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RNA Silencing in Plants--Defense and Counterdefense
Abstract
RNA silencing is a remarkable type of gene regulation based on sequence-specific targeting and degradation of RNA. The term encompasses related pathways found in a broad range of eukaryotic organisms, including fungi, plants, and animals. In plants, it serves as an antiviral defense, and many plant viruses encode suppressors of silencing. The emerging view is that RNA silencing is part of a sophisticated network of interconnected pathways for cellular defense, RNA surveillance, and development and that it may become a powerful tool to manipulate gene expression experimentally.
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Citations
Cited by
Bartel (2004) · doi:10.1016/s0092-8674(04)00045-5 · Cited by 34,714
The microRNAs of Caenorhabditis elegans
Lim, L. P., Lau, N. C., Weinstein, E. G., Abdelhakim, A., Yekta, S., Rhoades, M. W., Burge, C. B., & Bartel, D. P. (2003) · Genes & Development · doi:10.1101/gad.1074403 · Cited by 1,259
miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs
Mourelatos, Z., Dostie, J., Paushkin, S., Sharma, A., Charroux, B., Abel, L., Rappsilber, J., Mann, M., & Dreyfuss, G. (2002) · Genes & Development · doi:10.1101/gad.974702 · Cited by 1,105
Kasschau, K. D., Xie, Z., Allen, E., Llave, C., Chapman, E. J., Krizan, K. A., & Carrington, J. C. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00025-x · Cited by 968
Short interfering RNA confers intracellular antiviral immunity in human cells
Gitlin, L., Karelsky, S., & Andino, R. (2002) · Nature · doi:10.1038/nature00873 · Cited by 608
Metadata
- Authors
- Vance, V., & Vaucheret, H.
- Venue
- Science
- Published
- 2001-06-22
- Volume
- 292
- Issue
- 5525
- Pages
- 2277-2280
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2155985666
- Cited by
- 598
- References
- 0
- FWCI
- 96.24
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
