The DOI matches its Crossref record; 57 of the 57 references it cites were found in a registry or an index.
A 10-micrometer-thick nanomesh-reinforced gas-permeable hydrogel skin sensor for long-term electrophysiological monitoring
Open accessAbstract
Hydrogel-enabled skin bioelectronics that can continuously monitor health for extended periods is crucial for early disease detection and treatment. However, it is challenging to engineer ultrathin gas-permeable hydrogel sensors that can self-adhere to the human skin for long-term daily use (>1 week). Here, we present a ~10-micrometer-thick polyurethane nanomesh–reinforced gas-permeable hydrogel sensor that can self-adhere to the human skin for continuous and high-quality electrophysiological monitoring for 8 days under daily life conditions. This research involves two key steps: (i) material design by gelatin-based thermal-dependent phase change hydrogels and (ii) robust thinness geometry achieved through nanomesh reinforcement. The resulting ultrathin hydrogels exhibit a thickness of ~10 micrometers with superior mechanical robustness, high skin adhesion, gas permeability, and anti-drying performance. To highlight the potential applications in early disease detection and treatment that leverage the collective features, we demonstrate the use of ultrathin gas-permeable hydrogels for long-term, continuous high-precision electrophysiological monitoring under daily life conditions up to 8 days.
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Strong tough hydrogels via the synergy of freeze-casting and salting out
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The stiffness of living tissues and its implications for tissue engineering
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Inflammation-free, gas-permeable, lightweight, stretchable on-skin electronics with nanomeshes
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Self-citationHan, L., Liu, K., Wang, M., Wang, K., Fang, L., Chen, H., Zhou, J., & Lu, X. (2018) · Advanced Functional Materials · doi:10.1002/adfm.201704195 · Cited by 1,160
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Design and applications of conductive polymers in wearable electrophysiological sensing
Zhou, N., Zhang, L., Cui, T., Wu, P., & Lei, Z. (2025) · Science China Technological Sciences · doi:10.1007/s11431-025-3114-6 · Cited by 9
Metadata
- Authors
- Zhang, Z., Yang, J., Wang, H., Wang, C., Gu, Y., Xu, Y., Lee, S., Yokota, T., Haick, H., Someya, T., & Wang, Y.
- Venue
- Science Advances
- Published
- 2024-01-12
- Volume
- 10
- Issue
- 2
- Pages
- eadj5389-eadj5389
- ISSN
- 2375-2548 (ISSN-L)
- OpenAlex
- W4390717536
- Cited by
- 292
- References
- 57
- FWCI
- 30.67
- Type
- journal article
- Language
- en
- Open access
- gold
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- The paper
- Zhang, Z., Yang, J., Wang, H., Wang, C., Gu, Y., Xu, Y., Lee, S., Yokota, T., Haick, H., Someya, T., & Wang, Y. (2024). A 10-micrometer-thick nanomesh-reinforced gas-permeable hydrogel skin sensor for long-term electrophysiological monitoring. Science Advances. https://doi.org/10.1126/sciadv.adj5389
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