Finding genes that underlie complex traits.

Glazier, Anne M., Nadeau, Joseph H., Aitman, Timothy J.·2002·Science

Cited by (855)

Items 401–500 of 855

  1. Do we need more twin studies? The Healthy Twin Study, Korea
    Joohon Sung, Sung‐Il Cho, Yun‐Mi Song, Kayoung Lee, EUN-YOUNG CHOI, Mina Ha, Ji‐Hae Kim, Ho Kim, Yeon-Ju Kim, Eun-Kyung Shin et al. · 2006 · International Journal of Epidemiology
  2. PANDA: Prioritization of autism‐genes using network‐based deep‐learning approach
    Yu Zhang, Yuanzhu Chen, Ting Hu · 2020 · Genetic Epidemiology
  3. Comparative Genomics for Detecting Human Disease Genes
    Carol Moreno, Jozef Lazar, Howard J. Jacob, Anne E. Kwitek · 2008 · Advances in genetics
  4. A Leishmania major Response Locus Identified by Interval-specific Congenic Mapping of a T Helper Type 2 Cell Bias-controlling Quantitative Trait Locus
    Aurélie Baguet, Jennifer Epler, Kwun Wah Wen, Mark Bix · 2004 · The Journal of Experimental Medicine
  5. Primer on Medical Genomics Part VIII: Essentials of Medical Genetics for the Practicing Physician
    Regina E. Ensenauer, Shanda S. Reinke, Michael John Ackerman, David J. Tester, David A. H. Whiteman, Ayalew Tefferi · 2003 · Mayo Clinic Proceedings
  6. Single and multiple congenic strains for hydrocephalus in the H-Tx rat
    Hazel C. Jones, Gin‐Fu Chen, Baligh Ramzi Yehia, Barbara J. Carter, Elizabeth J. Akins, Logan C. Wolpin · 2005 · Mammalian Genome
  7. Rats deficient in the GAD65 isoform exhibit epilepsy and premature lethality
    Toshikazu Kakizaki, Tomokazu Ohshiro, Makoto Itakura, Kohtarou Konno, Masahiko Watanabe, Hajime Mushiake, Yuchio Yanagawa · 2020 · The FASEB Journal
  8. Average semivariance yields accurate estimates of the fraction of marker-associated genetic variance and heritability in complex trait analyses
    Mitchell J. Feldmann, Hans‐Peter Piepho, William C. Bridges, Steven J. Knapp · 2021 · PLoS Genetics
  9. Antimicrobial mouthrinses and the management of periodontal diseases
    Ira B. Lamster · 2006 · The Journal of the American Dental Association
  10. Epistatic effect of plasminogen activator inhibitor 1 and β‐Fibrinogen genes on risk of glomerular microthrombosis in lupus nephritis: Interaction with environmental/clinical factors
    Rujun Gong, Zhihong Liu, LI Leishi · 2007 · Arthritis & Rheumatism
  11. Network medicine in drug design: implications for neuroinflammation
    Sourish Ghosh, Anirban Basu · 2012 · Drug Discovery Today
  12. GENETIC STUDY: Interaction of SLC6A4 and DRD2 polymorphisms is associated with a history of delirium tremens
    Victor M. Karpyak, Joanna M. Biernacka, Mark W. Vander Weg, Susanna R. Stevens, Julie M. Cunningham, David A. Mrazek, John Logan Black · 2009 · Addiction Biology
  13. Role of Centrality in Network-Based Prioritization of Disease Genes
    Sinan Erten, Mehmet Koyutürk · 2010 · Lecture notes in computer science
  14. Genomics for food safety and sustainable animal production
    B. Harlizius, Rik van Wijk, Jan W.M. Merks · 2004 · Journal of Biotechnology
  15. Commentary: Understanding sources of complexity in chronic diseases—the importance of integration of genetics and epidemiology
    Kathleen Ries Merikangas, Nancy C. P. Low, John Hardy · 2006 · International Journal of Epidemiology
  16. Genetic analysis of the Trichuris muris-induced model of colitis reveals QTL overlap and a novel gene cluster for establishing colonic inflammation
    Scott Levison, Paul Fisher, Jenny Hankinson, Leo A. H. Zeef, Stephen Eyre, William Ollier, John T. McLaughlin, Andy Brass, Richard K. Grencis, Joanne L. Pennock · 2013 · BMC Genomics
  17. Systems genetics reveals key genetic elements of drought induced gene regulation in diploid potato
    Dennis van Muijen, A. M. Anithakumari, Chris A. Maliepaard, Richard G. F. Visser, C. Gerard van der Linden · 2016 · Plant Cell & Environment
  18. Complete and overlapping congenics proving the existence of a quantitative trait locus for blood pressure on Dahl rat chromosome 17
    Myrian Grondin, Vasiliki Eliopoulos, Raphaëlle Lambert, Yishu Deng, Anita Ariyarajah, Myriam Moujahidine, Julie Dutil, Sophie Charron, Alan Y. Deng · 2005 · Physiological Genomics
  19. Fragmentation of Two Quantitative Trait Loci Controlling Collagen-Induced Arthritis Reveals a New Set of Interacting Subloci
    Emma Ahlqvist, Robert Bockermann, Rikard Holmdahl · 2007 · The Journal of Immunology
  20. Concordance of functional in vitro data and epidemiological associations in complex disease genetics
    John P. A. Ioannidis, Fotini K. Kavvoura · 2006 · Genetics in Medicine
  21. The thyroglobulin gene as the first thyroid-specific susceptibility gene for autoimmune thyroid disease
    Yaron Tomer, David A. Greenberg · 2004 · Trends in Molecular Medicine
  22. Hunting for immune response regulatory genes: vaccination studies in infant twins
    Melanie J. Newport, Tessa Goetghebuer, Arnaud Marchant · 2005 · Expert Review of Vaccines
  23. Pharmacogenomics of Metabolic Effects of Rosiglitazone
    Ond⊘řej Šeda, Lucie Šedová, Olena Oliyarnyk, Ludmila Kazdová, Drahomíra K⊘enová, Gilles Corbeil, Pavel Hamet, Johanne Tremblay, Vladimír K⊘en · 2008 · Pharmacogenomics
  24. Integrated gene expression profiling and linkage analysis in the rat
    Enrico G. Petretto, Jonathan Mangion, Michal Pravenec, Norbert Hübner, Timothy J. Aitman · 2006 · Mammalian Genome
  25. Quantitative Trait Loci Specifying the Response of Body Temperature to Dietary Restriction
    Brad A. Rikke, John Yerg, Matthew E. Battaglia, Tim R. Nagy, David B. Allison, Thomas E. Johnson · 2004 · The Journals of Gerontology Series A
  26. Clinical application of genetic risk assessment strategies for coronary artery disease: genotypes, phenotypes, and family history
    Maren Theresa Scheuner · 2004 · Primary Care Clinics in Office Practice
  27. Associations between temperament and gene polymorphisms in the brain dopaminergic system and the adrenal gland of sheep
    Xiaoyan Qiu, Jason M. Ledger, Chen Zheng, Graeme Bruce Martin, Dominique Blache · 2015 · Physiology & Behavior
  28. Examination of Clock and Adcyap1 gene variation in a neotropical migratory passerine
    Andrea J. Contina, Eli S. Bridge, Jeremy D. Ross, Jeremy Ryan Shipley, Jeffrey F. Kelly · 2018 · PLoS ONE
  29. Ashkenazi Jewish Centenarians Do Not Demonstrate Enrichment in Mitochondrial Haplogroup J
    Liran I. Shlush, Gil Atzmon, Roni Weisshof, Doron M. Behar, Guenady Yudkovsky, Nir Barzilai, Karl L. Skorecki · 2008 · PLoS ONE
  30. Chromosome Substitution Strains
    Annie E. Hill, Eric S. Lander, Joseph H. Nadeau · 2006 · Methods in molecular medicine
  31. Primer: strategies for identifying genes involved in renal disease
    Martin H. de Borst, Ariela Benigni, Giuseppe Remuzzi · 2008 · Nature Reviews Nephrology
  32. Molecular screening and association studies of retinoid-related orphan receptor γ (RORC): a positional and functional candidate for type 2 diabetes
    Hua Wang, Winston S. Chu, Swapan K. Das, Zhengxian Zheng, Sandra J. Hasstedt, Steven C. Elbein · 2003 · Molecular Genetics and Metabolism
  33. A microsatellite genetic linkage map of half smooth tongue sole (Cynoglossus semilaevis)
    Liming Jiang, Guannan Chu, Quanqi Zhang, Zhigang Wang, Xubo Wang, Jieming Zhai, Haiyang Yu · 2012 · Marine Genomics
  34. Prioritization of candidate disease genes for metabolic syndrome by computational analysis of its defining phenotypes
    Nicki Tiffin, Ikechi Gareth Okpechi, Carolina Perez‐Iratxeta, Miguel Angel Andrade-Navarro, Raj Ramesar · 2008 · Physiological Genomics
  35. A systematic strategy for the discovery of candidate genes responsible for phenotypic variation
    Paul Fisher, Cornelia Hedeler, Katherine Wolstencroft, Helen Hulme, Harry A. Noyes, Stephen J. Kemp, Robert Stevens, Andy Brass · 2007 · BMC Bioinformatics
  36. Pharmacogenomics of adrenoceptors
    Christos S. Flordellis, H J Paris, Andreas Karabinis, Anastasios Lymperopoulos · 2004 · Pharmacogenomics
  37. MCMC‐based linkage analysis for complex traits on general pedigrees: multipoint analysis with a two‐locus model and a polygenic component
    Yun Ju Sung, E. A. Thompson, Ellen M. Wijsman · 2006 · Genetic Epidemiology
  38. Positional Cloning of Ncf1– a Piece in the Puzzle of Arthritis Genetics
    Peter Olofsson, Rikard Holmdahl · 2003 · Scandinavian Journal of Immunology
  39. The future of motor neuron disease
    Jan Herman Veldink, Leonard H. van den Berg, John H. J. Wokke · 2004 · Journal of Neurology
  40. The comparative patterns of linkade disequilibrium in European populations and its implication for genetic association studies
    Elin Lõhmussaar · 2006 · DSpace repository (University of Tartu)
  41. Second generation physical and linkage maps of yellowtail (Seriola quinqueradiata) and comparison of synteny with four model fish
    Jun-ya Aoki, Wataru Kai, Yumi Kawabata, Akiyuki Ozaki, Kazunori Yoshida, Takashi Koyama, Takashi Sakamoto, Kazuo Araki · 2015 · BMC Genomics
  42. Evidence for epistatic interactions in antiepileptic drug resistance
    Myeong‐Kyu Kim, Jason H. Moore, Jong-Ki Kim, Ki-Hyun Cho, Yong Won Cho, Yo-Sik Kim, Min Cheol Lee, Young‐Ok Kim, Min‐Ho Shin · 2010 · Journal of Human Genetics
  43. A new gene for hybrid sterility from a cross between Oryza sativa and O. glaberrima
    Fei Li, F. H. Liu, D. Morinaga, Zhigang Zhao · 2011 · Plant Breeding
  44. Identifying Multi-Omics Causers and Causal Pathways for Complex Traits
    Huaizhen Qin, Tianhua Niu, Jinying Zhao · 2019 · Frontiers in Genetics
  45. Genetics of cholestatic liver disease in 2010
    Tom H. Karlsen, Johannes R. Hov · 2010 · Current Opinion in Gastroenterology
  46. Mouse Inbred Strain Sequence Information and Yin-Yang Crosses for Quantitative Trait Locus Fine Mapping
    Sagiv Shifman, Ariel Darvasi · 2004 · Genetics
  47. Brain Gene Expression: Genomics and Genetics
    Elissa J. Chesler, Robert W. Williams · 2004 · International review of neurobiology
  48. Mixed modelling to characterize genotype–phenotype associations
    Andrea S. Foulkes, Muredach P. Reilly, L. Zhou, Megan Wolfe, Daniel James Rader · 2005 · Statistics in Medicine
  49. Genetic Medicine and Obesity
    Timothy J. Aitman · 2003 · New England Journal of Medicine
  50. Association mapping of morphological traits in wild and captive zebra finches: reliable within, but not between populations
    Knief, Ulrich, Schielzeth, Holger, Backström, Niclas, Hemmrich‐Stanisak, Georg, Wittig, Michael, Franke, Andre, Griffith, Simon C., Ellegren, Hans, Kempenaers, Bart, Forstmeier, Wolfgang · 2017 · Molecular Ecology
  51. Molecular diagnostics: between chips and customized medicine
    Giuseppe Castaldo, Francesca Lembo, Rossella Tomaiuolo · 2010 · Clinical Chemistry and Laboratory Medicine (CCLM)
  52. Understanding the fundamentals of microbial remediation with emphasize on metabolomics
    Jeevanandam Vaishnavi, Jabez William Osborne · 2021 · Preparative Biochemistry & Biotechnology
  53. Does Marriage Moderate Genetic Effects on Delinquency and Violence?
    Yi Li, Hexuan Liu, Guang Guo · 2015 · Journal of Marriage and the Family
  54. Genome-wide Association Studies
    Emma L. Duncan, Matthew Arthur Brown · 2012 · Elsevier eBooks
  55. Structure and allele-specific expression variation of novel α/β hydrolase fold proteins in gentian plants
    Takashi Hikage, Yasushi Saitoh, Claire Tanaka-Saito, Hisakazu Hagami, Fumi Satou, Yoshitaka Shimotai, Yuki Nakano, Miho Takahashi, Yoshihito Takahata, Ken‐ichi Tsutsumi · 2007 · Molecular Genetics and Genomics
  56. The Incidentalome—Reply
    Isaac S. Kohane, Daniel R. Masys, Russ Biagio Altman · 2006 · JAMA
  57. Intersubspecific subcongenic mouse strain analysis reveals closely linked QTLs with opposite effects on body weight
    Md. Bazlur Rahman Mollah, Akira Ishikawa · 2011 · Mammalian Genome
  58. Principles in genetic risk assessment
    Pedro Viana Baptista · 2005 · Therapeutics and Clinical Risk Management
  59. Genetic Susceptibility to Prion Diseases in Humans and Mice
    Sarah E. Lloyd, John Collinge · 2005 · Current Genomics
  60. Complex Genetics of Interactions of Alcohol and CNS Function and Behavior
    Douglas B. Matthews, Sanjiv V. Bhave, John K. Belknap, Cynthia Brittingham, Elissa J. Chesler, ROBERT J. HITZEMANN, Paula L. Hoffmann, Lu Lu, Shannon K. McWeeney, Michael F. Miles et al. · 2005 · Alcoholism Clinical and Experimental Research
  61. Quantitative trait loci for steady-state platelet count in mice
    Carol C. Cheung, Ian C. A. Martin, Kyall Richard Zenger, Jennifer A. Donald, Peter Campbell Thomson, Christopher Moran, Michael Francis Buckley · 2004 · Mammalian Genome
  62. Functional Genomics of Blood Pressure Determination: Dissecting and Assembling a Polygenic Trait by Experimental Genetics
    Alan Y. Deng · 2005 · Current Hypertension Reviews
  63. A Bayesian Multilocus Association Method: Allowing for Higher-Order Interaction in Association Studies
    Anders Albrechtsen, Sofie Castella, Gitte Andersen, Torben F. Hansen, Oluf Borbye Pedersen, Rasmus Nielsen · 2007 · Genetics
  64. Genetic regulation of canine skeletal traits: trade-offs between the hind limbs and forelimbs in the fox and dog
    Anastasia V. Kharlamova, Lyudmila N. Trut, David R. Carrier, Kevin Chase, Karl G. Lark · 2007 · Integrative and Comparative Biology
  65. The evolution of signaling complexity suggests a mechanism for reducing the genomic search space in human association studies
    Kristopher J. L. Irizarry, Barry Merriman, M E Bahamonde, Ma‐Li Wong, Júlio Licinio · 2004 · Molecular Psychiatry
  66. Copies count
    Joseph H. Nadeau, Charles Lee · 2006 · Nature
  67. Pharmacogenomics of primary hypertension – the lessons from the past to look toward the future
    Giuseppe Bianchi, Jan Albert Staessen, Ferrari Patrizia · 2003 · Pharmacogenomics
  68. Prioritizing Disease Candidate Proteins in Cardiomyopathy-Specific Protein-Protein Interaction Networks Based on “Guilt by Association” Analysis
    Li Wan, Lina Chen, Weiming He, Weiguo Li, Xiaoli Qu, Binhua Liang, Qianping Gao, Chenchen Feng, Jia Xu, Yana Lv et al. · 2013 · PLoS ONE
  69. Dopamine and Renal Function and Blood Pressure Regulation
    Inés Armando, Van Anthony M. Villar, Pedro A. José · 2011 · Comprehensive physiology
  70. Novel transcripts discovered by mining genomic DNA from defined regions of bovine chromosome 6
    Rosemarie Weikard, Tom Goldammer, Annett Eberlein, Christa Kuehn · 2009 · BMC Genomics
  71. A wild derived quantitative trait locus on mouse chromosome 2 prevents obesity
    Md. Bazlur Rahman Mollah, Akira Ishikawa · 2010 · BMC Genetics
  72. A network embedding model for pathogenic genes prediction by multi-path random walking on heterogeneous network
    Bo Xu, Yu Liu, Shuo Yu, Lei Wang, Jie Dong, Hongfei Lin, Zhihao Yang, Jian Wang, Feng Xia · 2019 · BMC Medical Genomics
  73. Genetics in Dental Practice: Social and Ethical Issues Surrounding Genetic Testing
    Elizabeth A. Gettig, Thomas C. Hart · 2003 · Journal of Dental Education
  74. The Role of a Common Adenosine Monophosphate Deaminase (AMPD)-1 Polymorphism in Outcomes of Ischemic and Nonischemic Heart Failure
    Matthew J. Kolek, John F. Carlquist, Surai Thaneemit-Chen, Laura C. Lazzeroni, Bryant M. Whiting, Benjamin Davies Horne, Joseph Boone Muhlestein, Philip William Lavori, Jeffrey L. Anderson · 2005 · Journal of Cardiac Failure
  75. Closely linked non-additive blood pressure quantitative trait loci
    Edward J. Toland, Yasser M. Saad, Shane Yerga‐Woolwine, Steven Ummel, Phyllis Farms, Ramona S. Ramdath, Bryan C. Frank, Norman H. Lee, Bina Joe · 2008 · Mammalian Genome
  76. Ethiopian Cattle Genetic Resource and Unique Characteristics under a Rapidly Changing Production Environment-A Review
    2017 · International Journal of Science and Research (IJSR)
  77. Insight into the genetics of hypertension, a core component of the metabolic syndrome
    Michal Pravenec, Enrico G. Petretto · 2008 · Current Opinion in Clinical Nutrition & Metabolic Care
  78. Genetic analysis of complex cardiovascular traits in the spontaneously hypertensive rat
    Michal Pravenec, Vladimír Křen · 2005 · Experimental Physiology
  79. Sugarcane
    Stevens Michael Brumbley, Sandy J. Snyman, Annathurai Gnanasambandam, Priya Joyce, Scott R. Hermann, Jorge A.G. da Silva, Richard Bruce Mcqualter, Mingli Wang, Brian T. Egan, Andrew H. Paterson et al. · 2008 · Wiley eBooks
  80. Correction: Genetic Networks of Liver Metabolism Revealed by Integration of Metabolic and Transcriptional Profiling
    Christine T. Ferrara, Ping Wang, Elias Chaibub Neto, Robert D. Stevens, James Ralph Bain, Brett R. Wenner, Olga Ilkayeva, Mark P. Keller, Daniel A. Blasiole, Christina M. Kendziorski et al. · 2008 · PLoS Genetics
  81. Epi-MEIF: detecting higher order epistatic interactions for complex traits using mixed effect conditional inference forests
    Saswati Saha, Laurent Perrin, Laurence Röder, Christine Brun, Lionel Spinelli · 2022 · Nucleic Acids Research
  82. Gastrorenal Axis
    Pedro A. José, Robin Allen Felder, Zhiwei Yang, Chunyu Zeng, Gilbert M. Eisner · 2016 · Hypertension
  83. Human genetics of diabetic retinopathy
    Z.-H. Tang, L. Wang, F. Zeng, Kaiyue Zhang · 2014 · Journal of Endocrinological Investigation
  84. Accelerating effect of an MRL gene locus on the severity and onset of arthropathy in DBA/1 mice
    Hisashi Oishi, Tatsuhiko Miyazaki, Shinichi Mizuki, Junji Kamogawa, Ling‐Min Lu, Takahito Tsubaki, Norimasa Arita, Masao Ono, Haruyasu Yamamoto, Masato Nose · 2005 · Arthritis & Rheumatism
  85. Bridging the Gap Between Genomics and Education
    Stephen A. Petrill, Laura Marie Justice · 2007 · Mind Brain and Education
  86. Evaluation of the β2-Adrenergic Receptor Gene as a Candidate Glaucoma Gene in 2 Ancestral Populations
    Ning C. McLaren · 2007 · Archives of Ophthalmology
  87. Yeast selection for wine flavour modulation
    Philippe Marullo, Denis Dubourdieu · 2010 · Elsevier eBooks
  88. QTL mapping for traits associated with stress neuroendocrine reactivity in rats
    Bastien Llamas, Vincent Contesse, Veronique Guyonnet‐Dupérat, Hubert Vaudry, Pierre Mormède, Marie‐Pierre Moisan · 2005 · Mammalian Genome
  89. Gene expression profiling of the left ventricles in a rat model of intrinsic aerobic running capacity
    Soon Jin Lee, Justin A. Ways, John C. Barbato, David A. Essig, Krista M. Pettee, Sarah J. DeRaedt, Siming Yang, David Andrew Weaver, Lauren G. Koch, George Thomas Cicila · 2005 · Physiological Genomics
  90. Genetic networks for the functional study of genomes
    Antonio G. Pisabarro, Gúmer Pérez, José Luis Lavín, Lucı́a Ramı́rez · 2008 · Briefings in Functional Genomics and Proteomics
  91. Disease Gene Prioritization Based on Topological Similarity in Protein-Protein Interaction Networks
    Sinan Erten, Gürkan Bebek, Mehmet Koyutürk · 2011 · Lecture notes in computer science
  92. SFM: A novel sequence-based fusion method for disease genes identification and prioritization
    Abdulaziz Yousef, Nasrollah Moghadam Charkari · 2015 · Journal of Theoretical Biology
  93. DGAT1 polymorphism in Riverine buffalo, Swamp buffalo and crossbred buffalo
    Jun Li, Shenhe Liu, Zipeng Li, Shujun Zhang, Guohua Hua, Angela Salzano, Giuseppe Campanile, Bianca Gasparrini, Aixin Liang, Liguo Yang · 2018 · Journal of Dairy Research
  94. How to approach understanding complex trait genetics – inflammatory bowel disease as a model complex trait
    Isabelle Cleynen, Jonas Halfvarsson · 2019 · United European Gastroenterology Journal
  95. A new PTGDR promoter polymorphism in a population of children with asthma
    Catalina Sanz, María Isidoro‐García, Ignacio J. Davila, Marien Pascual De Pedro, Sonia de Arriba, Juana Padrón, Arturo Ruiz‐SanFrancisco, Felix Lorente · 2008 · Pediatric Allergy and Immunology
  96. Multisite haplotype on cattle chromosome 3 is associated with quantitative trait locus effects on lactation traits
    Miri Weiss Cohen, Ravikiran Donthu, Denis M. Larkin, Charu Gupta Kumar, Sandra L. Rodriguez‐Zas, Kalista E. Andropolis, Rosane Oliveira, Harris A. Lewin · 2011 · Physiological Genomics
  97. A genetic and genomic approach to identify longevity genes in mice
    Gerald de Haan, Robert W. Williams · 2004 · Mechanisms of Ageing and Development
  98. Coregulation of host–response genes in integument: switchover of gene expression correlation pattern and impaired immune responses induced by dipteran parasite infection in the silkworm, Bombyx mori
    Anitha Jayaram, Appukuttan Nair R. Pradeep, Arvind K. Awasthi, Geetha N Murthy, Kangayam M. Ponnuvel, Sirigineedi Sasibhushan, Guruprasad C. Rao · 2013 · Journal of Applied Genetics
  99. Relationships between Some Biodiversity Indicators and Crown Damage of Pinus sylvestris L. in Natural Old Growth Pine Forests
    Paweł Przybylski, Vasyl Mohytych, Paweł Rutkowski, Anna Tereba, Łukasz Tyburski, Kateryna Fyałkowska · 2021 · Sustainability
  100. Gender‐specific polygenic control of ethylnitrosourea‐induced oncogenesis in the rat peripheral nervous system
    Bernd U. Koelsch, Christine Fischer, Markus Neibecker, Nina Schmitt, Ortrud Schmidt, Manfred F. Rajewsky, Andrea Kindler‐Röhrborn · 2005 · International Journal of Cancer