The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Macromolecular Architecture in Eukaryotic Cells Visualized by Cryoelectron Tomography
Abstract
Electron tomography of vitrified cells is a noninvasive three-dimensional imaging technique that opens up new vistas for exploring the supramolecular organization of the cytoplasm. We applied this technique to Dictyostelium cells, focusing on the actin cytoskeleton. In actin networks reconstructed without prior removal of membranes or extraction of soluble proteins, the cross-linking of individual microfilaments, their branching angles, and membrane attachment sites can be analyzed. At a resolution of 5 to 6 nanometers, single macromolecules with distinct shapes, such as the 26 S proteasome, can be identified in an unperturbed cellular environment.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Calreticulin and calnexin in the endoplasmic reticulum are important for phagocytosis
Müller‐Taubenberger, A., Lupas, A. N., Li, H., Ecke, M., Simmeth, E., & Gerisch, G. (2001) · The EMBO Journal · doi:10.1093/emboj/20.23.6772 · Cited by 242
Self-citation
Cited by
Ellis, R. J., & Minton, A. P. (2003) · Nature · doi:10.1038/425027a · Cited by 894
Native mass spectrometry: a bridge between interactomics and structural biology
Heck, A. J. R. (2008) · Nature Methods · doi:10.1038/nmeth.1265 · Cited by 766
Three-Dimensional Structure of Herpes Simplex Virus from Cryo-Electron Tomography
Grünewald, K., Desai, P., Winkler, D. C., Heymann, J. B., Belnap, D. M., Baumeister, W., & Steven, A. C. (2003) · Science · doi:10.1126/science.1090284 · Cited by 586
Self-citationOutcome of the first electron microscopy validation task force meeting
Henderson, R., Sali, A., Baker, M. L., Carragher, B., Devkota, B., Downing, K. H., Egelman, E. H., Feng, Z., Frank, J., Grigorieff, N., et al. (2012) · Structure · doi:10.1016/j.str.2011.12.014 · Cited by 505
Self-citationStructure-Based Assembly of Protein Complexes in Yeast
Aloy, P., Böttcher, B., Ceulemans, H., Leutwein, C., Mellwig, C., Fischer, S., Gavin, A.-C., Bork, P., Superti-Furga, G., Serrano, L., et al. (2004) · Science · doi:10.1126/science.1092645 · Cited by 383
Metadata
- Authors
- Medalia, O., Weber, I., Frangakis, A. S., Nicastro, D., Gerisch, G., & Baumeister, W.
- Venue
- Science
- Published
- 2002-11-08
- Volume
- 298
- Issue
- 5596
- Pages
- 1209-1213
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2025042015
- Cited by
- 837
- References
- 1
- FWCI
- 51.90
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Macromolecular Architecture in Eukaryotic Cells Visualized by Cryoelectron Tomography. https://app.cochat.ai/papers/10.1126/science.1076184
- The paper
- Medalia, O., Weber, I., Frangakis, A. S., Nicastro, D., Gerisch, G., & Baumeister, W. (2002). Macromolecular Architecture in Eukaryotic Cells Visualized by Cryoelectron Tomography. Science. https://doi.org/10.1126/science.1076184
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
