The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Specification of Jaw Subdivisions by Dlx Genes
Open accessAbstract
The success of vertebrates was due in part to the acquisition and modification of jaws. Jaws are principally derived from the branchial arches, embryonic structures that exhibit proximodistal polarity. To investigate the mechanisms that specify the identity of skeletal elements within the arches, we examined mice lacking expression of Dlx5 and Dlx6 , linked homeobox genes expressed distally but not proximally within the arches. Dlx5/6 –/– mutants exhibit a homeotic transformation of lower jaws to upper jaws. We suggest that nested Dlx expression in the arches patterns their proximodistal axes. Evolutionary acquisition and subsequent refinement of jaws may have been dependent on modification of Dlx expression.
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Neural Crest and the Origin of Vertebrates: A New Head
Gans, C., & Northcutt, R. G. (1983) · Science · doi:10.1126/science.220.4594.268 · Cited by 1,053
Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation
Satokata, I., Ma, L., Ohshima, H., Bei, M., Woo, I., Nishizawa, K., Maeda, T., Takano, Y., Uchiyama, M., Heaney, S., et al. (2000) · Nature Genetics · doi:10.1038/74231 · Cited by 737
Hindlimb patterning and mandible development require the Ptx1 gene
Lanctôt, C., Moreau, A., Chamberland, M., Tremblay, M. L., & Drouin, J. (1999) · Development · doi:10.1242/dev.126.9.1805 · Cited by 311
Cited by
Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia
Jeong, J., Mao, J., Tenzen, T., Kottmann, A. H., & McMahon, A. P. (2004) · Genes & Development · doi:10.1101/gad.1190304 · Cited by 615
Minoux, M., & Rijli, F. M. (2010) · Development · doi:10.1242/dev.040048 · Cited by 507
Mechanisms of ectodermal organogenesis.
Pispa, J., & Thesleff, I. (2003) · Developmental Biology · doi:10.1016/s0012-1606(03)00325-7 · Cited by 499
Cranial neural crest and the building of the vertebrate head
Santagati, F., & Rijli, F. M. (2003) · Nature Reviews Neuroscience · doi:10.1038/nrn1221 · Cited by 461
Dose-dependent functions of Fgf8 in regulating telencephalic patterning centers
Storm, E. E., Garel, S., Borello, U., Hebert, J. M., Martinez, S., McConnell, S. K., Martin, G. R., & Rubenstein, J. L. R. (2006) · Development · doi:10.1242/dev.02324 · Cited by 366
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Metadata
- Authors
- Depew, M. J., Lufkin, T., & Rubenstein, J. L. R.
- Venue
- Science
- Published
- 2002-10-11
- Volume
- 298
- Issue
- 5592
- Pages
- 381-385
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2070270500
- Cited by
- 465
- References
- 3
- FWCI
- 7.34
- Type
- journal article
- Language
- en
- Open access
- bronze
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