The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Controlling the Caspases
Abstract
Enzymes called caspases are the executioners of programmed cell death. The IAP (inhibitor of apoptosis) proteins suppress apoptosis by blocking caspase activity and this suppression can be relieved by Smac/DIABLO, a mitochondrial protein released into the cytosol in response to apoptotic stimuli. In their Perspective, Fesik and Shi discuss recent structural and biochemical studies that reveal the molecular basis for the inhibition of caspases by IAPs and the relief of IAP inhibition by Smac/DIABLO.
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Citations
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Apoptosis in the Pathogenesis and Treatment of Disease
Thompson, C. B. (1995) · Science · doi:10.1126/science.7878464 · Cited by 6,524
Cited by
IAP proteins: blocking the road to death's door
Salvesen, G. S., & Duckett, C. S. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm830 · Cited by 1,756
Dou, D., Kale, S. D., Wang, X., Chen, Y., Wang, Q., Wang, X., Jiang, R. H. Y., Arredondo, F. D., Anderson, R. G., Thakur, P. B., et al. (2008) · The Plant Cell · doi:10.1105/tpc.107.057067 · Cited by 339
Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer.
Yadav, V. R., Prasad, S., Sung, B., Kannappan, R., & Aggarwal, B. B. (2010) · Toxins · doi:10.3390/toxins2102428 · Cited by 320
Drug Insight: cancer therapy strategies based on restoration of endogenous cell death mechanisms
Reed, J. C. (2006) · Nature Clinical Practice Oncology · doi:10.1038/ncponc0538 · Cited by 179
The Role of Reactive Oxygen Species and Ferroptosis in Heme-Mediated Activation of Human Platelets
NaveenKumar, S. K., SharathBabu, B. N., Hemshekhar, M., Kemparaju, K., Girish, K. S., & Mugesh, G. (2018) · ACS Chemical Biology · doi:10.1021/acschembio.8b00458 · Cited by 137
Metadata
- Authors
- Fesik, S. W., & Shi, Y.
- Venue
- Science
- Published
- 2001-11-16
- Volume
- 294
- Issue
- 5546
- Pages
- 1477-1478
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1608873327
- Cited by
- 170
- References
- 1
- FWCI
- 3.04
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
