2017.05.003 · Cited by 7 · see citing works

A mathematical model for the role of dopamine-D2 self-regulation in the production of ultradian rhythms

Zhang, A. Q., Ralph, M. R., & Stinchcombe, A. R. (2024) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1012082 · Cited by 5 · see citing works

Amphetamine Induces Sex-Dependent Loss of the Striatal Dopamine Transporter in Sensitized Mice

Bagalkot, T. R., & Sorkin, A. D. (2023) · eNeuro · doi:10.1523/eneuro.0491-23.2023 · Cited by 5 · see citing works

An acute, epitope‐specific modification in the dopamine transporter associated with methamphetamine‐induced neurotoxicity

Fricks-Gleason, A. N., German, C. L., Hoonakker, A. J., Friend, D. M., Ganesh, K., Carver, A. S., Hanson, G., Fleckenstein, A., & Keefe, K. (2016) · Synapse · doi:10.1002/syn.21891 · Cited by 6 · see citing works

Identification by proximity labeling of novel lipidic and proteinaceous potential partners of the dopamine transporter

Piniella, D., Martínez‐Blanco, E., Bartolomé‐Martín, D., Sanz-Martos, A. B., & Zafra, F. (2021) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-021-03998-1 · Cited by 5 · see citing works

Regulation of Dopamine Transporter Surface Expression

Besada, C., & Mortensen, O. V. (2025) · Advances in neurobiology · doi:10.1007/978-3-031-96364-3_4 · Cited by 4 · see citing works

Lack of Cdk5 activity is involved on Dopamine Transporter expression and function: Evidences from an animal model of Attention-Deficit Hyperactivity Disorder

Fernández, G., Krapacher, F. A., Ferreras, S., Quassollo, G., Mari, M. M., Pisano, M. V., Montemerlo, A., Rubianes, M. D., Bregonzio, C., Arias, C., et al. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113866 · Cited by 4 · see citing works

Iron chelation down-regulates dopamine transporter expression by decreasing mRNA stability and increasing endocytosis in N2a cells

Hegde, N. V., Jensen, G. L., & Unger, E. L. (2010) · Experimental Cell Research · doi:10.1016/j.yexcr.2010.12.006 · Cited by 4 · see citing works

The protein kinase Cβ-selective inhibitor, enzastaurin, attenuates amphetamine-stimulated locomotor activity and self-administration behaviors in rats

Altshuler, R. D., Carpenter, C., Franke, T. J., Gnegy, M. E., & Jutkiewicz, E. M. (2019) · Psychopharmacology · doi:10.1007/s00213-019-05278-0 · Cited by 4 · see citing works

Optogenetically-induced multimerization of the dopamine transporter increases uptake and trafficking to the plasma membrane

Ingram, S., Rana, T., Manson, A. M., Yayah, F. M., Jackson, E. G. B., Anderson, C. D., Davids, B., & Goodwin, J. (2021) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2021.100787 · Cited by 2 · see citing works

Amphetamine-induced ERM Proteins Phosphorylation Is through PKCβ Activation in PC12 Cells

Jeong, H. J., Kim, J., & Jeon, S. (2011) · Korean Journal of Physiology and Pharmacology · doi:10.4196/kjpp.2011.15.4.245 · Cited by 3 · see citing works

Methcathinone decreases dopamine transporter function: Role of protein kinase C

Magee, C., Le, B. D., Siripathane, Y. H., Wilkins, D., Hanson, G., & Fleckenstein, A. (2021) · Journal of Neurochemistry · doi:10.1111/jnc.15483 · Cited by 3 · see citing works

G protein-coupled receptor signaling in VTA dopaminergic neurons bidirectionally regulates the acute locomotor response to amphetamine but does not affect behavioral sensitization

Runegaard, A. H., Dencker, D., Wörtwein, G., & Gether, U. (2019) · Neuropharmacology · doi:10.1016/j.neuropharm.2019.06.002 · Cited by 2 · see citing works

Cholesterol modulation of interactions between psychostimulants and dopamine transporters

Chen, R. (2023) · Advances in pharmacology · doi:10.1016/bs.apha.2023.09.004 · Cited by 2 · see citing works

Monoamine transporter ubiquitination and inward-open conformation synergistically maximize transporter endocytosis

Sorkina, T., Bagalkot, T. R., Cheng, M. H., Guthrie, D. A., Newman, A. H., Watkins, S. C., & Sorkin, A. D. (2024) · Science Advances · doi:10.1126/sciadv.adq9793 · Cited by 2 · see citing works

PKC inhibition decreases amphetamine-maintained responding under a progressive-ratio schedule of reinforcement.

Altshuler, R. D., Mac, R. C., Gnegy, M. E., & Jutkiewicz, E. M. (2020) · Experimental and Clinical Psychopharmacology · doi:10.1037/pha0000425 · Cited by 2 · see citing works

The Role of Insulin Signaling on Dopamine Transporter Trafficking

Speed, N. K. (2010) · Cited by 2 · see citing works

Towards an understanding of the psychostimulant action of amphetamine and cocaine

Weissensteiner, R., Steinkellner, T., Jurik, A., Bulling, S., Sandtner, W., Kudlacek, O., Freissmuth, M., Ecker, G. F., & Sitte, H. H. (2012) · Springer eBooks · doi:10.1007/978-3-211-99751-2_11 · Cited by 1 · see citing works

DIET-INDUCED OBESITY: DOPAMINERGIC AND BEHAVIORAL MECHANISMS AS OUTCOMES AND PREDICTORS

Narayanaswami, V. (2013) · UKnowledge (University of Kentucky) · Cited by 1 · see citing works

Neurokinin-1 Antagonism Distinguishes the Role of Norepinephrine Transporter from Dopamine Transporter in Mediating Amphetamine Behaviors

Mannangatti, P., Varman, D. R., Ramamoorthy, S., & Jayanthi, L. D. (2021) · Pharmacology · doi:10.1159/000518033 · Cited by 1 · see citing works

Endocytic down-regulation of the striatal dopamine transporter by amphetamine in sensitized mice in sex-dependent mannerPreprint

Bagalkot, T. R., & Sorkin, A. D. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.05.17.541165 · Cited by 1 · see citing works

Regulation of the D2-Like Dopamine Autoreceptor by the Dopamine Transporter.

Luderman, K. D. (2014) · Deep Blue (University of Michigan)

Regulation of dopamine transporter trafficking by substrates, Rabs, and SNAREs

Furman, C. A. (2009)

This month in APR

Lee, J. (2009) · Archives of Pharmacal Research · doi:10.1007/s12272-009-2199-5

ThePlasmaMembrane-AssociatedGTPaseRinInteracts withtheDopamineTransporterandIsRequiredforProtein KinaseC-RegulatedDopamineTransporterTrafficking

Navaroli, D. M., Stevens, Z., & Lifshitz, L. M. (2011)

PKC BETA AS A NEW THERAPY TARGET ON PREVENTION OF WEIGHT GAIN DURING LONG- TERM ATYPICAL ANTIPSYCHOTICS TREATMENT

Biomediche, S. (2014)

Paying attention to the details: rare genetic variation in the dopamine transporter and ADHD

Sakrikar, D. S. (2012)

Molecular Mediators of Acute and Chronic Itch in Mouse and Human Sensory Neurons

Valtcheva, M. V. (2018) · Open Scholarship Institutional Repository (Washington University in St. Louis) · doi:10.7936/k7vd6xw7

Synthesis and Characterization of the Selective, Reversible PKCβ Inhibitor (9S)-9-[(Dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione, Ruboxistaurin (LY333531)

Lewin, A. H., Brieaddy, L., Deschamps, J. R., Imler, G. H., Mascarella, S. W., Reddy, P. A., & Carroll, F. I. (2018) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.8b00196

Membrane partitioning by Flotillin-1 facilitates amphetamine-induced dopamine transporter activity

Fong, W. M. (2017) · doi:10.7916/d8qn6k9f

Development of a Semimechanistic Pharmacokinetic-Pharmacodynamic Model Describing Dextroamphetamine Exposure and Striatal Dopamine Response in Rats and Nonhuman Primates following a Single Dose of Dextroamphetamine

van Gaalen, M. M., Schlumbohm, C., Folgering, J. H. A., Adhikari, S., Bhattacharya, C. S., Steinbach, D., & Stratford, R. E. (2019) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.118.254508

Investigating the Role of Protein Kinase C Inhibitors in Amphetamine-Mediated Behaviors

Altshuler, R. D. (2019) · Deep Blue (University of Michigan)

Lack of Cdk5 activity is involved on Dopamine Transporter expression and function: Evidences from an animal model of Attention-Deficit Hyperactivity DisorderPreprint

Guillermo, F., Favio, K., Soledad, F., Gonzalo, Q., Mariel, M. M., Victoria, P. M., Antonella, M., Dolores, R. M., Claudia, B., Arias, C., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.03.19.436226

PKCβ ACTIVITY REGULATES DAT PLASMA MEMBRANE PRESENTATION

King, M. J. (2010)

Post-translational mechanisms in psychostimulant-induced neurotransmitter efflux

Vaughan, R. A., Henry, L. K., Foster, J. D., & Brown, C. R. (2024) · Advances in pharmacology · doi:10.1016/bs.apha.2023.10.003

Life-time levonorgestrel exposure causes intergenerational alterations of the thyroid-catecholaminergic–GABAergic functional network in zebrafish (Danio rerio)

Hu, X., Cai, Q., Wu, J., Ye, M., Yang, J., Huang, H., Liang, W., Zhang, Y., Shi, R., Liu, Y., et al. (2026) · Environmental Research · doi:10.1016/j.envres.2026.124496

Dynamic Regulation at the Neuronal Plasma Membrane: Novel Endocytic Mechanisms Control Anesthetic-Activated Potassium Channels and Amphetamine-Sensitive Dopamine Transporters: A Dissertation

Gabriel, L. R. (2013) · eScholarship@UMassChan · doi:10.13028/m22k5h

Conduction states of the human dopamine transporter

Cameron, K. N. (2015) · VCU Scholars Compass (Virginia Commonwealth University) · doi:10.25772/eczm-xs03

Molecular Mechanisms of Endocytosis: Trafficking and Functional Requirements for the Transferrin Receptor, Small Interfering RNAs and Dopamine Transporter: A Dissertation

Navaroli, D. M. (2012) · The Journal of the American Medical Association (JAMA) Network (American Medical Association) · doi:10.13028/5ajq-y522

Protein Kinase C Is a Critical Regulator of Dopamine Transporter Trafficking and Regulates the Behavioral Response to Amphetamine in Mice”. Pharmacology 328

Chen, R., Furman, C. A., Zhang, M., Kim, M. N., Gereau, R. W., Leitges, M., & Gnegy, M. E. (2009)

Regulation of Amphetamine-stimulated Dopamine Efflux by Protein Kinase C β

Johnson, L. A., Guptaroy, B., Lund, D., Shamban, S., & Gnegy, M. E. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m413887200 · Cited by 135 · see citing works

Authors and author addresses:

Chen, R., Furman, C. A., Zhang, M., Kim, M. N., Gereau, R. W., Leitges, M., Gnegy, M. E., At, A., Response, A., Margaret, D., et al. (2016)

THE PROTEIN KINASE Cβ INHIBITOR, ENZASTAURIN, DECREASES AMPHETAMINE‐MEDIATED BEHAVIORS IN RATS

Altshuler, R. D., Gnegy, M. E., & Jutkiewicz, E. M. (2016) · The FASEB Journal · doi:10.1096/fasebj.30.1_supplement.1183.8 · Cited by 1 · see citing works

Protein kinase C and dopamine transport—1. Effects of amphetamine in vivo

Giambalvo, C. T. (1992) · Neuropharmacology · doi:10.1016/0028-3908(92)90048-t · Cited by 64 · see citing works