The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Ancient Pathways Programmed by Small RNAs
Abstract
Double-stranded RNA can now be used in a wide variety of eukaryotes to suppress the expression of virtually any gene, allowing the rapid analysis of that gene's function, a technique known as RNA interference. But how cells use the information in double-stranded RNA to suppress gene expression and why they contain the machinery to do so remain the subjects of intense scrutiny. Current evidence suggests that RNA interference and other “RNA silencing” phenomena reflect an elaborate cellular apparatus that eliminates abundant but defective messenger RNAs and defends against molecular parasites such as transposons and viruses.
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Citations
Cites
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E., & Mello, C. C. (1998) · Nature · doi:10.1038/35888 · Cited by 15,429
Cited by
Specificity of microRNA target selection in translational repression
Doench, J. G., & Sharp, P. A. (2004) · Genes & Development · doi:10.1101/gad.1184404 · Cited by 1,636
A uniform system for microRNA annotation
AMBROS, V., BARTEL, B., BARTEL, D. P., BURGE, C. B., CARRINGTON, J. C., CHEN, X., DREYFUSS, G., EDDY, S. R., GRIFFITHS-JONES, S., MARSHALL, M., et al. (2003) · RNA · doi:10.1261/rna.2183803 · Cited by 1,553
Park, W., Li, J., Song, R., Messing, J., & Chen, X. (2002) · Current Biology · doi:10.1016/s0960-9822(02)01017-5 · Cited by 1,244
Molecular mechanisms of translational control
Gebauer, F., & Hentze, M. W. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1488 · Cited by 991
The Small RNA Profile during Drosophila melanogaster Development
Aravin, A. A., Lagos-Quintana, M., Yalcin, A., Zavolan, M., Marks, D., Snyder, B., Gaasterland, T., Meyer, J., & Tuschl, T. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00228-4 · Cited by 802
Metadata
- Authors
- Zamore, P. D.
- Venue
- Science
- Published
- 2002-05-17
- Volume
- 296
- Issue
- 5571
- Pages
- 1265-1269
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2115678473
- Cited by
- 360
- References
- 1
- FWCI
- 20.95
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
