The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Cytoprotective Role of Ca 2+ - Activated K + Channels in the Cardiac Inner Mitochondrial Membrane
Abstract
Ion channels on the mitochondrial inner membrane influence cell function in specific ways that can be detrimental or beneficial to cell survival. At least one type of potassium (K + ) channel, the mitochondrial adenosine triphosphate–sensitive K + channel (mitoK ATP ), is an important effector of protection against necrotic and apoptotic cell injury after ischemia. Here another channel with properties similar to the surface membrane calcium-activated K + channel was found on the mitochondrial inner membrane (mitoK Ca ) of guinea pig ventricular cells. MitoK Ca significantly contributed to mitochondrial K + uptake of the myocyte, and an opener of mitoK Ca protected hearts against infarction.
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Cites
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Cited by
Calcium signaling and apoptosis
Hajnóczky, G., Davies, E., & Madesh, M. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)00616-8 · Cited by 462
The role of mitochondria in protection of the heart by preconditioning
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Redox Nanodomains Are Induced by and Control Calcium Signaling at the ER-Mitochondrial Interface
Booth, D. M., Enyedi, B., Geiszt, M., Várnai, P., & Hajnóczky, G. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.05.040 · Cited by 308
Molecular Determinants of BK Channel Functional Diversity and Functioning
Latorre, R., Castillo, K., Carrasquel-Ursulaez, W., Sepulveda, R. V., Gonzalez-Nilo, F., Gonzalez, C., & Alvarez, O. (2017) · Physiological Reviews · doi:10.1152/physrev.00001.2016 · Cited by 271
Proteomic analysis of the mouse liver mitochondrial inner membrane
Da Cruz, S., Xenarios, I., Langridge, J., Vilbois, F., Parone, P. A., & Martinou, J.-C. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m304940200 · Cited by 247
Metadata
- Authors
- Xu, W., Liu, Y., Wang, S., McDonald, T., Van Eyk, J. E., Sidor, A., & O'Rourke, B.
- Venue
- Science
- Published
- 2002-11
- Volume
- 298
- Issue
- 5595
- Pages
- 1029-1033
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2024104987
- Cited by
- 477
- References
- 25
- FWCI
- 14.30
- Type
- journal article
- Language
- en
- Open access
- closed
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- Xu, W., Liu, Y., Wang, S., McDonald, T., Van Eyk, J. E., Sidor, A., & O'Rourke, B. (2002). Cytoprotective Role of Ca 2+ - Activated K + Channels in the Cardiac Inner Mitochondrial Membrane. Science. https://doi.org/10.1126/science.1074360
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
