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Hwang, J.-H. L., Perloff, O. S., Gaus, S. E., Benitez, C., Alquezar, C., Cosme, C. Q., Nana, A. L., Vatsavayai, S. C., Ramos, E. M., Geschwind, D. H., et al. (2023) · Acta Neuropathologica · doi:10.1007/s00401-022-02521-5 · Cited by 15 · see citing works

HMGCS2-Induced Autophagic Degradation of Tau Involves Ketone Body and ANKRD24

Hu, L.-T., Xie, X.-Y., Zhou, G.-F., Wen, Q.-X., Song, L., Luo, B., Deng, X.-J., Pan, Q.-L., & Chen, G.-J. (2023) · Journal of Alzheimer's Disease · doi:10.3233/jad-220640 · Cited by 14 · see citing works

An mTOR-independent Macroautophagy Activator Ameliorates Tauopathy and Prionopathy Neurodegeneration PhenotypesPreprint

Yoon, L., Botham, R. C., Verhelle, A., Wu, Y., Cole, C. M., Tan, E. P., Massey, L. A., Sanz-Martinez, P., Chou, C., Xu, J., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.09.29.509997 · Cited by 11 · see citing works

Microtubule Cytoskeletal Network Alterations in a Transgenic Model of Tuberous Sclerosis Complex: Relevance to Autism Spectrum Disorders

Gąssowska-Dobrowolska, M., Czapski, G. A., Cieślik, M., Zajdel, K., Frontczak-Baniewicz, M., Babiec, L., & Adamczyk, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087303 · Cited by 10 · see citing works

Shared mechanisms of neural circuit disruption in tuberous sclerosis across lifespan: Bridging neurodevelopmental and neurodegenerative pathology

Litwa, K. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.997461 · Cited by 10 · see citing works

The Deficits of Insulin Signal in Alzheimer’s Disease and the Mechanisms of Vanadium Compounds in Curing AD

Yao, J., He, Z., You, G., Liu, Q., & Li, N. (2023) · Current Issues in Molecular Biology · doi:10.3390/cimb45080402 · Cited by 9 · see citing works

Selective autophagy: a therapeutic target for healthy aging?

Manastireanu, D. M., Salazar, N., Bejarano, E., & Nieto-Torres, J. L. (2024) · Aging Advances · doi:10.4103/agingadv.agingadv-d-24-00002 · Cited by 7 · see citing works

Advancement of disease-modifying therapy of Alzheimer’s disease: from the perspective of new revised criteria for diagnosis and staging of Alzheimer’s disease

Wu, J., Geng, C.-F., Liu, L., & Tang, Y. (2025) · Medicine Plus · doi:10.1016/j.medp.2025.100112 · Cited by 6 · see citing works

The mTOR pathway genes MTOR, Rheb, Depdc5, Pten, and Tsc1 have convergent and divergent impacts on cortical neuron development and function

Nguyen, L. H., Xu, Y., Nair, M., & Bordey, A. (2024) · eLife · doi:10.7554/elife.91010.3 · Cited by 5 · see citing works

Second international symposium on the chaperone code, 2023

Büchner, J., Alasady, M. J., Backe, S. J., Blagg, B. S. J., Carpenter, R. L., Colombo, G., Gelis, I., Gewirth, D. T., Gierasch, L. M., Houry, W. A., et al. (2024) · Cell Stress and Chaperones · doi:10.1016/j.cstres.2024.01.003 · Cited by 4 · see citing works

The mTOR pathway genes mTOR , Rheb , Depdc5 , Pten , and Tsc1 have convergent and divergent impacts on cortical neuron development and functionPreprint

Nguyen, L. H., Xu, Y., Nair, M., & Bordey, A. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.08.11.553034 · Cited by 4 · see citing works

The lysosome and proteostatic stress at the intersection of pediatric neurological disorders and adult neurodegenerative diseases

Lane-Donovan, C., Paredes, M., & Kao, A. W. (2025) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2025.102854 · Cited by 3 · see citing works

Tuberous sclerosis complex‐1 (TSC1) contributes to selective neuronal vulnerability in Alzheimer's disease

Adriaanse, B. A., Brady, S., Wang, M., Beard, D. J., Spencer, J. I., Pansieri, J., Sutherland, B. A., Esiri, M. M., Buchan, A. M., Cader, Z., et al. (2023) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12904 · Cited by 2 · see citing works

The Role of Sirt1 in Regulating Inflammatory Cytokines and Oxidative Stress in the Transition Mechanism from Depressive Disorder to Alzheimer’s Disease

Zou, J., Liu, L., Chai, F., Shan, Q., & Wang, Y. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05084-0 · Cited by 3 · see citing works

Trade-off between search costs and accuracy in oculomotor and manual search tasks

Wagner, I., Tünnermann, J., Schubö, A., & Schütz, A. C. (2025) · Journal of Neurophysiology · doi:10.1152/jn.00488.2024 · Cited by 2 · see citing works

Comparing arm to whole-body motor control disambiguates age-related deterioration from compensation

Mathieu, R., Chambellant, F., Barbusse, D., Thomas, E., Papaxanthis, C., Hilt, P. M., Manckoundia, P., Mourey, F., & Gaveau, J. (2026) · Frontiers in Aging · doi:10.3389/fragi.2026.1715723 · Cited by 2 · see citing works

Microbial species exist and are maintained by ecological cohesiveness coupled to high homologous recombinationPreprint

Conrad, R. E., Brink, C. E., Viver, T., Rodriguez‐R, L. M., Aldeguer‐Riquelme, B., Hatt, J. K., Venter, S. N., Amann, R., Rossello-Mora, R. A., & Konstantinidis, K. T. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.05.25.595874 · Cited by 2 · see citing works

Understanding the impact of cytoskeleton disruption on synaptic plasticity in Alzheimer’s disease

Basavaraju, K. C., & Priyadarshini, P. (2025) · Advances in protein chemistry and structural biology · doi:10.1016/bs.apcsb.2025.10.020 · Cited by 1 · see citing works

READRetro: Natural Product Biosynthesis Planning with Retrieval-Augmented Dual-View RetrosynthesisPreprint

Lee, S., Kim, T., Choi, M., Kwak, Y., Park, J., Hwang, S. J., & Kim, S. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.03.21.533616 · Cited by 1 · see citing works

The mTOR pathway genes mTOR, Rheb, Depdc5, Pten, and Tsc1 have convergent and divergent impacts on cortical neuron development and functionPreprint

Nguyen, L. H., Xu, Y., Nair, M., & Bordey, A. (2023) · eLife · doi:10.7554/elife.91010.1 · Cited by 1 · see citing works

Tau isoform imbalance and aggregation are pathological hallmarks of X-linked dystonia-parkinsonismPreprint

Reyes, C. J., Domingo, A., Penney, E. B., Norenberg, E. P., Han, J., Murcar, M. G., Vaine, C. A., Bravo‐Vasquez, N., Tran, H., Quittot, N., et al. (2026) · medRxiv · doi:10.64898/2026.07.23.26358614 · Cited by 1 · see citing works

Genome mining of Streptomyces for the discovery of low-resistance antibioticsPreprint

Antony, R. A. S., Alejandro, A. H. M., Sánchez‐Cruz, N., & Ceapă, C. D. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.12.28.573565

The mTOR pathway genes mTOR, Rheb, Depdc5, Pten, and Tsc1 have convergent and divergent impacts on cortical neuron development and functionPreprint

Nguyen, L. H., Xu, Y., Nair, M., & Bordey, A. (2024) · eLife · doi:10.7554/elife.91010.2

Additional file 3 of Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteases

Sampognaro, P. J., Arya, S., Knudsen, G. M., Gunderson, E. L., Sandoval‐Pérez, A., Hodul, M., Bowles, K. R., Craik, C. S., Jacobson, M. P., & Kao, A. W. (2023) · Figshare · doi:10.6084/m9.figshare.22735429

Additional file 1 of Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteases

Sampognaro, P. J., Arya, S., Knudsen, G. M., Gunderson, E. L., Sandoval‐Pérez, A., Hodul, M., Bowles, K. R., Craik, C. S., Jacobson, M. P., & Kao, A. W. (2023) · Figshare · doi:10.6084/m9.figshare.22735420

Additional file 2 of Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteases

Sampognaro, P. J., Arya, S., Knudsen, G. M., Gunderson, E. L., Sandoval‐Pérez, A., Hodul, M., Bowles, K. R., Craik, C. S., Jacobson, M. P., & Kao, A. W. (2023) · Figshare · doi:10.6084/m9.figshare.22735423

Serotonergic psychedelics as epigenetic modulators: A paradigm shift in Alzheimer's disease therapeutics

Gojani, E. G., Farzin, H., Sutherland, R. J., & Mohajerani, M. H. (2026) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2026.106619

Dynamic blebbing and absence of organelle transfer during mouse oocyte formation

Aizawa, E., Shimamoto, S., Kajikawa, E., Hara, J., Abe, T., Shibuya, H., & Kitajima, T. S. (2026) · The EMBO Journal · doi:10.1038/s44318-026-00780-6

Multiomic Profiling of 85 iPSC Lines from Familial Dementia Reveals Cellular Diversity and Regulators of Organoid DevelopmentPreprint

Qi, L., Bertucci, T. B., Borden, S. M., Arduini, B. L., Lotz, S., Bowles, K. R., Goate, A., Karch, C. M. M., Temple, S., & Geschwind, D. H. (2026) · SSRN Electronic Journal · doi:10.64898/2026.04.29.721747

Synergetic inhibition of deubiquitinases and acetyltransferases to regulate tau acetylation and aggregation in SH-SY5Y cell line model of Alzheimer’s disease

C, B. K., K, H. D., & G., P. P. C. (2026) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/bs.mie.2026.05.034

Metformin modulates autophagy in heterozygous and CRISPR-edited TSC2 primary fibroblastsPreprint

Viola, G. D., Brum, P. O., Garcia, A. B. D. M., Jaeger, M. D. C., Freire, N., Filippi‐Chiela, E. C., Baldo, G., Poletto, É., Ashton‐Prolla, P., & Rosset, C. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.08.11.743350

Alcohol-induced dysregulation of tau and acetylation pathways in the pathogenesis of Alzheimer’s disease

Basavaraju, K., K, H. D., & G., P. P. C. (2026) · Neuroscience · doi:10.1016/j.neuroscience.2026.09.012

Autophagy-lysosomal pathway in neurodegeneration

McDonough, S. R., Rao, A. K., McAleer, J. M., Babrowicz, B. M., & Sharma, M. (2026) · Molecular Neurodegeneration Advances · doi:10.1186/s44477-026-00041-0

Chaperone-mediated autophagy in physiological homeostasis, disease and ageing

Kaushik, S., & Cuervo, A. M. (2026) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-026-01023-6

TSC1-mTORC1 signaling in Alzheimer’s disease: an integrated bioinformatic analysis linking gene expression to neuropathology

Liu, Z., Yu, Y., Wang, Y., Ning, S., Huang, T., Li, J., Fan, S., & 卢超龙 (2026) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2026.1920487

Targeting tau acetylation in Alzheimer's disease: Molecular mechanisms, pathological consequences, and therapeutic opportunities of dietary phytochemicals

Basavaraju, K. C., & G., P. P. C. (2026) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2026.154717

Mapping the Landscape of Tau Post-translational Modifications and Kinase-Specific Phosphorylation Signatures by Orthogonal CZE-MS/MS and NanoRPLC-MS/MS

Nimavard, R. T., Sadeghi, S. A., Colón-Rosado, J. A., Yue, Y., Fang, F., Hagar, H. C., Kuo, M.-H., & Sun, L. (2026) · Journal of Proteome Research · doi:10.1021/acs.jproteome.6c00539

Multi-omic profiling of 85 iPSC lines from familial dementia reveals cellular diversity and regulators of organoid development

Qi, L., Bertucci, T. B., Borden, S. M., Arduini, B. L., Lotz, S., Bowles, K. R., Goate, A., Karch, C. M. M., Temple, S., & Geschwind, D. H. (2026) · Neuron · doi:10.1016/j.neuron.2026.09.022

TSC1 loss-of-function increases risk for tauopathy by inducing tau acetylation and preventing autophagy-mediated tau clearancePreprint

Alquézar, C., Schoch, K. M., Geier, E. G., Ramos, E. M., Scrivo, A., Li, K. K., Argouarch, A. R., Mlynarski, E. E., Dombroski, B. A., Yokoyama, J. S., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.11.08.371922 · Cited by 1 · see citing works

Tau acetylation reduces its autophagic degradation and is a targetable pathway for human tauopathies

Johnson, N. R. (2022) · BioEssays · doi:10.1002/bies.202200062

Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice

Caballero, B., Bourdenx, M., Luengo, E., Diaz, A., Sohn, P. D., Chen, X., Wang, C., Juste, Y. R., Wegmann, S., Patel, B., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-22501-9 · Cited by 223 · see citing works

P3‐124: Exploiting the diversity of the chaperone repertoire to treat tauopathies

Jinwal, U. K., Abisambra, J. F., Koren, J., O’Leary, J. C., Blair, L. J., Hill, S. E., Trotter, J. H., Mushcol, M., Weeber, E. J., Gestwicki, J. E., et al. (2011) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2011.05.1565

Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy

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