Selective Inhibition of Casein Kinase 1ϵ Minimally Alters Circadian Clock Period

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Repositioning of Etravirine as a Potential CK1ε Inhibitor by Virtual Screening

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Novel Prognostic Markers and Therapeutic Targets for Glioblastoma

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Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of

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The circadian clock gene bmal1 is necessary for co-ordinated circatidal rhythms in the marine isopod Eurydice pulchra (Leach)Preprint

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GVB+ neurons are resilient to tau-induced protein synthesis impairmentPreprint

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Inhibition of Casein Kinase 1δ as a Novel Therapeutic Strategy for Amyotrophic Lateral Sclerosis: A Theoretical Study

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Cocaine‐Induced Changes in the BRD 4 Interactome Identifies Casein Kinase 1 Epsilon as a Therapeutic Target

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Uso de supercómputo para el descubrimiento de fármacos: un caso de estudio sobre CK1ε

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Chemical regulation of circadian rhythms through inhibition of casein kinase Iδ and α

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BindingDB Entry 50022646: Silencing c-Myc translation as a therapeutic strategy through targeting PI3Kδ and CK1ε in hematological malignancies.

BindingDB (2025) · UC San Diego · doi:10.7270/q2ks6x8v

BindingDB Entry 50040761: Structural basis for the potent and selective inhibition of casein kinase 1 epsilon.

BindingDB (2013) · UC San Diego · doi:10.7270/q2ff3tgg

BindingDB Entry 50043328: Ligand-protein interactions of selective casein kinase 1d inhibitors.

BindingDB (2014) · UC San Diego · doi:10.7270/q2125v36

BindingDB Entry 50034557: Structural basis for the interaction between casein kinase 1 delta and a potent and selective inhibitor.

BindingDB (2012) · UC San Diego · doi:10.7270/q2x63nfw

BindingDB Entry 50045807: Synthesis and identification of unprecedented selective inhibitors of CK1e.

BindingDB (2016) · UC San Diego · doi:10.7270/q2hd7xbq

BindingDB Entry 50002158: Development of dual casein kinase 1δ/1ε (CK1δ/ε) inhibitors for treatment of breast cancer.

BindingDB (2020) · UC San Diego · doi:10.7270/q2rr21tz

BindingDB Entry 50019649: Structure-Based Optimization of Selective and Brain Penetrant CK1δ Inhibitors for the Treatment of Circadian Disruptions.

BindingDB (2024) · UC San Diego · doi:10.7270/q2qr52h5

BindingDB Entry 50007386: Small molecule modulators targeting protein kinase CK1 and CK2.

BindingDB (2021) · UC San Diego · doi:10.7270/q29k4fjb

BindingDB Entry 50045117: Synthesis and structure-activity relationships of 4-fluorophenyl-imidazole p38a MAPK, CK1d and JAK2 kinase inhibitors.

BindingDB (2016) · UC San Diego · doi:10.7270/q2d50pkz

BindingDB Entry 7363: Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1.

BindingDB (2016) · UC San Diego · doi:10.7270/q2gq6wjd

BindingDB Entry 50022927: Development and Discovery of a Selective Degrader of Casein Kinases 1 δ/ε.

BindingDB (2026) · UC San Diego · doi:10.7270/q2vq37jt

BindingDB Entry 50048252: Non-kinase targets of protein kinase inhibitors.

BindingDB (2018) · UC San Diego · doi:10.7270/q2125vnc

BindingDB Entry 50042090: Discovery of N6-phenyl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine derivatives as novel CK1 inhibitors using common-feature pharmacophore model based virtual screening and hit-to-lead optimization.

BindingDB (2013) · UC San Diego · doi:10.7270/q2fj2j2f

Selective Inhibition of Casein Kinase 1 Minimally Alters Circadian Clock Period□S

Walton, K. M., Fisher, K., Rubitski, D. M., Marconi, M., Meng, Q., Adams, J., Bass, M., Ch, R., Butler, T., Griffor, M., et al. (2009)

Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes

Meng, Q., Maywood, E. S., Bechtold, D. A., Lu, W., Li, J., Gibbs, J. E., Dupré, S. M., Chesham, J. E., Rajamohan, F., Knafels, J. D., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1005101107 · Cited by 253

An Inhibitor of Casein Kinase Iϵ Induces Phase Delays in Circadian Rhythms under Free-Running and Entrained Conditions

Badura, L., Swanson, T., Adamowicz, W., Adams, J., Cianfrogna, J., Fisher, K., Holland, J., Kleiman, R., Nelson, F., Reynolds, L., et al. (2007) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.107.122846 · Cited by 176

Chronic treatment with a selective inhibitor of casein kinase I δ/ε yields cumulative phase delays in circadian rhythms

Sprouse, J. S., Reynolds, L. S., Kleiman, R. J., Tate, B. A., Swanson, T. A., & Pickard, G. E. (2010) · Psychopharmacology · doi:10.1007/s00213-010-1860-5 · Cited by 30

Casein Kinase 1 Delta Regulates the Pace of the Mammalian Circadian Clock

Etchegaray, J., Machida, K., Noton, E., Constance, C. M., Dallmann, R., Napoli, M. N. D., DeBruyne, J. P., Lambert, C. M., Yu, E. A., Reppert, S. M., et al. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.00338-09 · Cited by 244