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Cited by 270

The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.

Transcriptional Regulation of Cortical Neuron Migration by POU Domain Factors

McEvilly, Robert J., de Diaz, Marcela Ortiz, Schonemann, Marcus D., Hooshmand, Farideh, Rosenfeld, Michael G.·2002·Science

Abstract

The identification of pathways mediated by the kinase Cdk5 and the ligand reelin has provided a conceptual framework for exploring the molecular mechanisms underlying proper lamination of the developing mammalian cerebral cortex. In this report, we identify a component of the regulation of Cdk5-mediated cortical lamination by genetic analysis of the roles of the class III POU domain transcription factors, Brn-1 and Brn-2, expressed during the development of the forebrain and coexpressed in most layer II-V cortical neurons. Brn-1 and Brn-2 appear to critically control the initiation of radial migration, redundantly regulating the cell-autonomous expression of the p35 and p39 regulatory subunits of Cdk5 in migrating cortical neurons, with Brn-1 ( − /−)/ Brn-2 ( − /−) mice exhibiting cortical inversion.

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Crossref · 10.1126/science.1067132

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Metadata

Authors
McEvilly, R. J., de Diaz, M. O., Schonemann, M. D., Hooshmand, F., & Rosenfeld, M. G.
Venue
Science
Published
2002-02-22
Volume
295
Issue
5559
Pages
1528-1532
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W1970323747
Cited by
270
References
20
FWCI
3.43
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Transcriptional Regulation of Cortical Neuron Migration by POU Domain Factors. https://app.cochat.ai/papers/10.1126/science.1067132
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McEvilly, R. J., de Diaz, M. O., Schonemann, M. D., Hooshmand, F., & Rosenfeld, M. G. (2002). Transcriptional Regulation of Cortical Neuron Migration by POU Domain Factors. Science. https://doi.org/10.1126/science.1067132

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.