The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Crystal Structure of a Carbon Monoxide Dehydrogenase Reveals a [Ni-4Fe-5S] Cluster
Abstract
The homodimeric nickel-containing CO dehydrogenase from the anaerobic bacterium Carboxydothermus hydrogenoformans catalyzes the oxidation of CO to CO 2 . A crystal structure of the reduced enzyme has been solved at 1.6 angstrom resolution. This structure represents the prototype for Ni-containing CO dehydrogenases from anaerobic bacteria and archaea. It contains five metal clusters of which clusters B, B′, and a subunit-bridging, surface-exposed cluster D are cubane-type [4Fe-4S] clusters. The active-site clusters C and C′ are novel, asymmetric [Ni-4Fe-5S] clusters. Their integral Ni ion, which is the likely site of CO oxidation, is coordinated by four sulfur ligands with square planar geometry.
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Cites
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Holm, L., & Sander, C. (1993) · Journal of Molecular Biology · doi:10.1006/jmbi.1993.1489 · Cited by 3,984
Iron-sulfur proteins: ancient structures, still full of surprises
Beinert, H. (2000) · JBIC Journal of Biological Inorganic Chemistry · doi:10.1007/s007750050002 · Cited by 667
Sulfite Reductase Structure at 1.6 Å: Evolution and Catalysis for Reduction of Inorganic Anions
Crane, B. R., Siegel, L. M., & Getzoff, E. D. (1995) · Science · doi:10.1126/science.270.5233.59 · Cited by 345
Cited by
Structure, function, and formation of biological iron-sulfur clusters
Johnson, D. C., Dean, D. R., Smith, A. D., & Johnson, M. K. (2005) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.74.082803.133518 · Cited by 1,438
The rocky roots of the acetyl-CoA pathway
Russell, M. J., & Martin, W. (2004) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2004.05.007 · Cited by 432
Catalysis at a dinuclear [CuSMo(O)OH] cluster in a CO dehydrogenase resolved at 1.1-Å resolution
Dobbek, H., Gremer, L., Kiefersauer, R., Huber, R., & Meyer, O. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.212640899 · Cited by 386
Self-citationThe Drive to Life on Wet and Icy Worlds
Russell, M. J., Barge, L. M., Bhartia, R., Bocanegra, D., Bracher, P. J., Branscomb, E., Kidd, R., McGlynn, S., Meier, D. H., Nitschke, W., et al. (2014) · Astrobiology · doi:10.1089/ast.2013.1110 · Cited by 288
“In our hypothesis, the catalyst for this reaction is a nickel-bearing greigite cluster (SNiS[Fe4S4] SFeS), the assumed precursor of carbon monoxide dehydrogenase (cf. Vaughan and Craig, 1978; Dobbek et al., 2001) (Fig.”
A hydrogen-dependent geochemical analogue of primordial carbon and energy metabolism
Preiner, M., Igarashi, K., Muchowska, K. B., Yu, M., Varma, S. J., Kleinermanns, K., Nobu, M. K., Kamagata, Y., Tüysüz, H., Moran, J., et al. (2020) · Nature Ecology & Evolution · doi:10.1038/s41559-020-1125-6 · Cited by 272
Metadata
- Authors
- Dobbek, H., Svetlitchnyi, V., Gremer, L., Huber, R., & Meyer, O.
- Venue
- Science
- Published
- 2001-08-17
- Volume
- 293
- Issue
- 5533
- Pages
- 1281-1285
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2034063871
- Cited by
- 570
- References
- 3
- FWCI
- 33.10
- Type
- journal article
- Language
- en
- Open access
- closed
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